Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50039147
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317662(3-[3-(3-Chloro-4-cyanophenyl)-5,5-dimethyl-4-oxo-2...)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at AR in bicalutamide-resistant human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317664(RU-56187 | 2-(trifluoromethyl)-4-(3,4,4-trimethyl-...)
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]mibolerone from human AR expressed in CHO-K1 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317655(3-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Affinity DataIC50: 18nMAssay Description:Antagonist activity at AR in bicalutamide-resistant human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317656(3-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at AR in bicalutamide-resistant human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317660(3-[3-(4-Cyano-3-methylphenyl)-5,5-dimethyl-4-oxo-2...)
Affinity DataIC50: 51nMAssay Description:Antagonist activity at AR in bicalutamide-resistant human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317652(4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Affinity DataIC50: 55nMAssay Description:Antagonist activity at AR in bicalutamide-resistant human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317658(2-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Affinity DataIC50: 79nMAssay Description:Antagonist activity at AR in bicalutamide-resistant human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317657(3-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Affinity DataIC50: 80nMAssay Description:Displacement of [3H]mibolerone from human AR expressed in CHO-K1 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317654(3-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Affinity DataIC50: 89nMAssay Description:Antagonist activity at AR in bicalutamide-resistant human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317659(4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Affinity DataIC50: 110nMAssay Description:Antagonist activity at AR in bicalutamide-resistant human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317655(3-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Affinity DataIC50: 160nMAssay Description:Antagonist activity at AR in human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317656(3-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Affinity DataIC50: 170nMAssay Description:Displacement of [3H]mibolerone from human AR expressed in CHO-K1 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317656(3-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Affinity DataIC50: 190nMAssay Description:Antagonist activity at AR in human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317653(3-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at AR in bicalutamide-resistant human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM18525(N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...)
Affinity DataIC50: 200nMAssay Description:Displacement of [3H]mibolerone from human AR expressed in CHO-K1 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317663(3-[3-(4-Cyano-2-methyl-3-trifluoromethylphenyl)-5,...)
Affinity DataIC50: 260nMAssay Description:Displacement of [3H]mibolerone from human AR expressed in CHO-K1 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317660(3-[3-(4-Cyano-3-methylphenyl)-5,5-dimethyl-4-oxo-2...)
Affinity DataIC50: 300nMAssay Description:Antagonist activity at AR in human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317655(3-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Affinity DataIC50: 400nMAssay Description:Displacement of [3H]mibolerone from human AR expressed in CHO-K1 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317652(4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Affinity DataIC50: 400nMAssay Description:Antagonist activity at AR in human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317651(4-[3-(4-cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Affinity DataIC50: 400nMAssay Description:Antagonist activity at AR in bicalutamide-resistant human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317662(3-[3-(3-Chloro-4-cyanophenyl)-5,5-dimethyl-4-oxo-2...)
Affinity DataIC50: 410nMAssay Description:Antagonist activity at AR in human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317662(3-[3-(3-Chloro-4-cyanophenyl)-5,5-dimethyl-4-oxo-2...)
Affinity DataIC50: 440nMAssay Description:Displacement of [3H]mibolerone from human AR expressed in CHO-K1 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317652(4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Affinity DataIC50: 480nMAssay Description:Displacement of [3H]mibolerone from human AR expressed in CHO-K1 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM18525(N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...)
Affinity DataIC50: 550nMAssay Description:Antagonist activity at AR in bicalutamide-resistant human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317658(2-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Affinity DataIC50: 750nMAssay Description:Antagonist activity at AR in human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317658(2-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Affinity DataIC50: 770nMAssay Description:Displacement of [3H]mibolerone from human AR expressed in CHO-K1 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317654(3-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Affinity DataIC50: 780nMAssay Description:Antagonist activity at AR in human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317653(3-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Affinity DataIC50: 800nMAssay Description:Displacement of [3H]mibolerone from human AR expressed in CHO-K1 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317660(3-[3-(4-Cyano-3-methylphenyl)-5,5-dimethyl-4-oxo-2...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]mibolerone from human AR expressed in CHO-K1 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317659(4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]mibolerone from human AR expressed in CHO-K1 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317654(3-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]mibolerone from human AR expressed in CHO-K1 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317665(4-{4,4-Dimethyl-5-oxo-3-[3-(1H-tetrazol-5-yl)propy...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]mibolerone from human AR expressed in CHO-K1 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317666(3-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]mibolerone from human AR expressed in CHO-K1 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317663(3-[3-(4-Cyano-2-methyl-3-trifluoromethylphenyl)-5,...)
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at AR in human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317659(4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Affinity DataIC50: 1.40E+3nMAssay Description:Antagonist activity at AR in human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317653(3-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Affinity DataIC50: 1.60E+3nMAssay Description:Antagonist activity at AR in human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317661(3-[3-(4-Cyano-3-methoxyphenyl)-5,5-dimethyl-4-oxo-...)
Affinity DataIC50: 1.90E+3nMAssay Description:Displacement of [3H]mibolerone from human AR expressed in CHO-K1 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317661(3-[3-(4-Cyano-3-methoxyphenyl)-5,5-dimethyl-4-oxo-...)
Affinity DataIC50: 1.90E+3nMAssay Description:Antagonist activity at AR in human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317651(4-[3-(4-cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist activity at AR in human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317657(3-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Affinity DataIC50: 3.70E+3nMAssay Description:Antagonist activity at AR in human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317651(4-[3-(4-cyano-3-trifluoromethylphenyl)-5,5-dimethy...)
Affinity DataIC50: 3.90E+3nMAssay Description:Displacement of [3H]mibolerone from human AR expressed in CHO-K1 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317667(3-[3-(4-Cyanophenyl)-5,5-dimethyl-4-oxo-2-thioxoim...)
Affinity DataIC50: 5.00E+3nMAssay Description:Displacement of [3H]mibolerone from human AR expressed in CHO-K1 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50317668(3-[3-(4-Cyano-2-methyl-5-trifluoromethylphenyl)-5,...)
Affinity DataIC50: 5.00E+3nMAssay Description:Displacement of [3H]mibolerone from human AR expressed in CHO-K1 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed