Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50039151
LigandPNGBDBM50318137((R)-3-ethyl-5-(3-methylpiperazin-1-yl)-N-(pyrimidi...)
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50318144(3-ethyl-N-(4-fluorophenyl)-5-(piperazin-1-yl)-1-(2...)
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50318136((R)-3-methyl-5-(3-methylpiperazin-1-yl)-N-(pyrimid...)
Affinity DataIC50: 0.140nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50318135(3-ethyl-5-(piperazin-1-yl)-N-(pyrimidin-4-yl)-1-(2...)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50318138(3-ethyl-5-(piperazin-1-yl)-1-(2-propoxyethyl)-N-(p...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50318148(3-ethyl-N5-methyl-N5-(1-methylpiperidin-4-yl)-N7-(...)
Affinity DataIC50: 0.350nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50316650(1-(2-ethoxyethyl)-3-ethyl-5-(piperazin-1-yl)-N-(py...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50318140(3-ethyl-5-(piperazin-1-yl)-N-(pyridin-2-yl)-1-(2-(...)
Affinity DataIC50: 0.650nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50318134(3-methyl-N-(6-methylpyridin-2-yl)-5-(piperazin-1-y...)
Affinity DataIC50: 0.780nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50318139(3-ethyl-1-(2-isopropoxyethyl)-5-(piperazin-1-yl)-N...)
Affinity DataIC50: 0.860nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50318149((S)-3-methyl-5-(3-methylpiperazin-1-yl)-N-(pyrimid...)
Affinity DataIC50: 0.940nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50318141(3-ethyl-N-(6-methylpyridin-2-yl)-5-(piperazin-1-yl...)
Affinity DataIC50: 1nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50316653(1-(2-ethoxyethyl)-3-ethyl-N-(6-methylpyridin-2-yl)...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50318142(3-methyl-N-(4-methylpyridin-2-yl)-5-(piperazin-1-y...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50318152(4-(3-ethyl-7-(pyrimidin-4-ylamino)-1-(2-(2,2,2-tri...)
Affinity DataIC50: 3nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50318146(5-(1,4-diazepan-1-yl)-3-ethyl-N-(pyrimidin-4-yl)-1...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50318143(3-ethyl-N-(4-methylpyridin-2-yl)-5-(piperazin-1-yl...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50318151(3-ethyl-5-morpholino-N-(pyrimidin-4-yl)-1-(2-(2,2,...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50318147(3-ethyl-5-(4-methyl-1,4-diazepan-1-yl)-N-(pyrimidi...)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50318150(N5-(2-aminoethyl)-3-ethyl-N7-(pyrimidin-4-yl)-1-(2...)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50318145(5-(1,4-diazepan-1-yl)-3-methyl-N-(pyrimidin-4-yl)-...)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50318134(3-methyl-N-(6-methylpyridin-2-yl)-5-(piperazin-1-y...)
Affinity DataIC50: 560nMAssay Description:Inhibition of human ERG expressed by patch clam electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50318136((R)-3-methyl-5-(3-methylpiperazin-1-yl)-N-(pyrimid...)
Affinity DataIC50: 900nMAssay Description:Inhibition of human ERG expressed by patch clam electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50318137((R)-3-ethyl-5-(3-methylpiperazin-1-yl)-N-(pyrimidi...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human ERG expressed by patch clam electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50318135(3-ethyl-5-(piperazin-1-yl)-N-(pyrimidin-4-yl)-1-(2...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human ERG expressed by patch clam electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed