Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50039154
TargetCytochrome P450 3A4(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50259862(cid_10414856 | 13,II8-biapigenin | CHEMBL515252 | ...)
Affinity DataIC50: 80nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50060874(hipericina | hypericine | hypericum red | 1,3,4,6,...)
Affinity DataIC50: 300nMAssay Description:Inhibition of CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50060874(hipericina | hypericine | hypericum red | 1,3,4,6,...)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP formationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50377913(HYPERFORIN)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50060874(hipericina | hypericine | hypericum red | 1,3,4,6,...)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50377913(HYPERFORIN)
Affinity DataKi:  27nMAssay Description:Binding affinity to pregnane receptor in human hepatocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50060874(hipericina | hypericine | hypericum red | 1,3,4,6,...)
Affinity DataKi:  35nMAssay Description:Binding affinity to dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50129952(cid_5281600 | CHEMBL63354 | 8-[5-(5,7-Dihydroxy-4-...)
Affinity DataKi:  37nMAssay Description:Binding affinity to delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  372nMAssay Description:Binding affinity to dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50318294(miquelianin | CHEMBL1098724)
Affinity DataKi:  4.06E+3nMAssay Description:Binding affinity to adrenergic alpha2c receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(4) dopamine receptor(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataKi:  7.85E+3nMAssay Description:Binding affinity to dopamine D4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50217942(3-Rhamnoglucosylquercetin | cid_5280805 | CHEMBL22...)
Affinity DataKi:  9.34E+3nMAssay Description:Binding affinity to adrenergic alpha2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Westfalische Wilhelms-Universitat

Curated by ChEMBL
LigandPNGBDBM50217942(3-Rhamnoglucosylquercetin | cid_5280805 | CHEMBL22...)
Affinity DataKi:  9.64E+3nMAssay Description:Binding affinity to adrenergic alpha2c receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed