Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50031406
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312718(torcetrapib | CHEMBL479527)
Affinity DataIC50: 3nMAssay Description:Inhibition of human plasma CETP assessed as [3H]cholesterol ester transfer after 18 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312714((S)-4-cyclohexyl-2-cyclopentyl-3-((S)-fluoro(4-(tr...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human plasma CETP assessed as [3H]cholesterol ester transfer after 18 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312715((S)-4'-cyclohexyl-3'-((S)-fluoro(4-(trifluoromethy...)
Affinity DataIC50: 17nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312718(torcetrapib | CHEMBL479527)
Affinity DataIC50: 18nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312718(torcetrapib | CHEMBL479527)
Affinity DataIC50: 20nMAssay Description:Inhibition of human plasma CETP assessed as cholesterol ester transfer after 24 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312716((S)-4'-cyclohexyl-2'-cyclopentyl-3'-((S)-fluoro(4-...)
Affinity DataIC50: 22nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312713((S)-4-cyclohexyl-3-((S)-fluoro(4-(trifluoromethyl)...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human plasma CETP assessed as [3H]cholesterol ester transfer after 18 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312720((S)-3'-((S)-fluoro(4-(trifluoromethyl)phenyl)methy...)
Affinity DataIC50: 24nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312714((S)-4-cyclohexyl-2-cyclopentyl-3-((S)-fluoro(4-(tr...)
Affinity DataIC50: 25nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312713((S)-4-cyclohexyl-3-((S)-fluoro(4-(trifluoromethyl)...)
Affinity DataIC50: 30nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312719(BAY-19-4789 | (S)-2-cyclopentyl-3-((S)-fluoro(4-(t...)
Affinity DataIC50: 31nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312730((S)-(4'-cyclohexyl-5'-hydroxy-2'-isopropyl-6',8'-d...)
Affinity DataIC50: 33nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312715((S)-4'-cyclohexyl-3'-((S)-fluoro(4-(trifluoromethy...)
Affinity DataIC50: 33nMAssay Description:Inhibition of human plasma CETP assessed as [3H]cholesterol ester transfer after 18 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312717((S)-4-cyclohexyl-2-cyclopentyl-7,7-dimethyl-3-(4-(...)
Affinity DataIC50: 39nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312714((S)-4-cyclohexyl-2-cyclopentyl-3-((S)-fluoro(4-(tr...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human plasma CETP assessed as cholesterol ester transfer after 24 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312732((S)-(4'-cyclohexyl-2'-cyclopentyl-5'-hydroxy-6',8'...)
Affinity DataIC50: 55nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312716((S)-4'-cyclohexyl-2'-cyclopentyl-3'-((S)-fluoro(4-...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human plasma CETP assessed as cholesterol ester transfer after 24 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312731((S)-(4-cyclohexyl-2-cyclopentyl-5-hydroxy-7,7-dime...)
Affinity DataIC50: 60nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312716((S)-4'-cyclohexyl-2'-cyclopentyl-3'-((S)-fluoro(4-...)
Affinity DataIC50: 62nMAssay Description:Inhibition of human plasma CETP assessed as [3H]cholesterol ester transfer after 18 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312711((S)-4'-cyclohexyl-3'-((S)-hydroxy(4-(trifluorometh...)
Affinity DataIC50: 70nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312729((S)-(4-cyclohexyl-5-hydroxy-2-isopropyl-7,7-dimeth...)
Affinity DataIC50: 70nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312728((S)-(2',4'-dicyclopentyl-5'-hydroxy-6',8'-dihydro-...)
Affinity DataIC50: 70nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312715((S)-4'-cyclohexyl-3'-((S)-fluoro(4-(trifluoromethy...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human plasma CETP assessed as cholesterol ester transfer after 24 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312713((S)-4-cyclohexyl-3-((S)-fluoro(4-(trifluoromethyl)...)
Affinity DataIC50: 75nMAssay Description:Inhibition of human plasma CETP assessed as cholesterol ester transfer after 24 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312709(trans-4-cyclohexyl-3-(hydroxy(4-(trifluoromethyl)p...)
Affinity DataIC50: 80nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312727((S)-(2,4-dicyclopentyl-5-hydroxy-7,7-dimethyl-5,6,...)
Affinity DataIC50: 90nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312712((S)-4'-cyclohexyl-2'-cyclopentyl-3'-((S)-hydroxy(4...)
Affinity DataIC50: 100nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312710(trans-4-cyclohexyl-2-cyclopentyl-3-(hydroxy(4-(tri...)
Affinity DataIC50: 100nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312717((S)-4-cyclohexyl-2-cyclopentyl-7,7-dimethyl-3-(4-(...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human plasma CETP assessed as cholesterol ester transfer after 24 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312725((S)-(2'-cyclopentyl-5'-hydroxy-4'-isopropyl-6',8'-...)
Affinity DataIC50: 300nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312705((S)-benzyl 4-(2-cyclopentyl-5-hydroxy-7,7-dimethyl...)
Affinity DataIC50: 500nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312724((S)-(2-cyclopentyl-5-hydroxy-4-isopropyl-7,7-dimet...)
Affinity DataIC50: 600nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312722((S)-(2'-cyclopentyl-5'-hydroxy-4'-propyl-6',8'-dih...)
Affinity DataIC50: 600nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312723((S)-(2-cyclopentyl-5-hydroxy-7,7-dimethyl-4-pentyl...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312733(((5S)-4-sec-butyl-2-cyclopentyl-5-hydroxy-7,7-dime...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312734((S)-(2-cyclopentyl-5-hydroxy-7,7-dimethyl-4-(2,2,2...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312726((S)-(2-cyclopentyl-4-cyclopropyl-5-hydroxy-7,7-dim...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312708((S)-(2-cyclopentyl-5-hydroxy-7,7-dimethyl-4-(pyrro...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312721((S)-(2-cyclopentyl-4-ethyl-5-hydroxy-7,7-dimethyl-...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312703((S)-(4-(chloromethyl)-2-cyclopentyl-5-hydroxy-7,7-...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312707((S)-(2-cyclopentyl-5-hydroxy-7,7-dimethyl-4-(piper...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312706((S)-(2-cyclopentyl-5-hydroxy-7,7-dimethyl-4-(piper...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312704((S)-ethyl 2-cyclopentyl-5-hydroxy-7,7-dimethyl-3-(...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed