Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50030823
TargetSonic hedgehog protein(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50302111(N-(4-chloro-3-(1-methyl-1H-benzo[d]imidazol-2-yl)p...)
Affinity DataIC50: 9nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50302139(N-(3-(1H-benzo[d]imidazol-2-yl)-4-chlorophenyl)-2-...)
Affinity DataIC50: 12nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50249522(2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(me...)
Affinity DataIC50: 13nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50302138(N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulfo...)
Affinity DataIC50: 40nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50302123(N-(4-chloro-3-(pyridin-2-yl)phenyl)-2-methyl-6-(tr...)
Affinity DataIC50: 42nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50302128(N-(4-chloro-3-(quinoxalin-2-yl)phenyl)-2-methyl-6-...)
Affinity DataIC50: 52nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50302113(N-(3-(benzo[d]thiazol-2-yl)-4-chlorophenyl)-2-meth...)
Affinity DataIC50: 70nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50302115(N-(4-chloro-3-(2H-indazol-2-yl)phenyl)-2-methyl-6-...)
Affinity DataIC50: 80nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50302134(2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)benzam...)
Affinity DataIC50: 110nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50302137(N-(4-chloro-3-(pyridin-2-yl)phenyl)-3-(methylsulfo...)
Affinity DataIC50: 120nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50302129(N-(4-chloro-3-(pyridin-2-yl)phenyl)-2,6-dimethylni...)
Affinity DataIC50: 130nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50302118(N-(4-chloro-3-(phenylcarbamoyl)phenyl)-2-methyl-6-...)
Affinity DataIC50: 140nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50302112(N-(4-chloro-3-(1-methyl-4,5,6,7-tetrahydro-1H-benz...)
Affinity DataIC50: 150nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50302114(N-(4-chloro-3-(pyrazolo[1,5-a]pyridin-2-yl)phenyl)...)
Affinity DataIC50: 170nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50302117(N-(4-chloro-3-(imidazo[2,1-b]thiazol-6-yl)phenyl)-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50302119(N-(4-chloro-3-(5-methyl-1H-imidazol-2-yl)phenyl)-2...)
Affinity DataIC50: 256nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50302120(N-(4-chloro-3-(1H-pyrazol-1-yl)phenyl)-2-methyl-6-...)
Affinity DataIC50: 450nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50302110(N-(4-chloro-3-(1H-indol-2-yl)phenyl)-2-methyl-6-(t...)
Affinity DataIC50: 500nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50302122(N-(4-chloro-3-(1-methyl-1H-pyrazol-3-yl)phenyl)-2-...)
Affinity DataIC50: 550nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50302131(N-(4-chloro-3-(pyridin-2-yl)phenyl)nicotinamide | ...)
Affinity DataIC50: 600nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50302132(N-(4-chloro-3-(pyridin-2-yl)phenyl)isonicotinamide...)
Affinity DataIC50: 700nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50302133(N-(4-chloro-3-(pyridin-2-yl)phenyl)benzamide | CHE...)
Affinity DataIC50: 800nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50302135(3-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)benzam...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50302136(4-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)benzam...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50302127(N-(4-chloro-3-(pyrazin-2-yl)phenyl)-2-methyl-6-(tr...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50302125(N-(4-chloro-3-(pyridin-4-yl)phenyl)-2-methyl-6-(tr...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50302111(N-(4-chloro-3-(1-methyl-1H-benzo[d]imidazol-2-yl)p...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50302130(N-(4-chloro-3-(pyridin-2-yl)phenyl)picolinamide | ...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50302116(N-(4-chloro-3-(indolizin-2-yl)phenyl)-2-methyl-6-(...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50302126(N-(4-chloro-3-(pyrimidin-2-yl)phenyl)-2-methyl-6-(...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50302121(N-(4-chloro-3-(1H-pyrazol-3-yl)phenyl)-2-methyl-6-...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50302124(N-(4-chloro-3-(pyridin-3-yl)phenyl)-2-methyl-6-(tr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SHH in mouse C3H10T1/2 cells by Gli-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed