Compile Data Set for Download or QSAR
Report error Found 59 Enz. Inhib. hit(s) with all data for entry = 50039141
TargetProlyl endopeptidase(Rat)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50051495((S)-2-[(S)-2-(2-Hydroxy-acetyl)-pyrrolidine-1-carb...)
Affinity DataIC50: 0.830nMAssay Description:Inhibition of POP in rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50316822(3-cyclohexyl-N-((S)-1-oxo-3-phenyl-1-((S)-2-(piper...)
Affinity DataIC50: 1.05nMAssay Description:Inhibition of pig brain POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50316821(N-((S)-3-methyl-1-oxo-1-((S)-2-(piperidine-1-carbo...)
Affinity DataIC50: 1.05nMAssay Description:Inhibition of pig brain POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50193665(1-((2R,5S)-2-tert-butyl-5-(pyrrolidine-1-carbonyl)...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of pig brain POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Rat)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50316823(((2S,3aS,7aS)-1-((1R,2R)-2-phenylcyclopropanecarbo...)
Affinity DataIC50: 1.20nMAssay Description:inhibition of rat cortex POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50051539(4-Phenyl-1-[2-(pyrrolidine-1-carbonyl)-pyrrolidin-...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of pig brain POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50316817(4-phenyl-1-((S)-2-((S)-2-(5-phenylisoxazole-3-carb...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of pig POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Rat)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50316829(isoxazolidin-2-yl((2S,3aS,7aS)-1-((1R,2R)-2-phenyl...)
Affinity DataIC50: 2nMAssay Description:inhibition of rat cortex POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50051539(4-Phenyl-1-[2-(pyrrolidine-1-carbonyl)-pyrrolidin-...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of pig brain POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Rat)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50316830(((2S,3aS,7aS)-2-(1H-pyrrole-1-carbonyl)octahydro-1...)
Affinity DataIC50: 2.30nMAssay Description:inhibition of rat cortex POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Rat)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50316831((2,5-dihydro-1H-pyrrol-1-yl)((2S,3aS,7aS)-1-((1R,2...)
Affinity DataIC50: 2.40nMAssay Description:inhibition of rat cortex POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Rat)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50316832((2,3-dihydro-1H-pyrrol-1-yl)((2S,3aS,7aS)-1-((1R,2...)
Affinity DataIC50: 2.70nMAssay Description:inhibition of rat cortex POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Bovine)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50316842((S)-1-((S)-3-methyl-2-(4-phenylbutanamido)butanoyl...)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of bovine brain POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Mouse)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50051539(4-Phenyl-1-[2-(pyrrolidine-1-carbonyl)-pyrrolidin-...)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of mouse brain POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50284127(4-Phenyl-1-{(S)-2-[(S)-2-(thiazole-2-carbonyl)-pyr...)
Affinity DataIC50: 5nMAssay Description:Inhibition of pig kidney POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Rat)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50316841(((S)-2-((1R,2R)-2-phenylcyclopropanecarbonyl)-2-az...)
Affinity DataIC50: 5nMAssay Description:inhibition of rat cortex POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Rat)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50051539(4-Phenyl-1-[2-(pyrrolidine-1-carbonyl)-pyrrolidin-...)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of rat brain POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50284126((S)-1-[(S)-1-(4-Phenyl-butyryl)-pyrrolidine-2-carb...)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of pig kidney POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Rat)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50240498(1-[(S)-2-(Pyrrolidine-1-carbonyl)-pyrrolidin-1-yl]...)
Affinity DataIC50: 20nMAssay Description:Inhibition of POP in rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50051547((S)-2-(Pyrrolidine-1-carbonyl)-pyrrolidine-1-carbo...)
Affinity DataIC50: 29nMAssay Description:Inhibition of pig brain POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50316837(4-phenyl-1-(2-(pyrrolidine-1-carbonyl)cyclopent-1-...)
Affinity DataIC50: 230nMAssay Description:Inhibition of pig brain POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50075135((S)-4-phenyl-1-(3-(pyrrolidine-1-carbonyl)-3,4-dih...)
Affinity DataIC50: 550nMAssay Description:Inhibition of human platelet POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Bovine)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50051539(4-Phenyl-1-[2-(pyrrolidine-1-carbonyl)-pyrrolidin-...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of bovine brain POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50242173((2S,3S,4S,5R,6S)-6-(5,6-dihydroxy-4-oxo-2-phenyl-4...)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of human recombinant POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50316826((S)-benzyl 2-((S)-2-(hydroxymethyl)pyrrolidine-1-c...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of POP in human PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Bovine)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50316826((S)-benzyl 2-((S)-2-(hydroxymethyl)pyrrolidine-1-c...)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of bovine brain POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50316824(4-(4-chlorophenyl)-8-(ethoxycarbonyl)-5-methyl-2,3...)
