Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50031601
TargetGlycine receptor subunit alpha-1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50316015(8-hydroxyircinialactam B | CHEMBL1093847)
Affinity DataEC50:  500nMAssay Description:Agonist activity at human recombinant alpha 1 GlyR expressed in HEK293 cells assessed as potentiation of glycine current by whole cell patch clamp as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50316020((12E,20Z,18S)-8-hydroxyvariabilin | 5-((2S)-13-(fu...)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at human recombinant alpha 1 GlyR expressed in HEK293 cells assessed as potentiation of glycine current by whole cell patch clamp as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-3(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50316020((12E,20Z,18S)-8-hydroxyvariabilin | 5-((2S)-13-(fu...)
Affinity DataIC50: 7.00E+3nMAssay Description:Antagonist activity at human recombinant alpha 3 GlyR expressed in HEK293 cells assessed as inhibition of glycine current influx by whole cell patch ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-3(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50316016(ircinialactam C | CHEMBL1093848)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human recombinant alpha 3 GlyR expressed in HEK293 cells assessed as inhibition of glycine current influx by whole cell patch ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-3(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50316017(ent-ircinialactam C | CHEMBL1092618)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human recombinant alpha 3 GlyR expressed in HEK293 cells assessed as inhibition of glycine current influx by whole cell patch ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-3(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50316018(ircinialactam D | CHEMBL1092619)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human recombinant alpha 3 GlyR expressed in HEK293 cells assessed as inhibition of glycine current influx by whole cell patch ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-3(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50316019(ircinialactam A | CHEMBL1093582)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human recombinant alpha 3 GlyR expressed in HEK293 cells assessed as inhibition of glycine current influx by whole cell patch ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed