Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50035890
TargetAdenylate cyclase type 5(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004822(CHEMBL24077 | SKF 38393 (+) | SK-383933 | R(+)SKF ...)
Affinity DataEC50:  80nMAssay Description:Effective concentration required to stimulate Adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetAdenylate cyclase type 5(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50010714(CHEMBL68922 | 1-p-Tolyl-2,3,4,5-tetrahydro-1H-benz...)
Affinity DataEC50:  210nMAssay Description:Effective concentration required to stimulate Adenylate cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM82247(SCH 23390,R(+) | CAS_87134-87-0 | CHEMBL2158641 | ...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity to displace [3H]- SCH 23390 against Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Mouse)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM82247(SCH 23390,R(+) | CAS_87134-87-0 | CHEMBL2158641 | ...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity to displace [3H]- SCH 23390 against Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50010707(CHEMBL304535 | 8-Chloro-3-methyl-5-m-tolyl-2,3,4,5...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity to displace [3H]- SCH 23390 against Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50010717(CHEMBL444321 | 8-Chloro-3-methyl-5-o-tolyl-2,3,4,5...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity to displace [3H]- SCH 23390 against Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50010716(CHEMBL303012 | 8-Chloro-3-methyl-5-p-tolyl-2,3,4,5...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity to displace [3H]- SCH 23390 against Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004823(CHEMBL298406 | Ecopipam | SCH 39166 | (6aS,13bR)-1...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity to displace [3H]-SCH- 23390 against Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004822(CHEMBL24077 | SKF 38393 (+) | SK-383933 | R(+)SKF ...)
Affinity DataKi:  5.10nMAssay Description:Binding affinity against Dopamine receptor D1 in rat radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50010709(CHEMBL71600 | NNC-112,(-) | NNC-112 | 5-Benzofuran...)
Affinity DataKi:  6nMAssay Description:Binding affinity to displace [3H]-SCH- 23390 against Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004820(CHEMBL307790 | 3-Chloro-7-methyl-5,6,7,7a,8,12b-he...)
Affinity DataKi:  7nMAssay Description:Binding affinity to displace [3H]- SCH 23390 against Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50010708(CHEMBL25305 | 6-Phenyl-2,6,7,8,9,9a-hexahydro-1H-8...)
Affinity DataKi:  24nMAssay Description:Binding affinity against Dopamine receptor D1 in rat radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataKi:  192nMAssay Description:Binding affinity to displace [3H]- SCH 23390 against Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(1A) dopamine receptor(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50010715(CHEMBL58422 | (6aS,13bS)11-Chloro-7-methyl-5,6a,7,...)
Affinity DataKi:  513nMAssay Description:Binding affinity to displace [3H]-SCH- 23390 against Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50010711(cis-(-) 11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydr...)
Affinity DataKi:  531nMAssay Description:Binding affinity to displace [3H]-SCH- 23390 against Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50010712(CHEMBL294012 | (6aR,13bR)11-Chloro-7-methyl-5,6a,7...)
Affinity DataKi:  898nMAssay Description:Binding affinity to displace [3H]-SCH- 23390 against Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50010710(CHEMBL282710 | 6-Phenyl-2,6,7,8,9,9a-hexahydro-1H-...)
Affinity DataKi:  1.22E+3nMAssay Description:Binding affinity against Dopamine receptor D1 in rat radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed