Compile Data Set for Download or QSAR
Report error Found 58 Enz. Inhib. hit(s) with all data for entry = 50038989
TargetSodium/glucose cotransporter 2(Mouse)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302603((2S,3R,4R,5S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl...)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302603((2S,3R,4R,5S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl...)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302617((2S,3R,4R,5S)-2-[4-Chloro-3-(4-hydroxy-benzyl)-phe...)
Affinity DataIC50: 8nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302616((2S,3R,4R,5S)-2-(4-Chloro-3-(4-(2-hydroxyethoxy)be...)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302625((2S,3R,4R,5S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl...)
Affinity DataIC50: 15nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302625((2S,3R,4R,5S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl...)
Affinity DataIC50: 15nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302615((2S,3R,4R,5S)-2-{4-Chloro-3-[4-(2-methoxy-ethoxy)-...)
Affinity DataIC50: 16nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302624((2S,3R,4R,5S)-2-[4-Chloro-3-(4-ethoxy-benzyl)-phen...)
Affinity DataIC50: 19nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302623((2S,3R,4R,5S)-2-(3-(4-Ethoxybenzyl)-4-methylphenyl...)
Affinity DataIC50: 23nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302609((2S,3R,4R,5S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl...)
Affinity DataIC50: 23nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302603((2S,3R,4R,5S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302603((2S,3R,4R,5S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302603((2S,3R,4R,5S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302617((2S,3R,4R,5S)-2-[4-Chloro-3-(4-hydroxy-benzyl)-phe...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302616((2S,3R,4R,5S)-2-(4-Chloro-3-(4-(2-hydroxyethoxy)be...)
Affinity DataIC50: 36nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302609((2S,3R,4R,5S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl...)
Affinity DataIC50: 36nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302615((2S,3R,4R,5S)-2-{4-Chloro-3-[4-(2-methoxy-ethoxy)-...)
Affinity DataIC50: 45nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302623((2S,3R,4R,5S)-2-(3-(4-Ethoxybenzyl)-4-methylphenyl...)
Affinity DataIC50: 55nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302619([2-Chloro-5-((2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-m...)
Affinity DataIC50: 57nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302624((2S,3R,4R,5S)-2-[4-Chloro-3-(4-ethoxy-benzyl)-phen...)
Affinity DataIC50: 58nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302613((2S,3R,4R,5S)-2-(4-Chloro-3-(4-(thiazol-2-yloxy)be...)
Affinity DataIC50: 60nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302614((2R,3S,4S,5R)-2-(4-Chloro-3-(4-((S)-1-methylpyrrol...)
Affinity DataIC50: 92nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302621((2S,3R,4R,5S)-2-(4-Chloro-3-(4-methoxyphenylthio)p...)
Affinity DataIC50: 100nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302604((3S,4R,5R,6S)-6-[4-Chloro-3-(4-ethoxy-benzyl)-phen...)
Affinity DataIC50: 100nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302619([2-Chloro-5-((2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-m...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302613((2S,3R,4R,5S)-2-(4-Chloro-3-(4-(thiazol-2-yloxy)be...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302614((2R,3S,4S,5R)-2-(4-Chloro-3-(4-((S)-1-methylpyrrol...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302621((2S,3R,4R,5S)-2-(4-Chloro-3-(4-methoxyphenylthio)p...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM20875(CHEMBL245067 | JMC511145 Compound 1 | 1-(2,4-dihyd...)
Affinity DataIC50: 210nMAssay Description:Inhibition of human SGLT1 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302606((2S,3R,4R,5R)-2-[4-Chloro-3-(4-ethoxy-benzyl)-phen...)
Affinity DataIC50: 220nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302605((2S,3R,4R,5S)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl...)
Affinity DataIC50: 220nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302622((2S,3R,4R,5S)-2-(3-(4-Ethoxybenzyl)phenyl)-6-metho...)
Affinity DataIC50: 220nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302603((2S,3R,4R,5S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl...)
Affinity DataIC50: 280nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302603((2S,3R,4R,5S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl...)
Affinity DataIC50: 280nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302604((3S,4R,5R,6S)-6-[4-Chloro-3-(4-ethoxy-benzyl)-phen...)
Affinity DataIC50: 280nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302612(O-4-(2-Chloro-5-((2S,3R,4R,5S)-3,4,5-trihydroxy-6-...)
Affinity DataIC50: 330nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302608((3S,4R,5R,6S)-2-(benzyloxy)-6-(4-chloro-3-(4-ethox...)
Affinity DataIC50: 330nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302625((2S,3R,4R,5S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl...)
Affinity DataIC50: 420nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302625((2S,3R,4R,5S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl...)
Affinity DataIC50: 420nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302605((2S,3R,4R,5S)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl...)
Affinity DataIC50: 590nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302606((2S,3R,4R,5R)-2-[4-Chloro-3-(4-ethoxy-benzyl)-phen...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302608((3S,4R,5R,6S)-2-(benzyloxy)-6-(4-chloro-3-(4-ethox...)
Affinity DataIC50: 620nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302612(O-4-(2-Chloro-5-((2S,3R,4R,5S)-3,4,5-trihydroxy-6-...)
Affinity DataIC50: 740nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM20880(CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...)
Affinity DataIC50: 810nMAssay Description:Inhibition of human SGLT1 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302622((2S,3R,4R,5S)-2-(3-(4-Ethoxybenzyl)phenyl)-6-metho...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302620((2S,3R,4R,5S)-2-(4-Chloro-3-(4-ethoxyphenoxy)pheny...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302618((2S,3R,4R,5S)-2-(4'-Ethoxybiphenyl-4-yl)-6-methoxy...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302607((2S,3R,4R,5S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302620((2S,3R,4R,5S)-2-(4-Chloro-3-(4-ethoxyphenoxy)pheny...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302603((2S,3R,4R,5S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human SGLT1 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
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