Compile Data Set for Download or QSAR
Report error Found 83 Enz. Inhib. hit(s) with all data for entry = 50035841
TargetAlpha-1A adrenergic receptor(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010859(CHEMBL11 | Imipramin | IMIPRAMINE HYDROCHLORIDE | ...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of binding of [3H]imipramine to imipramine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010870(CHEMBL98894 | 1-[1-(3,4-Dichloro-phenyl)-2-dimethy...)
Affinity DataIC50: 37nMAssay Description:Inhibition of binding of [3H]imipramine to imipramine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010867(CHEMBL319142 | 1-[1-(3-Bromo-phenyl)-2-dimethylami...)
Affinity DataIC50: 52nMAssay Description:Inhibition of binding of [3H]imipramine to imipramine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM86748(CAS_386750-22-7 | NSC_6918664 | O-Desmethylvenlafa...)
Affinity DataIC50: 60nMAssay Description:Inhibition of binding of [3H]imipramine to imipramine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010872(CHEMBL99175 | 1-[1-(4-Bromo-phenyl)-2-dimethylamin...)
Affinity DataIC50: 62nMAssay Description:Inhibition of binding of [3H]imipramine to imipramine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTransporter(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010870(CHEMBL98894 | 1-[1-(3,4-Dichloro-phenyl)-2-dimethy...)
Affinity DataIC50: 70nMAssay Description:Inhibition of uptake of tritiated norepinephrine (NE) into rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010870(CHEMBL98894 | 1-[1-(3,4-Dichloro-phenyl)-2-dimethy...)
Affinity DataIC50: 80nMAssay Description:Inhibition of uptake of tritiated serotonin (5-HT) into rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010877(CHEMBL419533 | 1-[2-Dimethylamino-1-(4-trifluorome...)
Affinity DataIC50: 88nMAssay Description:Inhibition of binding of [3H]imipramine to imipramine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM82071(NSC_62923 | WY-45030 | VENLAFAXINE | CAS_93413-69-...)
Affinity DataIC50: 90nMAssay Description:Inhibition of binding of [3H]imipramine to imipramine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM82071(NSC_62923 | WY-45030 | VENLAFAXINE | CAS_93413-69-...)
Affinity DataIC50: 90nMAssay Description:Inhibition of binding of [3H]imipramine to imipramine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010866(CHEMBL98842 | 1-[2-Dimethylamino-1-(3-methoxy-phen...)
Affinity DataIC50: 95nMAssay Description:Inhibition of binding of [3H]imipramine to imipramine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM82071(NSC_62923 | WY-45030 | VENLAFAXINE | CAS_93413-69-...)
Affinity DataIC50: 100nMAssay Description:Inhibition of uptake of tritiated serotonin (5-HT) into rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010874(1-[1-(4-Chloro-phenyl)-2-dimethylamino-ethyl]-cycl...)
Affinity DataIC50: 100nMAssay Description:Inhibition of binding of [3H]imipramine to imipramine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM82071(NSC_62923 | WY-45030 | VENLAFAXINE | CAS_93413-69-...)
Affinity DataIC50: 109nMAssay Description:Inhibition of binding of [3H]imipramine to imipramine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTransporter(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010867(CHEMBL319142 | 1-[1-(3-Bromo-phenyl)-2-dimethylami...)
Affinity DataIC50: 110nMAssay Description:Inhibition of uptake of tritiated norepinephrine (NE) into rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010872(CHEMBL99175 | 1-[1-(4-Bromo-phenyl)-2-dimethylamin...)
Affinity DataIC50: 110nMAssay Description:Inhibition of uptake of tritiated serotonin (5-HT) into rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010859(CHEMBL11 | Imipramin | IMIPRAMINE HYDROCHLORIDE | ...)
Affinity DataIC50: 120nMAssay Description:Inhibition of uptake of tritiated serotonin (5-HT) into rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAlpha-1A adrenergic receptor(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010862(CHEMBL100774 | 1-[2-Dimethylamino-1-(4-methoxy-phe...)
Affinity DataIC50: 126nMAssay Description:Inhibition of binding of [3H]imipramine to imipramine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM35229(Desmethylimipramine | 3-(10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50: 130nMAssay Description:Inhibition of binding of [3H]imipramine to imipramine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010858(CHEMBL101899 | 1-[1-(3-Chloro-phenyl)-2-dimethylam...)
Affinity DataIC50: 130nMAssay Description:Inhibition of binding of [3H]imipramine to imipramine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010878(CHEMBL101819 | 1-[1-(3,4-Dimethoxy-phenyl)-2-dimet...)
Affinity DataIC50: 130nMAssay Description:Inhibition of uptake of tritiated serotonin (5-HT) into rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTransporter(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010873(CHEMBL99503 | 1-[1-(3-Bromo-4-methoxy-phenyl)-2-di...)
Affinity DataIC50: 140nMAssay Description:Inhibition of uptake of tritiated norepinephrine (NE) into rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010879(1-(2-(dimethylamino)-1-(3-methoxyphenyl)ethyl)cycl...)
Affinity DataIC50: 150nMAssay Description:Inhibition of binding of [3H]imipramine to imipramine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTransporter(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM35229(Desmethylimipramine | 3-(10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50: 150nMAssay Description:Inhibition of uptake of tritiated norepinephrine (NE) into rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetTransporter(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010858(CHEMBL101899 | 1-[1-(3-Chloro-phenyl)-2-dimethylam...)
Affinity DataIC50: 160nMAssay Description:Inhibition of uptake of tritiated norepinephrine (NE) into rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM86748(CAS_386750-22-7 | NSC_6918664 | O-Desmethylvenlafa...)
Affinity DataIC50: 180nMAssay Description:Inhibition of uptake of tritiated serotonin (5-HT) into rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010874(1-[1-(4-Chloro-phenyl)-2-dimethylamino-ethyl]-cycl...)
Affinity DataIC50: 180nMAssay Description:Inhibition of uptake of tritiated serotonin (5-HT) into rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010873(CHEMBL99503 | 1-[1-(3-Bromo-4-methoxy-phenyl)-2-di...)
Affinity DataIC50: 190nMAssay Description:Inhibition of binding of [3H]imipramine to imipramine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010879(1-(2-(dimethylamino)-1-(3-methoxyphenyl)ethyl)cycl...)
Affinity DataIC50: 190nMAssay Description:Inhibition of uptake of tritiated serotonin (5-HT) into rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010873(CHEMBL99503 | 1-[1-(3-Bromo-4-methoxy-phenyl)-2-di...)
Affinity DataIC50: 200nMAssay Description:Inhibition of uptake of tritiated serotonin (5-HT) into rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010880(CHEMBL99670 | 1-(2-Dimethylamino-1-p-tolyl-ethyl)-...)
Affinity DataIC50: 205nMAssay Description:Inhibition of binding of [3H]imipramine to imipramine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTransporter(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010872(CHEMBL99175 | 1-[1-(4-Bromo-phenyl)-2-dimethylamin...)
Affinity DataIC50: 210nMAssay Description:Inhibition of uptake of tritiated norepinephrine (NE) into rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM82071(NSC_62923 | WY-45030 | VENLAFAXINE | CAS_93413-69-...)
Affinity DataIC50: 210nMAssay Description:Inhibition of uptake of tritiated serotonin (5-HT) into rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM82071(NSC_62923 | WY-45030 | VENLAFAXINE | CAS_93413-69-...)
Affinity DataIC50: 210nMAssay Description:Inhibition of uptake of tritiated serotonin (5-HT) into rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010867(CHEMBL319142 | 1-[1-(3-Bromo-phenyl)-2-dimethylami...)
Affinity DataIC50: 230nMAssay Description:Inhibition of uptake of tritiated serotonin (5-HT) into rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010864(CHEMBL101056 | 1-[2-Dimethylamino-1-(4-methoxy-phe...)
Affinity DataIC50: 240nMAssay Description:Inhibition of uptake of tritiated serotonin (5-HT) into rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTransporter(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010859(CHEMBL11 | Imipramin | IMIPRAMINE HYDROCHLORIDE | ...)
Affinity DataIC50: 260nMAssay Description:Inhibition of uptake of tritiated norepinephrine (NE) into rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010887(CHEMBL321364 | 1-[1-(2-Bromo-phenyl)-2-dimethylami...)
Affinity DataIC50: 260nMAssay Description:Inhibition of binding of [3H]imipramine to imipramine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010864(CHEMBL101056 | 1-[2-Dimethylamino-1-(4-methoxy-phe...)
Affinity DataIC50: 300nMAssay Description:Inhibition of binding of [3H]imipramine to imipramine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTransporter(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010874(1-[1-(4-Chloro-phenyl)-2-dimethylamino-ethyl]-cycl...)
Affinity DataIC50: 300nMAssay Description:Inhibition of uptake of tritiated norepinephrine (NE) into rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010863(CHEMBL98660 | 1-(2-Dimethylamino-1-phenyl-ethyl)-c...)
Affinity DataIC50: 300nMAssay Description:Inhibition of binding of [3H]imipramine to imipramine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50367952(N-Desmethylvenlafaxine | CHEMBL1628258)
Affinity DataIC50: 300nMAssay Description:Inhibition of binding of [3H]imipramine to imipramine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010858(CHEMBL101899 | 1-[1-(3-Chloro-phenyl)-2-dimethylam...)
Affinity DataIC50: 320nMAssay Description:Inhibition of uptake of tritiated serotonin (5-HT) into rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTransporter(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010884(CHEMBL99653 | 1-[2-Dimethylamino-1-(3-trifluoromet...)
Affinity DataIC50: 360nMAssay Description:Inhibition of uptake of tritiated norepinephrine (NE) into rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010884(CHEMBL99653 | 1-[2-Dimethylamino-1-(3-trifluoromet...)
Affinity DataIC50: 360nMAssay Description:Inhibition of binding of [3H]imipramine to imipramine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010877(CHEMBL419533 | 1-[2-Dimethylamino-1-(4-trifluorome...)
Affinity DataIC50: 400nMAssay Description:Inhibition of uptake of tritiated serotonin (5-HT) into rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010862(CHEMBL100774 | 1-[2-Dimethylamino-1-(4-methoxy-phe...)
Affinity DataIC50: 400nMAssay Description:Inhibition of uptake of tritiated serotonin (5-HT) into rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010876(CHEMBL329923 | 1-[1-(4-Bromo-phenyl)-2-dimethylami...)
Affinity DataIC50: 435nMAssay Description:Inhibition of binding of [3H]imipramine to imipramine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010881(CHEMBL100773 | 1-[2-Dimethylamino-1-(4-trifluorome...)
Affinity DataIC50: 490nMAssay Description:Inhibition of uptake of tritiated serotonin (5-HT) into rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010871(CHEMBL100191 | 1-[2-Dimethylamino-1-(4-trifluorome...)
Affinity DataIC50: 500nMAssay Description:Inhibition of uptake of tritiated serotonin (5-HT) into rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 83 total ) | Next | Last >>
Jump to: