Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50030846
LigandPNGBDBM50302574(N-butyl-N-ethyl-1-mesityl-3,6-dimethyl-1H-pyrazolo...)
Affinity DataKi:  9nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302593(1-(4-methoxy-2-methylphenyl)-N-(2-methoxyethyl)-3,...)
Affinity DataKi:  13nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302599(1-(2,6-dimethoxypyridin-3-yl)-N-(2-methoxyethyl)-3...)
Affinity DataKi:  17nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302573(N-(heptan-4-yl)-1-(4-methoxy-2-methylphenyl)-6-met...)
Affinity DataKi:  32nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302582(N-(heptan-4-yl)-1-(4-methoxy-2-methylphenyl)-3,6-d...)
Affinity DataKi:  35nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302581(1-(4-methoxy-2-methylphenyl)-3,6-dimethyl-N-(penta...)
Affinity DataKi:  42nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302598(1-(6-methoxy-2-methylpyridin-3-yl)-N-(2-methoxyeth...)
Affinity DataKi:  43nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302594(1-(2,4-dimethoxyphenyl)-N-(2-methoxyethyl)-3,6-dim...)
Affinity DataKi:  74nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302577((2R)-2-(1-(4-methoxy-2-methylphenyl)-3,6-dimethyl-...)
Affinity DataKi:  76nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302589(N-(1-(4-methoxy-2-methylphenyl)-3,6-dimethyl-1H-py...)
Affinity DataKi:  84nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302584(1-(4-methoxy-2-methylphenyl)-6-methyl-N-(pentan-3-...)
Affinity DataKi:  85nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302595(4-(4-((2-methoxyethyl)(propyl)amino)-3,6-dimethyl-...)
Affinity DataKi:  101nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302602(N-ethyl-1-(4-methoxy-2-methylphenyl)-N-(2-methoxye...)
Affinity DataKi:  117nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302590(N-(1-(4-methoxy-2-methylphenyl)-3,6-dimethyl-1H-py...)
Affinity DataKi:  124nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302586(2-((1-(4-methoxy-2-methylphenyl)-3,6-dimethyl-1H-p...)
Affinity DataKi:  129nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302583(1-(4-methoxy-2-methylphenyl)-N-(1-methoxyhexan-3-y...)
Affinity DataKi:  132nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302575(1-(4-methoxy-2-methylphenyl)-N-((S)-1-methoxybutan...)
Affinity DataKi:  135nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302600(1-(6-(dimethylamino)-2,4-dimethylpyridin-3-yl)-N-(...)
Affinity DataKi:  183nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302585(1-(4-methoxy-2-methylphenyl)-N,N-bis(2-methoxyethy...)
Affinity DataKi:  193nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302576(1-(4-methoxy-2-methylphenyl)-N-((R)-1-methoxybutan...)
Affinity DataKi:  210nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302597(4-(4-((2-methoxyethyl)(propyl)amino)-3,6-dimethyl-...)
Affinity DataKi:  275nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302591(1-(4-methoxy-2-methylphenyl)-3,6-dimethyl-N-(2-((p...)
Affinity DataKi:  400nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302578((2S)-2-(1-(4-methoxy-2-methylphenyl)-3,6-dimethyl-...)
Affinity DataKi:  574nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302601(5-(4-((2-methoxyethyl)(propyl)amino)-3,6-dimethyl-...)
Affinity DataKi:  577nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302579((2S)-2-(1-(4-methoxy-2-methylphenyl)-3,6-dimethyl-...)
Affinity DataKi:  620nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302596(4-(4-((2-methoxyethyl)(propyl)amino)-3,6-dimethyl-...)
Affinity DataKi:  632nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302588(N-(1-(4-methoxy-2-methylphenyl)-3,6-dimethyl-1H-py...)
Affinity DataKi:  996nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302580((2R)-2-(1-(4-methoxy-2-methylphenyl)-3,6-dimethyl-...)
Affinity DataKi:  1.13E+3nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302587(2-((1-(4-methoxy-2-methylphenyl)-3,6-dimethyl-1H-p...)
Affinity DataKi:  1.41E+3nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302592(1-(4-methoxy-2-methylphenyl)-3,6-dimethyl-N-(5-((p...)
Affinity DataKi:  2.50E+3nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed