Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50030727
TargetCell division control protein 42 homolog(Human)
Exonhit Therapeutics

Curated by ChEMBL
LigandPNGBDBM50300554(((2S,3R,4S,5S)-5-(2-amino-6-oxo-1H-purin-9(6H)-yl)...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetRas-related C3 botulinum toxin substrate 1(Human)
Exonhit Therapeutics

Curated by ChEMBL
LigandPNGBDBM50300554(((2S,3R,4S,5S)-5-(2-amino-6-oxo-1H-purin-9(6H)-yl)...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of Rac1 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCell division control protein 42 homolog(Human)
Exonhit Therapeutics

Curated by ChEMBL
LigandPNGBDBM50300547(2,3,9,10-Tetrahydroxy-5,6-dihydro-isoquino[3,2-a]i...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetRas-related C3 botulinum toxin substrate 1(Human)
Exonhit Therapeutics

Curated by ChEMBL
LigandPNGBDBM50300547(2,3,9,10-Tetrahydroxy-5,6-dihydro-isoquino[3,2-a]i...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of Rac1 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetRas-related C3 botulinum toxin substrate 1(Human)
Exonhit Therapeutics

Curated by ChEMBL
LigandPNGBDBM50300551(2,3,7,8-Tetrahydroxy-5-methyl-benzo[c]phenanthridi...)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of Rac1 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCell division control protein 42 homolog(Human)
Exonhit Therapeutics

Curated by ChEMBL
LigandPNGBDBM50300551(2,3,7,8-Tetrahydroxy-5-methyl-benzo[c]phenanthridi...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCell division control protein 42 homolog(Human)
Exonhit Therapeutics

Curated by ChEMBL
LigandPNGBDBM50300548(3,4,10,11-Tetrahydroxy-8-methyl-isoquino[3,2-a]iso...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCell division control protein 42 homolog(Human)
Exonhit Therapeutics

Curated by ChEMBL
LigandPNGBDBM25525(CHEMBL490129 | 24-methyl-5,7,18,20-tetraoxa-24-aza...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetRas-related C3 botulinum toxin substrate 1(Human)
Exonhit Therapeutics

Curated by ChEMBL
LigandPNGBDBM50300545(tetrahydroxycanadine hydrochloride | CHEMBL573174)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of Rac1 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetRas-related C3 botulinum toxin substrate 1(Human)
Exonhit Therapeutics

Curated by ChEMBL
LigandPNGBDBM50300548(3,4,10,11-Tetrahydroxy-8-methyl-isoquino[3,2-a]iso...)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of Rac1 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetRas-related C3 botulinum toxin substrate 1(Human)
Exonhit Therapeutics

Curated by ChEMBL
LigandPNGBDBM50300552(2,3-Dihydroxy-7,8-dimethoxy-5-methyl-benzo[c]phena...)
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of Rac1 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetRas-related C3 botulinum toxin substrate 1(Human)
Exonhit Therapeutics

Curated by ChEMBL
LigandPNGBDBM50300546(6,7-Dimethoxy-1-methyl-3-naphthalen-2-yl-isoquinol...)
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of Rac1 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetRas-related C3 botulinum toxin substrate 1(Human)
Exonhit Therapeutics

Curated by ChEMBL
LigandPNGBDBM25525(CHEMBL490129 | 24-methyl-5,7,18,20-tetraoxa-24-aza...)
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of Rac1 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetRas-related C3 botulinum toxin substrate 1(Human)
Exonhit Therapeutics

Curated by ChEMBL
LigandPNGBDBM50300549(2,3-Dihydroxy-9,10-dimethoxy-5,6-dihydro-isoquino[...)
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of Rac1 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCell division control protein 42 homolog(Human)
Exonhit Therapeutics

Curated by ChEMBL
LigandPNGBDBM50300552(2,3-Dihydroxy-7,8-dimethoxy-5-methyl-benzo[c]phena...)
Affinity DataIC50: 7.30E+4nMAssay Description:Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCell division control protein 42 homolog(Human)
Exonhit Therapeutics

Curated by ChEMBL
LigandPNGBDBM25524(CHEMBL13045 | 17,18-dimethoxy-21-methyl-5,7-dioxa-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCell division control protein 42 homolog(Human)
Exonhit Therapeutics

Curated by ChEMBL
LigandPNGBDBM50300549(2,3-Dihydroxy-9,10-dimethoxy-5,6-dihydro-isoquino[...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCell division control protein 42 homolog(Human)
Exonhit Therapeutics

Curated by ChEMBL
LigandPNGBDBM50300550(3-(3,4-Dihydroxy-phenyl)-6,7-dimethoxy-1-methyl-is...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetRas-related C3 botulinum toxin substrate 1(Human)
Exonhit Therapeutics

Curated by ChEMBL
LigandPNGBDBM25524(CHEMBL13045 | 17,18-dimethoxy-21-methyl-5,7-dioxa-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Rac1 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCell division control protein 42 homolog(Human)
Exonhit Therapeutics

Curated by ChEMBL
LigandPNGBDBM50300545(tetrahydroxycanadine hydrochloride | CHEMBL573174)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCell division control protein 42 homolog(Human)
Exonhit Therapeutics

Curated by ChEMBL
LigandPNGBDBM50300546(6,7-Dimethoxy-1-methyl-3-naphthalen-2-yl-isoquinol...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetRas-related C3 botulinum toxin substrate 1(Human)
Exonhit Therapeutics

Curated by ChEMBL
LigandPNGBDBM50300550(3-(3,4-Dihydroxy-phenyl)-6,7-dimethoxy-1-methyl-is...)
Affinity DataIC50: 1.04E+5nMAssay Description:Inhibition of Rac1 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed