Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50031592
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50309525(2-(5-(4-(4-fluorobenzyl)piperidine-1-carbonyl)-6-m...)
Affinity DataIC50: 10nMAssay Description:Inhibition of p38alpha assessed as inhibition of gamma-32p-ATP incorporation into biotin peptide substrate after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM15240(4-[1-methyl-2-(piperidin-4-yl)-4-[3-(trifluorometh...)
Affinity DataIC50: 110nMAssay Description:Inhibition of p38alpha assessed as inhibition of gamma-32p-ATP incorporation into biotin peptide substrate after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315875((S)-N-ethyl-N-(2-(1-phenylethylamino)pyridin-4-yl)...)
Affinity DataIC50: 313nMAssay Description:Inhibition of p38alpha assessed as inhibition of gamma-32p-ATP incorporation into biotin peptide substrate after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315867((S)-N-(4-fluorobenzyl)-N-(2-(1-phenylethylamino)py...)
Affinity DataIC50: 345nMAssay Description:Inhibition of p38alpha assessed as inhibition of gamma-32p-ATP incorporation into biotin peptide substrate after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315874((S)-N-(4-fluorobenzyl)-N-(2-(1-phenylethylamino)py...)
Affinity DataIC50: 408nMAssay Description:Inhibition of p38alpha assessed as inhibition of gamma-32p-ATP incorporation into biotin peptide substrate after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315873((S)-N-(4-fluorobenzyl)-N-(2-(1-phenylethylamino)py...)
Affinity DataIC50: 589nMAssay Description:Inhibition of p38alpha assessed as inhibition of gamma-32p-ATP incorporation into biotin peptide substrate after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315872(N-(4-fluorobenzyl)-N-(2-(isopropylamino)pyridin-4-...)
Affinity DataIC50: 671nMAssay Description:Inhibition of p38alpha assessed as inhibition of gamma-32p-ATP incorporation into biotin peptide substrate after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315871(N-(2-(cyclohexylamino)pyridin-4-yl)-N-(4-fluoroben...)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of p38alpha assessed as inhibition of gamma-32p-ATP incorporation into biotin peptide substrate after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315877(N-(4-fluorobenzyl)-N-(2-((S)-1-phenylethylamino)py...)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of p38alpha assessed as inhibition of gamma-32p-ATP incorporation into biotin peptide substrate after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315869(N-(2-(benzylamino)pyridin-4-yl)-N-(4-fluorobenzyl)...)
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of p38alpha assessed as inhibition of gamma-32p-ATP incorporation into biotin peptide substrate after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315866(N-(4-fluorobenzyl)-N-(pyridin-4-yl)-2-naphthamide ...)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of p38alpha assessed as inhibition of gamma-32p-ATP incorporation into biotin peptide substrate after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315870(N-(2-aminopyridin-4-yl)-N-(4-fluorobenzyl)-2-napht...)
Affinity DataIC50: 5.08E+3nMAssay Description:Inhibition of p38alpha assessed as inhibition of gamma-32p-ATP incorporation into biotin peptide substrate after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315876((S)-N-(4-fluorobenzyl)-N-(2-(1-phenylethylamino)py...)
Affinity DataIC50: 7.54E+3nMAssay Description:Inhibition of p38alpha assessed as inhibition of gamma-32p-ATP incorporation into biotin peptide substrate after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50315868((R)-N-(4-fluorobenzyl)-N-(2-(1-phenylethylamino)py...)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of p38alpha assessed as inhibition of gamma-32p-ATP incorporation into biotin peptide substrate after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed