Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50030917
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50304008(3-(4-Fluorophenyl)-2-(2-isopropylaminopyridin-4-yl...)
Affinity DataIC50: 38nMAssay Description:Inhibition of p38alpha-mediated ATF2 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50304016(4-(3-(4-Fluorophenyl)quinoxalin-2-yl)-N-isopropylp...)
Affinity DataIC50: 81nMAssay Description:Inhibition of p38alpha-mediated ATF2 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50304010(N-sec-Butyl-4-(3-(4-fluorophenyl)quinoxalin-2-yl)p...)
Affinity DataIC50: 114nMAssay Description:Inhibition of p38alpha-mediated ATF2 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50304013(4-(4-(3-(4-Fluorophenyl)quinoxalin-2-yl)pyridin-2-...)
Affinity DataIC50: 211nMAssay Description:Inhibition of p38alpha-mediated ATF2 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50304009(4-(3-(4-Fluorophenyl)-6,7-dimethylquinoxalin-2-yl)...)
Affinity DataIC50: 238nMAssay Description:Inhibition of p38alpha-mediated ATF2 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50304017(4-(4-(3-(4-Fluorophenyl)-6,7-dimethylquinoxalin-2-...)
Affinity DataIC50: 259nMAssay Description:Inhibition of p38alpha-mediated ATF2 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Eberhard-Karls-University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM13336(4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...)
Affinity DataIC50: 290nMAssay Description:Inhibition of JNK3 by nonradioactive JNK3 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50304011(2-(4-Fluorophenyl)-3-(2-isopropylaminopyridin-4-yl...)
Affinity DataIC50: 333nMAssay Description:Inhibition of p38alpha-mediated ATF2 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50304014(4-(6,7-Dichlor-3-(4-fluorophenyl)quinoxalin-2-yl)-...)
Affinity DataIC50: 412nMAssay Description:Inhibition of p38alpha-mediated ATF2 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50304015(4-(3-(4-Fluorophenyl)quinoxalin-2-yl)-N-((S)-1-phe...)
Affinity DataIC50: 431nMAssay Description:Inhibition of p38alpha-mediated ATF2 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50304012(4-(3-(4-Fluorophenyl)quinoxalin-2-yl)-N-((S)-3-met...)
Affinity DataIC50: 576nMAssay Description:Inhibition of p38alpha-mediated ATF2 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50304021(N-sec-Butyl-4-(3-(4-fluorophenyl)-6,7-dimethylquin...)
Affinity DataIC50: 595nMAssay Description:Inhibition of p38alpha-mediated ATF2 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50304018(4-(4-(6,7-Dichloro-3-(4-fluorophenyl)quinoxalin-2-...)
Affinity DataIC50: 608nMAssay Description:Inhibition of p38alpha-mediated ATF2 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50304029(4-(3-(4-Fluorophenyl)quinoxalin-2-yl)-N-isobutylpy...)
Affinity DataIC50: 642nMAssay Description:Inhibition of p38alpha-mediated ATF2 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50304015(4-(3-(4-Fluorophenyl)quinoxalin-2-yl)-N-((S)-1-phe...)
Affinity DataIC50: 720nMAssay Description:Inhibition of p38alpha-mediated ATF2 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50304012(4-(3-(4-Fluorophenyl)quinoxalin-2-yl)-N-((S)-3-met...)
Affinity DataIC50: 790nMAssay Description:Inhibition of p38alpha-mediated ATF2 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50304020(4-(3-(4-Fluorophenyl)-6,7-dimethylquinoxalin-2-yl)...)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of p38alpha-mediated ATF2 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50304022(N-Benzyl-4-(3-(4-fluorophenyl)-6,7-dimethylquinoxa...)
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of p38alpha-mediated ATF2 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50304024(4-(3-(4-Fluorophenyl)quinoxalin-2-yl)-N-((R)-3-met...)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of p38alpha-mediated ATF2 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50304025(2-(4-Fluorophenyl)-3-(pyridin-4-yl)quinoxaline | C...)
Affinity DataIC50: 3.15E+3nMAssay Description:Inhibition of p38alpha-mediated ATF2 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50304023(3-(4-Fluorophenyl)-2-(pyridin-4-yl)pyrido[2,3-b]py...)
Affinity DataIC50: 3.19E+3nMAssay Description:Inhibition of p38alpha-mediated ATF2 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50304026(2-(4-Fluorophenyl)-6,7-dimethyl-3-(pyridin-4-yl)qu...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of p38alpha-mediated ATF2 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Eberhard-Karls-University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50304016(4-(3-(4-Fluorophenyl)quinoxalin-2-yl)-N-isopropylp...)
Affinity DataIC50: 3.95E+3nMAssay Description:Inhibition of JNK3 by nonradioactive JNK3 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50304019(4-(3-(4-Fluorophenyl)quinoxalin-2-yl)-N-((R)-1-phe...)
Affinity DataIC50: 4.79E+3nMAssay Description:Inhibition of p38alpha-mediated ATF2 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50304027(3-(4-Fluorophenyl)-6-methoxy-2-(pyridin-4-yl)quino...)
Affinity DataIC50: 6.14E+3nMAssay Description:Inhibition of p38alpha-mediated ATF2 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50304028(4-(6,7-Dichloro-3-(4-fluorophenyl)quinoxalin-2-yl)...)
Affinity DataIC50: 9.46E+3nMAssay Description:Inhibition of p38alpha-mediated ATF2 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Eberhard-Karls-University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50304025(2-(4-Fluorophenyl)-3-(pyridin-4-yl)quinoxaline | C...)
Affinity DataIC50: 3.18E+4nMAssay Description:Inhibition of JNK3 by nonradioactive JNK3 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed