Compile Data Set for Download or QSAR
Report error Found 51 Enz. Inhib. hit(s) with all data for entry = 3488
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35554(thiophene scaffold, 21)
Affinity DataIC50: 9nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35570(1H-benzo[de]isoquinoline-1,3(2H)-dione, 19)
Affinity DataIC50: 14nM EC50:  2.20E+3nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
LigandPNGBDBM35554(thiophene scaffold, 21)
Affinity DataIC50: 16nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35563(1H-benzo[de]isoquinoline-1,3(2H)-dione, 12)
Affinity DataIC50: 19nM EC50:  3.80E+3nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
LigandPNGBDBM35553(1H-benzo[de]isoquinoline-1,3(2H)-dione, 1)
Affinity DataIC50: 20nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35553(1H-benzo[de]isoquinoline-1,3(2H)-dione, 1)
Affinity DataIC50: 20nM EC50:  7.10E+3nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35560(1H-benzo[de]isoquinoline-1,3(2H)-dione, 9)
Affinity DataIC50: 24nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35558(1H-benzo[de]isoquinoline-1,3(2H)-dione, 7)
Affinity DataIC50: 29nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35569(1H-benzo[de]isoquinoline-1,3(2H)-dione, 18)
Affinity DataIC50: 30nM EC50:  1.90E+3nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
LigandPNGBDBM35554(thiophene scaffold, 21)
Affinity DataIC50: 40nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35571(cis-isomers | 1H-benzo[de]isoquinoline-1,3(2H)-dio...)
Affinity DataIC50: 42nM EC50:  3.80E+3nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35570(1H-benzo[de]isoquinoline-1,3(2H)-dione, 19)
Affinity DataIC50: 43nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35553(1H-benzo[de]isoquinoline-1,3(2H)-dione, 1)
Affinity DataIC50: 64nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35567(1H-benzo[de]isoquinoline-1,3(2H)-dione, 16)
Affinity DataIC50: 66nM EC50: >5.00E+4nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
LigandPNGBDBM35553(1H-benzo[de]isoquinoline-1,3(2H)-dione, 1)
Affinity DataIC50: 78nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35566(1H-benzo[de]isoquinoline-1,3(2H)-dione, 15)
Affinity DataIC50: 90nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
LigandPNGBDBM35554(thiophene scaffold, 21)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35571(cis-isomers | 1H-benzo[de]isoquinoline-1,3(2H)-dio...)
Affinity DataIC50: 110nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35569(1H-benzo[de]isoquinoline-1,3(2H)-dione, 18)
Affinity DataIC50: 120nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35567(1H-benzo[de]isoquinoline-1,3(2H)-dione, 16)
Affinity DataIC50: 120nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35560(1H-benzo[de]isoquinoline-1,3(2H)-dione, 9)
Affinity DataIC50: 124nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35568(1H-benzo[de]isoquinoline-1,3(2H)-dione, 17)
Affinity DataIC50: 130nM EC50:  2.00E+3nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35566(1H-benzo[de]isoquinoline-1,3(2H)-dione, 15)
Affinity DataIC50: 130nM EC50:  1.10E+4nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35553(1H-benzo[de]isoquinoline-1,3(2H)-dione, 1)
Affinity DataIC50: 180nM EC50:  1.10E+4nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35558(1H-benzo[de]isoquinoline-1,3(2H)-dione, 7)
Affinity DataIC50: 185nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35557(1H-benzo[de]isoquinoline-1,3(2H)-dione, 6)
Affinity DataIC50: 190nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35563(1H-benzo[de]isoquinoline-1,3(2H)-dione, 12)
Affinity DataIC50: 200nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35564(1H-benzo[de]isoquinoline-1,3(2H)-dione, 13)
Affinity DataIC50: 200nM EC50: >5.00E+4nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35557(1H-benzo[de]isoquinoline-1,3(2H)-dione, 6)
Affinity DataIC50: 300nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35568(1H-benzo[de]isoquinoline-1,3(2H)-dione, 17)
Affinity DataIC50: 400nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35553(1H-benzo[de]isoquinoline-1,3(2H)-dione, 1)
Affinity DataIC50: 490nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35559(1H-benzo[de]isoquinoline-1,3(2H)-dione, 8)
Affinity DataIC50: 500nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
LigandPNGBDBM35554(thiophene scaffold, 21)
Affinity DataIC50: 500nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
LigandPNGBDBM35553(1H-benzo[de]isoquinoline-1,3(2H)-dione, 1)
Affinity DataIC50: 500nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35553(1H-benzo[de]isoquinoline-1,3(2H)-dione, 1)
Affinity DataIC50: 540nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35553(1H-benzo[de]isoquinoline-1,3(2H)-dione, 1)
Affinity DataIC50: 760nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35553(1H-benzo[de]isoquinoline-1,3(2H)-dione, 1)
Affinity DataIC50: 770nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35561(benzo[de]isoquinolinone, 10)
Affinity DataIC50: 850nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
LigandPNGBDBM35553(1H-benzo[de]isoquinoline-1,3(2H)-dione, 1)
Affinity DataIC50: 1.00E+3nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35565(1H-benzo[de]isoquinoline-1,3(2H)-dione, 14)
Affinity DataIC50: 1.60E+3nM EC50: >5.00E+4nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35555(1H-benzo[de]isoquinoline-1,3(2H)-dione, 4)
Affinity DataIC50: 1.70E+3nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35559(1H-benzo[de]isoquinoline-1,3(2H)-dione, 8)
Affinity DataIC50: 1.80E+3nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35561(benzo[de]isoquinolinone, 10)
Affinity DataIC50: 3.50E+3nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35554(thiophene scaffold, 21)
Affinity DataIC50: 1.00E+4nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35565(1H-benzo[de]isoquinoline-1,3(2H)-dione, 14)
Affinity DataIC50: 5.00E+4nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35562(benzo[de]isoquinoline, 11)
Affinity DataIC50: 5.00E+4nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35564(1H-benzo[de]isoquinoline-1,3(2H)-dione, 13)
Affinity DataIC50: 5.00E+4nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35562(benzo[de]isoquinoline, 11)
Affinity DataIC50: 5.00E+4nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35556(1H-benzo[de]isoquinoline-1,3(2H)-dione, 5)
Affinity DataIC50: 5.00E+4nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Irbm, Mrl Rome

LigandPNGBDBM35555(1H-benzo[de]isoquinoline-1,3(2H)-dione, 4)
Affinity DataIC50: 5.00E+4nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2009
Entry Details Article
PubMed
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