Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50031526
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50314759(US8629154, 1.1(1) | CHEMBL1091206 | 2-(methylthio)...)
Affinity DataIC50: 6nMAssay Description:Antagonist activity at human 5HT6 receptor in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation pretreated for 15 mins befor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50314760(CHEMBL1091207 | US8629154, 1.2(1) | 2-(methylthio)...)
Affinity DataIC50: 7.5nMAssay Description:Antagonist activity at human 5HT6 receptor in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation pretreated for 15 mins befor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50314763(US8629154, 2(2) | CHEMBL1092241 | 9-methyl-2-(meth...)
Affinity DataIC50: 7.80nMAssay Description:Antagonist activity at human 5HT6 receptor in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation pretreated for 15 mins befor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50314762(US8629154, 1.2(3) | 5-methyl-2-(methylthio)-3-(phe...)
Affinity DataIC50: 16.8nMAssay Description:Antagonist activity at human 5HT6 receptor in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation pretreated for 15 mins befor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50314761(US8629154, 2(1) | CHEMBL1091208 | 2-Methylsulfanyl...)
Affinity DataIC50: 98.5nMAssay Description:Antagonist activity at human 5HT6 receptor in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation pretreated for 15 mins befor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50314759(US8629154, 1.1(1) | CHEMBL1091206 | 2-(methylthio)...)
Affinity DataIC50: 118nMAssay Description:Antagonist activity at human 5HT2B receptor in HEK293 cells assessed as inhibition of alpha-ME-5-HT-induced cAMP accumulation pretreated for 15 secs ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50314763(US8629154, 2(2) | CHEMBL1092241 | 9-methyl-2-(meth...)
Affinity DataIC50: 127nMAssay Description:Antagonist activity at human 5HT2B receptor in HEK293 cells assessed as inhibition of alpha-ME-5-HT-induced cAMP accumulation pretreated for 15 secs ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50314762(US8629154, 1.2(3) | 5-methyl-2-(methylthio)-3-(phe...)
Affinity DataIC50: 161nMAssay Description:Antagonist activity at human 5HT2B receptor in HEK293 cells assessed as inhibition of alpha-ME-5-HT-induced cAMP accumulation pretreated for 15 secs ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50314760(CHEMBL1091207 | US8629154, 1.2(1) | 2-(methylthio)...)
Affinity DataIC50: 411nMAssay Description:Antagonist activity at human 5HT2B receptor in HEK293 cells assessed as inhibition of alpha-ME-5-HT-induced cAMP accumulation pretreated for 15 secs ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50314762(US8629154, 1.2(3) | 5-methyl-2-(methylthio)-3-(phe...)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human recombinant ERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50314762(US8629154, 1.2(3) | 5-methyl-2-(methylthio)-3-(phe...)
Affinity DataKi:  0.440nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor in humanHeLa cells after 120 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50314759(US8629154, 1.1(1) | CHEMBL1091206 | 2-(methylthio)...)
Affinity DataKi:  0.458nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor in humanHeLa cells after 120 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50314760(CHEMBL1091207 | US8629154, 1.2(1) | 2-(methylthio)...)
Affinity DataKi:  0.549nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor in humanHeLa cells after 120 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50314763(US8629154, 2(2) | CHEMBL1092241 | 9-methyl-2-(meth...)
Affinity DataKi:  0.680nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor in humanHeLa cells after 120 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50314761(US8629154, 2(1) | CHEMBL1091208 | 2-Methylsulfanyl...)
Affinity DataKi:  7.97nMAssay Description:Displacement of [3H]LSD from 5HT6 receptor in humanHeLa cells after 120 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed