Compile Data Set for Download or QSAR
Report error Found 66 Enz. Inhib. hit(s) with all data for entry = 50030725
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM35229(Desmethylimipramine | 3-(10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300525((1S,2R)-1-(3-fluorophenyl)-1-(3-methyl-1H-indol-1-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300513((1S,2R)-1-(7-fluoro-1H-indol-1-yl)-1-(3-fluorophen...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM30130(Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300524((1S,2R)-1-(3-ethyl-1H-indol-1-yl)-1-(3-fluoropheny...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300533((1S,2R)-1-(3-fluorophenyl)-1-(1H-indol-1-yl)-3-(me...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300527((1S,2R)-1-(3-bromophenyl)-1-(1H-indol-1-yl)-3-(met...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300507((R)-3-(3-fluorophenyl)-3-(1H-indol-1-yl)-N-methylp...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300519((1S,2R)-1-(3-fluorophenyl)-1-(4-methyl-1H-indol-1-...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300536((1S,2R)-1-(3-chlorophenyl)-1-(1H-indol-1-yl)-3-(me...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300516((1S,2R)-1-(4-fluoro-1H-indol-1-yl)-1-(3-fluorophen...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300517((1S,2R)-1-(3-fluorophenyl)-1-(7-methyl-1H-indol-1-...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300514((1S,2R)-1-(6-fluoro-1H-indol-1-yl)-1-(3-fluorophen...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300509((1S,2R)-1-(7-bromo-1H-indol-1-yl)-1-(3-fluoropheny...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300520((1S,2R)-1-(7-chloro-1H-indol-1-yl)-1-(3-fluorophen...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300518((1S,2R)-1-(3-fluorophenyl)-1-(5-methyl-1H-indol-1-...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300515((1S,2R)-1-(5-fluoro-1H-indol-1-yl)-1-(3-fluorophen...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50297365((1S,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-phenyl...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300508((R)-3-(1H-indol-1-yl)-N-methyl-3-phenylpropan-1-am...)
Affinity DataIC50: 34nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300518((1S,2R)-1-(3-fluorophenyl)-1-(5-methyl-1H-indol-1-...)
Affinity DataIC50: 48nMAssay Description:Inhibition of human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300520((1S,2R)-1-(7-chloro-1H-indol-1-yl)-1-(3-fluorophen...)
Affinity DataIC50: 48nMAssay Description:Inhibition of human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300530((1S,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-m-toly...)
Affinity DataIC50: 49nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300512((1S,2R)-1-(4-bromo-1H-indol-1-yl)-1-(3-fluoropheny...)
Affinity DataIC50: 52nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300511((1S,2R)-1-(5-bromo-1H-indol-1-yl)-1-(3-fluoropheny...)
Affinity DataIC50: 52nMAssay Description:Inhibition of human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300526((1S,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-(3-(tr...)
Affinity DataIC50: 54nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300511((1S,2R)-1-(5-bromo-1H-indol-1-yl)-1-(3-fluoropheny...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300522((1S,2R)-1-(5-chloro-1H-indol-1-yl)-1-(3-fluorophen...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300523((1S,2R)-1-(4-chloro-1H-indol-1-yl)-1-(3-fluorophen...)
Affinity DataIC50: 64nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300515((1S,2R)-1-(5-fluoro-1H-indol-1-yl)-1-(3-fluorophen...)
Affinity DataIC50: 78nMAssay Description:Inhibition of human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300522((1S,2R)-1-(5-chloro-1H-indol-1-yl)-1-(3-fluorophen...)
Affinity DataIC50: 79nMAssay Description:Inhibition of human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300532((1S,2R)-1-(4-fluorophenyl)-1-(1H-indol-1-yl)-3-(me...)
Affinity DataIC50: 84nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300507((R)-3-(3-fluorophenyl)-3-(1H-indol-1-yl)-N-methylp...)
Affinity DataIC50: 91nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300521((1S,2R)-1-(6-chloro-1H-indol-1-yl)-1-(3-fluorophen...)
Affinity DataIC50: 92nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300534((1S,2R)-1-(2-fluorophenyl)-1-(1H-indol-1-yl)-3-(me...)
Affinity DataIC50: 92nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300528((1S,2R)-1-(1H-indol-1-yl)-1-(3-methoxyphenyl)-3-(m...)
Affinity DataIC50: 111nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300509((1S,2R)-1-(7-bromo-1H-indol-1-yl)-1-(3-fluoropheny...)
Affinity DataIC50: 113nMAssay Description:Inhibition of human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300529((1S,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-p-toly...)
Affinity DataIC50: 117nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300510((1S,2R)-1-(6-bromo-1H-indol-1-yl)-1-(3-fluoropheny...)
Affinity DataIC50: 124nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300513((1S,2R)-1-(7-fluoro-1H-indol-1-yl)-1-(3-fluorophen...)
Affinity DataIC50: 175nMAssay Description:Inhibition of human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300512((1S,2R)-1-(4-bromo-1H-indol-1-yl)-1-(3-fluoropheny...)
Affinity DataIC50: 207nMAssay Description:Inhibition of human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300523((1S,2R)-1-(4-chloro-1H-indol-1-yl)-1-(3-fluorophen...)
Affinity DataIC50: 221nMAssay Description:Inhibition of human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300519((1S,2R)-1-(3-fluorophenyl)-1-(4-methyl-1H-indol-1-...)
Affinity DataIC50: 228nMAssay Description:Inhibition of human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300531((1S,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-o-toly...)
Affinity DataIC50: 232nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300531((1S,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-o-toly...)
Affinity DataIC50: 266nMAssay Description:Inhibition of human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300537((1S,2R)-1-(2-chlorophenyl)-1-(1H-indol-1-yl)-3-(me...)
Affinity DataIC50: 304nMAssay Description:Inhibition of human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300525((1S,2R)-1-(3-fluorophenyl)-1-(3-methyl-1H-indol-1-...)
Affinity DataIC50: 343nMAssay Description:Inhibition of human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50297365((1S,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-phenyl...)
Affinity DataIC50: 358nMAssay Description:Inhibition of human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300530((1S,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-m-toly...)
Affinity DataIC50: 377nMAssay Description:Inhibition of human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300529((1S,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-p-toly...)
Affinity DataIC50: 398nMAssay Description:Inhibition of human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300516((1S,2R)-1-(4-fluoro-1H-indol-1-yl)-1-(3-fluorophen...)
Affinity DataIC50: 417nMAssay Description:Inhibition of human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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