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of human recombinant POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50051495((S)-2-[(S)-2-(2-Hydroxy-acetyl)-pyrrolidine-1-carb...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetXaa-Pro dipeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50051495((S)-2-[(S)-2-(2-Hydroxy-acetyl)-pyrrolidine-1-carb...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of prolidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetLysosomal Pro-X carboxypeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50051495((S)-2-[(S)-2-(2-Hydroxy-acetyl)-pyrrolidine-1-carb...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of carboxypeptidase PMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetCytosol aminopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50051495((S)-2-[(S)-2-(2-Hydroxy-acetyl)-pyrrolidine-1-carb...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of proline iminopeptidase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50203126(Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...)
Affinity DataIC50: 1.45E+5nMAssay Description:Inhibition of human recombinant POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Bovine)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50316838((S)-4-phenyl-1-(2-(pyrrolidin-1-ylmethyl)pyrrolidi...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of bovine brain POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50155838((S)-1-((S)-1-(4-phenylbutanoyl)pyrrolidine-2-carbo...)
Affinity DataKi:  0.0230nMAssay Description:Inhibition of pig POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Bovine)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50038879(JTP-4819 | CHEMBL79993 | (S)-2-(2-Formyl-pyrrolidi...)
Affinity DataKi:  0.210nMAssay Description:Inhibition of bovine brain POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Mouse)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50038879(JTP-4819 | CHEMBL79993 | (S)-2-(2-Formyl-pyrrolidi...)
Affinity DataKi:  0.350nMAssay Description:Inhibition of mouse brain POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50170682((S)-1-((S)-1-(3-((S)-2-(cyclopentanecarbonyl)pyrro...)
Affinity DataKi:  0.360nMAssay Description:Inhibition of pig brain POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Flavobacterium meningosepticum)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50038879(JTP-4819 | CHEMBL79993 | (S)-2-(2-Formyl-pyrrolidi...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of Flavobacterium meningosepticum POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Rat)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50038881([2-(8-Dimethylamino-octylsulfanyl)-6-isopropyl-pyr...)
Affinity DataKi:  0.950nMAssay Description:Inhibition of POP in rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Rat)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50316818(((2S,3aS,7aS)-1-((1R,2R)-2-phenylcyclopropanecarbo...)
Affinity DataKi:  1.30nMAssay Description:inhibition of rat cortex POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50316818(((2S,3aS,7aS)-1-((1R,2R)-2-phenylcyclopropanecarbo...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of human POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50200729((R)-1-(2-(2,5-dichlorobenzamido)acetyl)pyrrolidin-...)
Affinity DataKi:  2.20nMAssay Description:Inhibition of recombinant POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Mouse)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50316840((R)-benzyl 2-((S)-2-formylpyrrolidine-1-carbonyl)i...)
Affinity DataKi:  2.40nMAssay Description:Inhibition of mouse brain POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Mouse)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50279826((1S,2S)-benzyl 2-((S)-2-formylpyrrolidine-1-carbon...)
Affinity DataKi:  3nMAssay Description:Inhibition of mouse brain POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Bovine)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50316839((S)-benzyl 2-((S)-2-formylpyrrolidine-1-carbonyl)-...)
Affinity DataKi:  3.40nMAssay Description:Inhibition of bovine brain POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Rat)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50316819((S)-1-(4-(4-chlorobenzylamino)-4-oxobutanoyl)pyrro...)
Affinity DataKi:  12nMAssay Description:inhibition of rat cortex POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50200730((R)-1-(2-acetamidoacetyl)pyrrolidin-2-ylboronic ac...)
Affinity DataKi:  23nMAssay Description:Inhibition of recombinant FAPalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50200729((R)-1-(2-(2,5-dichlorobenzamido)acetyl)pyrrolidin-...)
Affinity DataKi:  29nMAssay Description:Inhibition of recombinant FAPalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Mouse)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50316836((9H-fluoren-9-yl)methyl(S)-1-((S)-2-cyanopyrrolidi...)
Affinity DataKi:  33nMAssay Description:Inhibition of mouse brain POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Bovine)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50316835((S)-benzyl 2-(thiazolidine-3-carbonyl)pyrrolidine-...)
Affinity DataKi:  39nMAssay Description:Inhibition of bovine brain POPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2012
Entry Details Article
PubMed
Displayed 1 to 50 (of 59 total ) | Next | Last >>
Jump to: