Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50031187
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50308674(N-{4-[3-(4-Ethyldimethylsilanylbenzyl)thioureidome...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as intracellular 45Ca2+ influx by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50308675(N-{4-[3-(4-Triethylsilanylbenzyl)thioureidomethyl]...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as intracellular 45Ca2+ influx by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50308680(N-{4-[3-(4-Trimethylsilanylbenzyl)thioureidomethyl...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as intracellular 45Ca2+ influx by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM20315(3-[(4-tert-butylphenyl)methyl]-1-[(4-methanesulfon...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as intracellular 45Ca2+ influx by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50308676((R)-N-(4-{1-[3-(4-Trimethylsilanylbenzyl)thioureid...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as intracellular 45Ca2+ influx by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50308677((R)-N-[4-(1-{3-[4-(Ethyldimethylsilanyl)benzyl]thi...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as intracellular 45Ca2+ influx by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM20321(JYL1421 | CHEMBL388824 | 3-[(4-tert-butylphenyl)me...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as intracellular 45Ca2+ influx by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50308678((R)-N-(4-{1-[3-(4-Triethylsilanylbenzyl)thioureido...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as intracellular 45Ca2+ influx by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50308679(N-{2-Fluoro-4-[3-(4-trimethylsilanylbenzyl)thioure...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as intracellular 45Ca2+ influx by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50142759(N-(4-{(R)-1-[3-(4-tert-Butyl-benzyl)-thioureido]-e...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as intracellular 45Ca2+ influx by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM20321(JYL1421 | CHEMBL388824 | 3-[(4-tert-butylphenyl)me...)
Affinity DataIC50: 40nMAssay Description:Antagonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as reduction of capsaicin-stimulated intracellular 45Ca2+ influx by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50142759(N-(4-{(R)-1-[3-(4-tert-Butyl-benzyl)-thioureido]-e...)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as reduction of capsaicin-stimulated intracellular 45Ca2+ influx by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM20315(3-[(4-tert-butylphenyl)methyl]-1-[(4-methanesulfon...)
Affinity DataIC50: 110nMAssay Description:Antagonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as reduction of capsaicin-stimulated intracellular 45Ca2+ influx by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50308680(N-{4-[3-(4-Trimethylsilanylbenzyl)thioureidomethyl...)
Affinity DataIC50: 150nMAssay Description:Antagonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as reduction of capsaicin-stimulated intracellular 45Ca2+ influx by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50308679(N-{2-Fluoro-4-[3-(4-trimethylsilanylbenzyl)thioure...)
Affinity DataIC50: 160nMAssay Description:Antagonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as reduction of capsaicin-stimulated intracellular 45Ca2+ influx by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50308676((R)-N-(4-{1-[3-(4-Trimethylsilanylbenzyl)thioureid...)
Affinity DataIC50: 210nMAssay Description:Antagonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as reduction of capsaicin-stimulated intracellular 45Ca2+ influx by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50308677((R)-N-[4-(1-{3-[4-(Ethyldimethylsilanyl)benzyl]thi...)
Affinity DataIC50: 670nMAssay Description:Antagonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as reduction of capsaicin-stimulated intracellular 45Ca2+ influx by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50308674(N-{4-[3-(4-Ethyldimethylsilanylbenzyl)thioureidome...)
Affinity DataIC50: 1.20E+3nMAssay Description:Antagonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as reduction of capsaicin-stimulated intracellular 45Ca2+ influx by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50308678((R)-N-(4-{1-[3-(4-Triethylsilanylbenzyl)thioureido...)
Affinity DataIC50: 1.50E+3nMAssay Description:Antagonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as reduction of capsaicin-stimulated intracellular 45Ca2+ influx by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50308675(N-{4-[3-(4-Triethylsilanylbenzyl)thioureidomethyl]...)
Affinity DataIC50: 3.10E+3nMAssay Description:Antagonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as reduction of capsaicin-stimulated intracellular 45Ca2+ influx by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed