Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50031055
TargetCoagulation factor X(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50228676((S)-2-(5-chlorothiophen-2-yl)-N-(1-(4-(2-((dimethy...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306153((S)-2-(5-chlorothiophen-2-yl)-N-(1-(3-fluoro-2'-(m...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306146(2-(5-chlorothiophen-2-yl)-N-((S)-1-(4-((S)-1-(dime...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor X(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306138(N-((3S)-1-(4-(1-(azetidin-1-yl)ethyl)-2-fluorophen...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306142(6-chloro-N-((3S)-1-(4-(1-(ethyl(methyl)amino)ethyl...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306143(6-chloro-N-((S)-1-(4-((S)-1-(dimethylamino)ethyl)-...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306140(6-chloro-N-((3S)-1-(2-fluoro-4-(1-(isopropylamino)...)
Affinity DataKi:  1nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306146(2-(5-chlorothiophen-2-yl)-N-((S)-1-(4-((S)-1-(dime...)
Affinity DataKi:  1nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor X(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306148((S)-4-(3-(2-(5-chlorothiophen-2-yl)vinylsulfonamid...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor X(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306143(6-chloro-N-((S)-1-(4-((S)-1-(dimethylamino)ethyl)-...)
Affinity DataKi:  2nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306147(2-(5-chlorothiophen-2-yl)-N-((S)-1-(4-((R)-1-(dime...)
Affinity DataKi:  2nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306144(6-chloro-N-((S)-1-(4-((R)-1-(dimethylamino)ethyl)-...)
Affinity DataKi:  2nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306141(6-chloro-N-((3S)-1-(4-(1-(ethylamino)ethyl)-2-fluo...)
Affinity DataKi:  2nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306137(6-chloro-N-((3S)-1-(2-fluoro-4-(1-(pyrrolidin-1-yl...)
Affinity DataKi:  2nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306136(6-chloro-N-((3S)-1-(2-fluoro-4-(1-(piperidin-1-yl)...)
Affinity DataKi:  2nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306134(6-chloro-N-((S)-1-(2-fluoro-4-((S)-1-(methylamino)...)
Affinity DataKi:  2nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306135(6-chloro-N-((S)-1-(2-fluoro-4-((R)-1-(methylamino)...)
Affinity DataKi:  4nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM17643((E)-2-(5-chlorothiophen-2-yl)-N-[(3S)-1-[(2S)-1-(m...)
Affinity DataKi:  4nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306145(6-chloro-N-((3S)-1-(4-(1-(dimethylamino)ethyl)-2-f...)
Affinity DataKi:  5nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306139(6-chloro-N-((3S)-1-(2-fluoro-4-(1-(isopropyl(methy...)
Affinity DataKi:  5nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306150((S)-4-(3-(2-(5-chlorothiophen-2-yl)vinylsulfonamid...)
Affinity DataKi:  5.10nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306151((S)-N-(1-(4-acetyl-2-fluorophenyl)-2-oxopyrrolidin...)
Affinity DataKi:  6nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306152((S)-2-(5-chlorothiophen-2-yl)-N-(1-(2-fluoro-4-(pr...)
Affinity DataKi:  6.20nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50306149((S)-4-(3-(2-(5-chlorothiophen-2-yl)vinylsulfonamid...)
Affinity DataKi:  35nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed