Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50031138
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50307941(N-(4-(3-Bromoanilino)quinazolin-6-yl)-2-cyanoaceta...)
Affinity DataIC50: 0.170nMAssay Description:Inhibition of human recombinant EGFR expressed in insect cells by time-resolved fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50307940(N-(4-(3-Bromoanilino)quinazolin-6-yl)-2-(3-oxoisot...)
Affinity DataIC50: 0.360nMAssay Description:Inhibition of human recombinant EGFR expressed in insect cells by time-resolved fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50307939(N-[2-[(4-(3-Bromoanilino)quinazolin-6-yl)amino]-2-...)
Affinity DataIC50: 0.370nMAssay Description:Inhibition of human recombinant EGFR expressed in insect cells by time-resolved fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50307936(N-(4-(3-Bromoanilino)quinazolin-6-yl)-2-(3-oxobenz...)
Affinity DataIC50: 0.850nMAssay Description:Inhibition of human recombinant EGFR expressed in insect cells by time-resolved fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50307935((2R,3S)-N-(4-(3-Bromoanilino)quinazolin-6-yl)-3-(p...)
Affinity DataIC50: 1.24nMAssay Description:Inhibition of human recombinant EGFR expressed in insect cells by time-resolved fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM4567(CHEMBL285063 | N-{4-[(3-bromophenyl)amino]quinazol...)
Affinity DataIC50: 1.69nMAssay Description:Inhibition of human recombinant EGFR expressed in insect cells by time-resolved fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50307935((2R,3S)-N-(4-(3-Bromoanilino)quinazolin-6-yl)-3-(p...)
Affinity DataIC50: 7nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cells after 1 hr by Western blotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50307934(N-(4-(3-Bromoanilino)quinazolin-6-yl)-2-(4-fluorop...)
Affinity DataIC50: 8.43nMAssay Description:Inhibition of human recombinant EGFR expressed in insect cells by time-resolved fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50307933(N-(4-(3-Bromoanilino)quinazolin-6-yl)-2-phenoxyace...)
Affinity DataIC50: 9.25nMAssay Description:Inhibition of human recombinant EGFR expressed in insect cells by time-resolved fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM4567(CHEMBL285063 | N-{4-[(3-bromophenyl)amino]quinazol...)
Affinity DataIC50: 12nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cells after 1 hr by Western blotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50307932(N-(4-(3-Bromoanilino)quinazolin-6-yl)-2-(perfluoro...)
Affinity DataIC50: 23.6nMAssay Description:Inhibition of human recombinant EGFR expressed in insect cells by time-resolved fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM3294(CHEMBL52765 | 4-N-(3-bromophenyl)quinazoline-4,6-d...)
Affinity DataIC50: 30nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cells after 1 hr by Western blotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50307934(N-(4-(3-Bromoanilino)quinazolin-6-yl)-2-(4-fluorop...)
Affinity DataIC50: 31nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cells after 1 hr by Western blotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50307935((2R,3S)-N-(4-(3-Bromoanilino)quinazolin-6-yl)-3-(p...)
Affinity DataIC50: 44nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cells after 8 hrs by Western blotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50307933(N-(4-(3-Bromoanilino)quinazolin-6-yl)-2-phenoxyace...)
Affinity DataIC50: 76nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cells after 1 hr by Western blotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50307932(N-(4-(3-Bromoanilino)quinazolin-6-yl)-2-(perfluoro...)
Affinity DataIC50: 78nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cells after 8 hrs by Western blotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50307932(N-(4-(3-Bromoanilino)quinazolin-6-yl)-2-(perfluoro...)
Affinity DataIC50: 84nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cells after 1 hr by Western blotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50307931(N-(4-(3-Bromoanilino)quinazolin-6-yl)-3-isopropyl-...)
Affinity DataIC50: 129nMAssay Description:Inhibition of human recombinant EGFR expressed in insect cells by time-resolved fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM4567(CHEMBL285063 | N-{4-[(3-bromophenyl)amino]quinazol...)
Affinity DataIC50: 152nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cells after 8 hrs by Western blotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50307934(N-(4-(3-Bromoanilino)quinazolin-6-yl)-2-(4-fluorop...)
Affinity DataIC50: 291nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cells after 8 hrs by Western blotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50307933(N-(4-(3-Bromoanilino)quinazolin-6-yl)-2-phenoxyace...)
Affinity DataIC50: 292nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cells after 8 hrs by Western blotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM3294(CHEMBL52765 | 4-N-(3-bromophenyl)quinazoline-4,6-d...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cells after 8 hrs by Western blotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed