Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50030964
TargetLysophosphatidic acid receptor 2(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50271765(4,4'-(4,4'-(1,3-phenylenebis(oxy))bis(4,1-phenylen...)
Affinity DataIC50: 9nMAssay Description:Antagonist activity at LPA2 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 2(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50271763(3-[3-(3-Carboxy-acryloylamino)-phenylcarbamoyl]-ac...)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at LPA2 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50271625(2-(2-(2-aminoacetamido)-3-(2,4-dinitrophenylthio)p...)
Affinity DataIC50: 24nMAssay Description:Antagonist activity at LPA3 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50271701(2,6-bis(3-carboxyacrylamido)benzoic acid | 4,4'-(2...)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at LPA3 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50304580(2-(3-(4-nitrophenoxy)phenyl)-1,3-dioxoisoindoline-...)
Affinity DataIC50: 94nMAssay Description:Antagonist activity at LPA1 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50271763(3-[3-(3-Carboxy-acryloylamino)-phenylcarbamoyl]-ac...)
Affinity DataIC50: 220nMAssay Description:Antagonist activity at LPA1 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 2(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50271701(2,6-bis(3-carboxyacrylamido)benzoic acid | 4,4'-(2...)
Affinity DataIC50: 355nMAssay Description:Antagonist activity at LPA2 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 5(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50304580(2-(3-(4-nitrophenoxy)phenyl)-1,3-dioxoisoindoline-...)
Affinity DataIC50: 463nMAssay Description:Antagonist activity at LPA5 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50304581(2-(1,3-dioxo-5-(p-tolyloxy)isoindolin-2-yl)acetic ...)
Affinity DataIC50: 609nMAssay Description:Antagonist activity at LPA1 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50304580(2-(3-(4-nitrophenoxy)phenyl)-1,3-dioxoisoindoline-...)
Affinity DataIC50: 752nMAssay Description:Antagonist activity at LPA3 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50271765(4,4'-(4,4'-(1,3-phenylenebis(oxy))bis(4,1-phenylen...)
Affinity DataIC50: 1.23E+3nMAssay Description:Antagonist activity at LPA3 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50304581(2-(1,3-dioxo-5-(p-tolyloxy)isoindolin-2-yl)acetic ...)
Affinity DataIC50: 2.99E+3nMAssay Description:Antagonist activity at LPA3 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50304582([5-(3-nitrophenoxy)-1,3-dioxo-1,3-dihydro-2-isoind...)
Affinity DataIC50: 4.50E+3nMAssay Description:Antagonist activity at LPA3 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50271765(4,4'-(4,4'-(1,3-phenylenebis(oxy))bis(4,1-phenylen...)
Affinity DataIC50: 2.74E+4nMAssay Description:Antagonist activity at LPA1 receptor expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50304580(2-(3-(4-nitrophenoxy)phenyl)-1,3-dioxoisoindoline-...)
Affinity DataKi:  48nMAssay Description:Binding affinity to LPA1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50304580(2-(3-(4-nitrophenoxy)phenyl)-1,3-dioxoisoindoline-...)
Affinity DataKi:  230nMAssay Description:Binding affinity to LPA3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 5(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50304580(2-(3-(4-nitrophenoxy)phenyl)-1,3-dioxoisoindoline-...)
Affinity DataKi:  292nMAssay Description:Binding affinity to LPA5More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50304581(2-(1,3-dioxo-5-(p-tolyloxy)isoindolin-2-yl)acetic ...)
Affinity DataKi:  311nMAssay Description:Binding affinity to LPA1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50304581(2-(1,3-dioxo-5-(p-tolyloxy)isoindolin-2-yl)acetic ...)
Affinity DataKi:  1.08E+3nMAssay Description:Binding affinity to LPA3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed