Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50031557
TargetProstaglandin G/H synthase 1(Sheep)
University of Graz

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of ram seminal vesicle COX1 assessed as PGE2 level by EIAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
University of Graz

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | NS398 | NS-398 | N-(2-Cyclohexyloxy-4...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of sheep placental cotyledens COX2 assessed as PGE2 level by EIAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Graz

Curated by ChEMBL
LigandPNGBDBM50315285(aR-6,7-dihydro-6-(10-hydroxyethyl)-3,9-dimethoxy-6...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of 5-LOX-mediated LTB4 production in stimulated human neutrophile granulocytes after 10 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Graz

Curated by ChEMBL
LigandPNGBDBM50315286(aR-6-(10-iodoethyl)-1,2,3,9,10,11-hexamethoxy-6-me...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of 5-LOX-mediated LTB4 production in stimulated human neutrophile granulocytes after 10 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Graz

Curated by ChEMBL
LigandPNGBDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of 5-LOX-mediated LTB4 production in stimulated human neutrophile granulocytes after 10 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
University of Graz

Curated by ChEMBL
LigandPNGBDBM50315284(aR-6,7-Dihydro-6-(10-hydroxyethyl)-6-methyl-5H-dib...)
Affinity DataIC50: 3.21E+4nMAssay Description:Inhibition of sheep placental cotyledens COX2 assessed as PGE2 level by EIAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed