Compile Data Set for Download or QSAR
Report error Found 59 Enz. Inhib. hit(s) with all data for entry = 50031532
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314845(3'-(4-Chlorophenyl-1,2,3-triazol-1-yl)-3'-deoxy-be...)
Affinity DataKi:  12nMAssay Description:Competitive inhibition of human recombinant mitochondrial thymidine kinase 2 using ATP as substrate by Lineweaver-Burke plottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314845(3'-(4-Chlorophenyl-1,2,3-triazol-1-yl)-3'-deoxy-be...)
Affinity DataIC50: 36nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314840(3'-Deoxy-3'-(4-(3,4-dichlorophenyl)-1,2,3-triazol-...)
Affinity DataIC50: 42nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314839(3'-(4-Chlorophenyl-1,2,3-triazol-1-yl)-3'-deoxy-be...)
Affinity DataIC50: 46nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314848(3'-hexanoylamino-3'-deoxythymidine | CHEMBL1089836)
Affinity DataKi:  150nMAssay Description:Uncompetitive inhibition of human recombinant mitochondrial thymidine kinase 2 using thymidine as substrate by Lineweaver-Burke plottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314850(1-(4-chloro-3-(trifluoromethyl)phenyl)-3-((2S,3S,5...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314838(3'-(4-Cyclopentylmethyl-1,2,3-triazol-1-yl)-3'-deo...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314835(3'-(4-Butyl-1,2,3-triazol-1-yl)-3'-deoxy-beta-D-th...)
Affinity DataIC50: 230nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314844(3'-Deoxy-3'-(4-phenyl-1,2,3-triazol-1-yl)-beta-(E)...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314837(3'-(4-Benzyl-1,2,3-triazol-1-yl)-3'-deoxythymidine...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314836(3'-Deoxy-3'-(4-phenyl-1,2,3-triazol-1-yl)-beta-D-t...)
Affinity DataIC50: 320nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314849(N-methyl-4-((8-(5-methyl-2,4-dioxo-3,4-dihydropyri...)
Affinity DataIC50: 400nMAssay Description:Uncompetitive inhibition of human recombinant mitochondrial thymidine kinase 2 using thymidine as substrate by Lineweaver-Burke plottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314845(3'-(4-Chlorophenyl-1,2,3-triazol-1-yl)-3'-deoxy-be...)
Affinity DataKi:  410nMAssay Description:Uncompetitive inhibition of human recombinant mitochondrial thymidine kinase 2 using thymidine as substrate by Lineweaver-Burke plottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetDeoxynucleoside kinase(Fruit fly)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314845(3'-(4-Chlorophenyl-1,2,3-triazol-1-yl)-3'-deoxy-be...)
Affinity DataIC50: 460nMAssay Description:Inhibition of Drosophila melanogaster multifunctional deoxynucleoside kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetDeoxynucleoside kinase(Fruit fly)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314840(3'-Deoxy-3'-(4-(3,4-dichlorophenyl)-1,2,3-triazol-...)
Affinity DataIC50: 990nMAssay Description:Inhibition of Drosophila melanogaster multifunctional deoxynucleoside kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314842(3'-Deoxy-3'-(5-phenyl-1,2,3-triazol-1-yl)-beta-D-t...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314841(3'-Deoxy-3'-(4-pyridin-2-yl-1,2,3-triazol-1-yl)-be...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50118490(1-[(Z)-4-(triphenylmethoxy)-2-butenyl]thymine | 5-...)
Affinity DataIC50: 1.50E+3nMAssay Description:Uncompetitive inhibition of human recombinant mitochondrial thymidine kinase 2 using thymidine as substrate by Lineweaver-Burke plottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetDeoxynucleoside kinase(Fruit fly)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314839(3'-(4-Chlorophenyl-1,2,3-triazol-1-yl)-3'-deoxy-be...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of Drosophila melanogaster multifunctional deoxynucleoside kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetDeoxynucleoside kinase(Fruit fly)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314836(3'-Deoxy-3'-(4-phenyl-1,2,3-triazol-1-yl)-beta-D-t...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of Drosophila melanogaster multifunctional deoxynucleoside kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetDeoxynucleoside kinase(Fruit fly)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314844(3'-Deoxy-3'-(4-phenyl-1,2,3-triazol-1-yl)-beta-(E)...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of Drosophila melanogaster multifunctional deoxynucleoside kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetDeoxynucleoside kinase(Fruit fly)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314838(3'-(4-Cyclopentylmethyl-1,2,3-triazol-1-yl)-3'-deo...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Drosophila melanogaster multifunctional deoxynucleoside kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetDeoxynucleoside kinase(Fruit fly)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314841(3'-Deoxy-3'-(4-pyridin-2-yl-1,2,3-triazol-1-yl)-be...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of Drosophila melanogaster multifunctional deoxynucleoside kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetDeoxynucleoside kinase(Fruit fly)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314837(3'-(4-Benzyl-1,2,3-triazol-1-yl)-3'-deoxythymidine...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of Drosophila melanogaster multifunctional deoxynucleoside kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314843(3'-(5-(4-Chlorophenyl)-1,2,3-triazol-1-yl)-3'-deox...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetDeoxynucleoside kinase(Fruit fly)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314835(3'-(4-Butyl-1,2,3-triazol-1-yl)-3'-deoxy-beta-D-th...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of Drosophila melanogaster multifunctional deoxynucleoside kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314845(3'-(4-Chlorophenyl-1,2,3-triazol-1-yl)-3'-deoxy-be...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of HSV1 thymidine kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314847(3'-(1,2,3-Triazol-1-yl)-3'-deoxy-beta-D-thymidine ...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human recombinant mitochondrial thymidine kinase 2 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50206488((2R,3S,4R,5R)-2-(5-(2-bromovinyl)-2,4-dioxo-3,4-di...)
Affinity DataIC50: 6.30E+3nMAssay Description:Uncompetitive inhibition of human recombinant mitochondrial thymidine kinase 2 using thymidine as substrate by Lineweaver-Burke plottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50206491(CHEMBL70046 | 1-beta-D-arabinofuranosyl-5-(2-bromo...)
Affinity DataKi:  1.04E+4nMAssay Description:Uncompetitive inhibition of human recombinant mitochondrial thymidine kinase 2 using thymidine as substrate by Lineweaver-Burke plottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetDeoxynucleoside kinase(Fruit fly)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314842(3'-Deoxy-3'-(5-phenyl-1,2,3-triazol-1-yl)-beta-D-t...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of Drosophila melanogaster multifunctional deoxynucleoside kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314839(3'-(4-Chlorophenyl-1,2,3-triazol-1-yl)-3'-deoxy-be...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of HSV1 thymidine kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314836(3'-Deoxy-3'-(4-phenyl-1,2,3-triazol-1-yl)-beta-D-t...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of HSV1 thymidine kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314840(3'-Deoxy-3'-(4-(3,4-dichlorophenyl)-1,2,3-triazol-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of HSV1 thymidine kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetDeoxynucleoside kinase(Fruit fly)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314843(3'-(5-(4-Chlorophenyl)-1,2,3-triazol-1-yl)-3'-deox...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Drosophila melanogaster multifunctional deoxynucleoside kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314844(3'-Deoxy-3'-(4-phenyl-1,2,3-triazol-1-yl)-beta-(E)...)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of HSV1 thymidine kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetDeoxynucleoside kinase(Fruit fly)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314847(3'-(1,2,3-Triazol-1-yl)-3'-deoxy-beta-D-thymidine ...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of Drosophila melanogaster multifunctional deoxynucleoside kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314841(3'-Deoxy-3'-(4-pyridin-2-yl-1,2,3-triazol-1-yl)-be...)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of HSV1 thymidine kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314838(3'-(4-Cyclopentylmethyl-1,2,3-triazol-1-yl)-3'-deo...)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of HSV1 thymidine kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase, cytosolic(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314836(3'-Deoxy-3'-(4-phenyl-1,2,3-triazol-1-yl)-beta-D-t...)
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of human recombinant cytosolic thymidine kinase 1 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase, cytosolic(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314839(3'-(4-Chlorophenyl-1,2,3-triazol-1-yl)-3'-deoxy-be...)
Affinity DataIC50: 7.10E+4nMAssay Description:Inhibition of human recombinant cytosolic thymidine kinase 1 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase, cytosolic(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314840(3'-Deoxy-3'-(4-(3,4-dichlorophenyl)-1,2,3-triazol-...)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of human recombinant cytosolic thymidine kinase 1 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314835(3'-(4-Butyl-1,2,3-triazol-1-yl)-3'-deoxy-beta-D-th...)
Affinity DataIC50: 9.50E+4nMAssay Description:Inhibition of HSV1 thymidine kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase, cytosolic(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314843(3'-(5-(4-Chlorophenyl)-1,2,3-triazol-1-yl)-3'-deox...)
Affinity DataIC50: 1.09E+5nMAssay Description:Inhibition of human recombinant cytosolic thymidine kinase 1 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314837(3'-(4-Benzyl-1,2,3-triazol-1-yl)-3'-deoxythymidine...)
Affinity DataIC50: 1.58E+5nMAssay Description:Inhibition of HSV1 thymidine kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase, cytosolic(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314838(3'-(4-Cyclopentylmethyl-1,2,3-triazol-1-yl)-3'-deo...)
Affinity DataIC50: 1.77E+5nMAssay Description:Inhibition of human recombinant cytosolic thymidine kinase 1 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314847(3'-(1,2,3-Triazol-1-yl)-3'-deoxy-beta-D-thymidine ...)
Affinity DataIC50: 2.12E+5nMAssay Description:Inhibition of HSV1 thymidine kinase assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase, cytosolic(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314850(1-(4-chloro-3-(trifluoromethyl)phenyl)-3-((2S,3S,5...)
Affinity DataIC50: 3.16E+5nMAssay Description:Inhibition of human recombinant cytosolic thymidine kinase 1 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase, cytosolic(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314841(3'-Deoxy-3'-(4-pyridin-2-yl-1,2,3-triazol-1-yl)-be...)
Affinity DataIC50: 3.16E+5nMAssay Description:Inhibition of human recombinant cytosolic thymidine kinase 1 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetThymidine kinase, cytosolic(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50314837(3'-(4-Benzyl-1,2,3-triazol-1-yl)-3'-deoxythymidine...)
Affinity DataIC50: 3.18E+5nMAssay Description:Inhibition of human recombinant cytosolic thymidine kinase 1 assessed as inhibition of [methyl-3H]dThd phosphorylation after 30 mins by scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
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