Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50031729
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314073(3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-...)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318049(3-(5-bromo-4-(2,4-difluorobenzyloxy)-6-oxopyridazi...)
Affinity DataIC50: 15nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50310984(3-bromo-4-(2,4-difluorobenzyloxy)-1-(4-((dimethyla...)
Affinity DataIC50: 59nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318048(methyl 3-(5-bromo-4-(2,4-difluorobenzyloxy)-6-oxop...)
Affinity DataIC50: 100nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318041(4-bromo-2-(2,6-dichlorophenyl)-5-(2,4-difluorobenz...)
Affinity DataIC50: 160nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318046(4-bromo-2-(3,5-dichloropyridin-4-yl)-5-(2,4-difluo...)
Affinity DataIC50: 250nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318044(4-bromo-2-(2,6-dichlorophenyl)-5-(2,3,4-trifluorob...)
Affinity DataIC50: 470nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318042(4-bromo-2-(2,6-dichlorophenyl)-5-(2,4,6-trifluorob...)
Affinity DataIC50: 540nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318047(4-bromo-5-(2,4-difluorobenzyloxy)-2-(2,6-difluorop...)
Affinity DataIC50: 590nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318050(1-benzyl-4-(benzyloxy)-3-bromopyridin-2(1H)-one | ...)
Affinity DataIC50: 680nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318045(4-bromo-5-(4-chloro-2-fluorobenzyloxy)-2-(2,6-dich...)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318039(4-bromo-2-(2,6-dichlorophenyl)-5-(4-fluorobenzylox...)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318035(5-(benzyloxy)-4-bromo-2-(2,6-dichlorophenyl)pyrida...)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318043(4-bromo-2-(2,6-dichlorophenyl)-5-(3,4-difluorobenz...)
Affinity DataIC50: 2.07E+3nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318034(4-bromo-5-(2,4-difluorobenzyloxy)-2-phenylpyridazi...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318037(4-bromo-2-(2,6-dichlorophenyl)-5-phenethoxypyridaz...)
Affinity DataIC50: 3.14E+3nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318038(4-bromo-2-(2,6-dichlorophenyl)-5-(phenethylamino)p...)
Affinity DataIC50: 3.81E+3nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318036(5-(benzylamino)-4-bromo-2-(2,6-dichlorophenyl)pyri...)
Affinity DataIC50: 5.72E+3nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318040(4-bromo-2-(2,6-dichlorophenyl)-5-(4-fluorobenzylam...)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318033(5-(benzyloxy)-4-bromo-2-phenylpyridazin-3(2H)-one ...)
Affinity DataIC50: 2.44E+4nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318051(2-benzyl-5-(benzyloxy)-4-bromopyridazin-3(2H)-one ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318040(4-bromo-2-(2,6-dichlorophenyl)-5-(4-fluorobenzylam...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318034(4-bromo-5-(2,4-difluorobenzyloxy)-2-phenylpyridazi...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318039(4-bromo-2-(2,6-dichlorophenyl)-5-(4-fluorobenzylox...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318038(4-bromo-2-(2,6-dichlorophenyl)-5-(phenethylamino)p...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318037(4-bromo-2-(2,6-dichlorophenyl)-5-phenethoxypyridaz...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318036(5-(benzylamino)-4-bromo-2-(2,6-dichlorophenyl)pyri...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318035(5-(benzyloxy)-4-bromo-2-(2,6-dichlorophenyl)pyrida...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318043(4-bromo-2-(2,6-dichlorophenyl)-5-(3,4-difluorobenz...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318041(4-bromo-2-(2,6-dichlorophenyl)-5-(2,4-difluorobenz...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318042(4-bromo-2-(2,6-dichlorophenyl)-5-(2,4,6-trifluorob...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318033(5-(benzyloxy)-4-bromo-2-phenylpyridazin-3(2H)-one ...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318051(2-benzyl-5-(benzyloxy)-4-bromopyridazin-3(2H)-one ...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50314073(3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50310984(3-bromo-4-(2,4-difluorobenzyloxy)-1-(4-((dimethyla...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318050(1-benzyl-4-(benzyloxy)-3-bromopyridin-2(1H)-one | ...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318049(3-(5-bromo-4-(2,4-difluorobenzyloxy)-6-oxopyridazi...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318048(methyl 3-(5-bromo-4-(2,4-difluorobenzyloxy)-6-oxop...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318047(4-bromo-5-(2,4-difluorobenzyloxy)-2-(2,6-difluorop...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318046(4-bromo-2-(3,5-dichloropyridin-4-yl)-5-(2,4-difluo...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318045(4-bromo-5-(4-chloro-2-fluorobenzyloxy)-2-(2,6-dich...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50318044(4-bromo-2-(2,6-dichlorophenyl)-5-(2,3,4-trifluorob...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed