Compile Data Set for Download or QSAR
Report error Found 69 Enz. Inhib. hit(s) with all data for entry = 50031690
TargetVascular endothelial growth factor receptor 2(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50306503(4,4,4-trifluoro-3-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50: 10nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50247962(N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno...)
Affinity DataIC50: 10nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50247962(N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno...)
Affinity DataIC50: 20nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317333((S)-N-(3-fluoro-4-(2-(4-((N-(1-methoxypropan-2-yl)...)
Affinity DataIC50: 30nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317338(6-(7-(2-fluoro-4-(1-phenyl-5-(trifluoromethyl)-1H-...)
Affinity DataIC50: 30nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317335(N-(4-(2-(4-(dimethylcarbamoyl)phenyl)thieno[3,2-b]...)
Affinity DataIC50: 30nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317336(N-(4-(2-(4-((2-(dimethylamino)ethyl)(methyl)carbam...)
Affinity DataIC50: 30nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317339(6-(7-(2-fluoro-4-(1-phenyl-5-(trifluoromethyl)-1H-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317338(6-(7-(2-fluoro-4-(1-phenyl-5-(trifluoromethyl)-1H-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317337((S)-N-(4-(2-(4-(3-(dimethylamino)pyrrolidine-1-car...)
Affinity DataIC50: 40nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317323(N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno...)
Affinity DataIC50: 50nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317335(N-(4-(2-(4-(dimethylcarbamoyl)phenyl)thieno[3,2-b]...)
Affinity DataIC50: 50nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317340(N-(4-(2-(1-acetyl-1,2,3,6-tetrahydropyridin-4-yl)t...)
Affinity DataIC50: 50nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317339(6-(7-(2-fluoro-4-(1-phenyl-5-(trifluoromethyl)-1H-...)
Affinity DataIC50: 60nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317334(N-(3-fluoro-4-(2-(4-((2-(methylsulfonyl)ethylamino...)
Affinity DataIC50: 60nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317330(N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno...)
Affinity DataIC50: 60nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317333((S)-N-(3-fluoro-4-(2-(4-((N-(1-methoxypropan-2-yl)...)
Affinity DataIC50: 60nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317332(N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-2-yl)thieno...)
Affinity DataIC50: 60nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50247962(N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno...)
Affinity DataIC50: 70nMAssay Description:Inhibition of c-Met phosphorylation in human MKN45 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317331(1-tert-butyl-N-(3-fluoro-4-(2-(1-methyl-1H-imidazo...)
Affinity DataIC50: 70nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317327(N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno...)
Affinity DataIC50: 70nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317326(N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno...)
Affinity DataIC50: 70nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317334(N-(3-fluoro-4-(2-(4-((2-(methylsulfonyl)ethylamino...)
Affinity DataIC50: 80nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50247962(N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno...)
Affinity DataIC50: 80nMAssay Description:Inhibition of c-Met-mediated cell migration of human A549 cells by would healingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317328(N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno...)
Affinity DataIC50: 80nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50247962(N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno...)
Affinity DataIC50: 80nMAssay Description:Inhibition of c-Met-mediated scattering in HGF-stimulated human DU145 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317324(N-(4-(6,7-dimethoxyquinolin-4-yloxy)-3-fluoropheny...)
Affinity DataIC50: 80nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317336(N-(4-(2-(4-((2-(dimethylamino)ethyl)(methyl)carbam...)
Affinity DataIC50: 90nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317340(N-(4-(2-(1-acetyl-1,2,3,6-tetrahydropyridin-4-yl)t...)
Affinity DataIC50: 90nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317337((S)-N-(4-(2-(4-(3-(dimethylamino)pyrrolidine-1-car...)
Affinity DataIC50: 100nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50306503(4,4,4-trifluoro-3-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50: 120nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317326(N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno...)
Affinity DataIC50: 150nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317332(N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-2-yl)thieno...)
Affinity DataIC50: 150nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317323(N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno...)
Affinity DataIC50: 150nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50247962(N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno...)
Affinity DataIC50: 170nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317329(5-amino-N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-y...)
Affinity DataIC50: 180nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317324(N-(4-(6,7-dimethoxyquinolin-4-yloxy)-3-fluoropheny...)
Affinity DataIC50: 200nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317331(1-tert-butyl-N-(3-fluoro-4-(2-(1-methyl-1H-imidazo...)
Affinity DataIC50: 200nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50306507(4,4,4-trifluoro-N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50: 210nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317327(N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno...)
Affinity DataIC50: 210nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317323(N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno...)
Affinity DataIC50: 400nMAssay Description:Inhibition of c-Met-mediated cell migration of human A549 cells by would healingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50306507(4,4,4-trifluoro-N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50: 410nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317323(N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno...)
Affinity DataIC50: 500nMAssay Description:Inhibition of c-Met phosphorylation in human MKN45 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317328(N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno...)
Affinity DataIC50: 590nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50306507(4,4,4-trifluoro-N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50: 700nMAssay Description:Inhibition of c-MetMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317336(N-(4-(2-(4-((2-(dimethylamino)ethyl)(methyl)carbam...)
Affinity DataIC50: 700nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317330(N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno...)
Affinity DataIC50: 700nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317329(5-amino-N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-y...)
Affinity DataIC50: 800nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317329(5-amino-N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-y...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50317330(N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of TPR-tagged RON catalytic domain expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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