Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50031212
TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309015(N-(5-chloro-2-((5'-chloro-3,3'-difluoro-2'-(5-meth...)
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells pretreated with IL1-beta assessed as inhibition of DAKD-induced calcium mobilizati...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309011(N-(4-((5'-chloro-3,3'-difluoro-2'-(5-methyl-1,2,4-...)
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells pretreated with IL1-beta assessed as inhibition of DAKD-induced calcium mobilizati...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309021(N-(2-((5'-chloro-3,3'-difluoro-2'-(5-methyl-1,2,4-...)
Affinity DataIC50: 0.700nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells pretreated with IL1-beta assessed as inhibition of DAKD-induced calcium mobilizati...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309025(N-(4-((5'-chloro-3,3'-difluoro-2'-(5-methyl-1,2,4-...)
Affinity DataIC50: 1nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells pretreated with IL1-beta assessed as inhibition of DAKD-induced calcium mobilizati...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309014(N-(2-((5'-chloro-3,3'-difluoro-2'-(5-methyl-1,2,4-...)
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells pretreated with IL1-beta assessed as inhibition of DAKD-induced calcium mobilizati...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309023(N-(2-((5'-chloro-3,3'-difluoro-2'-(5-methyl-1,2,4-...)
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells pretreated with IL1-beta assessed as inhibition of DAKD-induced calcium mobilizati...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309026(N-(4-((5'-chloro-3,3'-difluoro-2'-(5-methyl-1,2,4-...)
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells pretreated with IL1-beta assessed as inhibition of DAKD-induced calcium mobilizati...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309024(N-(3-((5'-chloro-3,3'-difluoro-2'-(5-methyl-1,2,4-...)
Affinity DataIC50: 3.5nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells pretreated with IL1-beta assessed as inhibition of DAKD-induced calcium mobilizati...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309012(N-(2-((5'-chloro-3,3'-difluoro-2'-(5-methyl-1,2,4-...)
Affinity DataIC50: 4.60nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells pretreated with IL1-beta assessed as inhibition of DAKD-induced calcium mobilizati...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309016(N-(4-((5'-chloro-3,3'-difluoro-2'-(5-methyl-1,2,4-...)
Affinity DataIC50: 7.70nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells pretreated with IL1-beta assessed as inhibition of DAKD-induced calcium mobilizati...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309022(N-(2-((5'-chloro-3,3'-difluoro-2'-(5-methyl-1,2,4-...)
Affinity DataIC50: 85nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells pretreated with IL1-beta assessed as inhibition of DAKD-induced calcium mobilizati...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309013(N-(2-((5'-chloro-3,3'-difluoro-2'-(5-methyl-1,2,4-...)
Affinity DataIC50: 180nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells pretreated with IL1-beta assessed as inhibition of DAKD-induced calcium mobilizati...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309020(methyl 4'-((1H-benzo[d]imidazol-2-ylamino)methyl)-...)
Affinity DataIC50: 3.50E+3nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells pretreated with IL1-beta assessed as inhibition of DAKD-induced calcium mobilizati...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309019(methyl 3,3'-difluoro-4'-((1-oxoisoindolin-2-yl)met...)
Affinity DataIC50: 6.10E+3nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells pretreated with IL1-beta assessed as inhibition of DAKD-induced calcium mobilizati...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309017(methyl 4'-(acetamidomethyl)-3,3'-difluorobiphenyl-...)
Affinity DataIC50: 3.50E+4nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells pretreated with IL1-beta assessed as inhibition of DAKD-induced calcium mobilizati...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandPNGBDBM50309018(methyl 3,3'-difluoro-4'-((2-oxopyrrolidin-1-yl)met...)
Affinity DataIC50: 4.20E+4nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells pretreated with IL1-beta assessed as inhibition of DAKD-induced calcium mobilizati...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed