Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50031510
TargetGlycogen synthase kinase-3 beta(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313664(N-(6-chloro-5-(furan-3-yl)-1H-indazol-3-yl)butyram...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant GSK3-beta by kinetic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313678(N-(5-bromo-6-(4-hydroxyphenyl)-1H-indazol-3-yl)but...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant GSK3-beta by kinetic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313661(N-(6-chloro-5-phenyl-1H-indazol-3-yl)butanamide | ...)
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant GSK3-beta by kinetic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313663(N-(6-chloro-5-(4-hydroxyphenyl)-1H-indazol-3-yl)bu...)
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant GSK3-beta by kinetic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313668(N-(6-chloro-5-(4-fluorophenyl)-1H-indazol-3-yl)but...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant GSK3-beta by kinetic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50314525(1-(6-chloro-5-phenyl-1H-indazol-3-yl)-3-phenylurea...)
Affinity DataIC50: 270nMAssay Description:Inhibition of GSK3-beta assessed as tau phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313656(N-(6-phenyl-1H-indazol-3-yl)butyramide | CHEMBL108...)
Affinity DataIC50: 390nMAssay Description:Inhibition of human recombinant GSK3-beta by kinetic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313700(N-(5-bromo-6-chloro-1H-indazol-3-yl)butyramide | C...)
Affinity DataIC50: 550nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313668(N-(6-chloro-5-(4-fluorophenyl)-1H-indazol-3-yl)but...)
Affinity DataIC50: 830nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313662(N-(5-(4-aminophenyl)-6-chloro-1H-indazol-3-yl)buty...)
Affinity DataIC50: 980nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313686(N-(6-(pyridin-3-yl)-1H-indazol-3-yl)butyramide | C...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313666(N-(6-chloro-5-p-tolyl-1H-indazol-3-yl)butyramide |...)
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313653(N-(6-(thiophen-3-yl)-1H-indazol-3-yl)butyramide | ...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313659(N-(6-(3,5-difluorophenyl)-1H-indazol-3-yl)butyrami...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human recombinant GSK3-beta by kinetic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313667(N-(6-chloro-5-(4-nitrophenyl)-1H-indazol-3-yl)buty...)
Affinity DataIC50: 4.46E+3nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313686(N-(6-(pyridin-3-yl)-1H-indazol-3-yl)butyramide | C...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human recombinant GSK3-beta by kinetic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313661(N-(6-chloro-5-phenyl-1H-indazol-3-yl)butanamide | ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50314525(1-(6-chloro-5-phenyl-1H-indazol-3-yl)-3-phenylurea...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C19(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313661(N-(6-chloro-5-phenyl-1H-indazol-3-yl)butanamide | ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP2C19More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C19(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313678(N-(5-bromo-6-(4-hydroxyphenyl)-1H-indazol-3-yl)but...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP2C19More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313661(N-(6-chloro-5-phenyl-1H-indazol-3-yl)butanamide | ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313678(N-(5-bromo-6-(4-hydroxyphenyl)-1H-indazol-3-yl)but...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313678(N-(5-bromo-6-(4-hydroxyphenyl)-1H-indazol-3-yl)but...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313656(N-(6-phenyl-1H-indazol-3-yl)butyramide | CHEMBL108...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313678(N-(5-bromo-6-(4-hydroxyphenyl)-1H-indazol-3-yl)but...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313661(N-(6-chloro-5-phenyl-1H-indazol-3-yl)butanamide | ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313678(N-(5-bromo-6-(4-hydroxyphenyl)-1H-indazol-3-yl)but...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313669(N-(5-(4-(benzyloxy)phenyl)-6-chloro-1H-indazol-3-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313659(N-(6-(3,5-difluorophenyl)-1H-indazol-3-yl)butyrami...)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313698(N-[6-(4-hydroxyphenyl)-1H-indazol-3-yl]butanamide ...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human recombinant GSK3-beta by kinetic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313701(4-(6-chloro-1H-indazol-3-ylamino)-4-oxobutanoic ac...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313698(N-[6-(4-hydroxyphenyl)-1H-indazol-3-yl]butanamide ...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed