Compile Data Set for Download or QSAR
Report error Found 68 Enz. Inhib. hit(s) with all data for entry = 50030810
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301856(7-(trifluoromethyl)-N-(4-(trifluoromethyl)phenyl)b...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301869(7-(2-(trifluoromethyl)phenyl)-N-(4-(trifluoromethy...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301859(6-(2-(trifluoromethyl)phenyl)-N-(4-(trifluoromethy...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301871(7-(1H-indol-5-yl)-N-(4-(trifluoromethyl)phenyl)ben...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301870(7-(3-(trifluoromethyl)phenyl)-N-(4-(trifluoromethy...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301857(6-(trifluoromethyl)-N-(4-(trifluoromethyl)phenyl)b...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301867(6-(pyridin-4-yl)-N-(4-(trifluoromethyl)phenyl)benz...)
Affinity DataIC50: 19nMAssay Description:Inhibition of rat sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301860(6-(isoquinolin-5-yl)-N-(4-(trifluoromethyl)phenyl)...)
Affinity DataIC50: 19nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301872(7-(trifluoromethyl)-N-(4-(trifluoromethyl)phenyl)i...)
Affinity DataIC50: 19nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301866(6-(pyridin-3-yl)-N-(4-(trifluoromethyl)phenyl)benz...)
Affinity DataIC50: 20nMAssay Description:Inhibition of rat sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301866(6-(pyridin-3-yl)-N-(4-(trifluoromethyl)phenyl)benz...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301873(N-(4-(trifluoromethyl)phenyl)benzo[d]isoxazol-3-am...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301893(N-(4-(trifluoromethyl)phenyl)isoxazolo[5,4-b]pyrid...)
Affinity DataIC50: 27nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301860(6-(isoquinolin-5-yl)-N-(4-(trifluoromethyl)phenyl)...)
Affinity DataIC50: 30nMAssay Description:Inhibition of rat sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301894(N-(4-(trifluoromethyl)phenyl)isoxazolo[5,4-c]pyrid...)
Affinity DataIC50: 31nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301858(5-(trifluoromethyl)-N-(4-(trifluoromethyl)phenyl)b...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301871(7-(1H-indol-5-yl)-N-(4-(trifluoromethyl)phenyl)ben...)
Affinity DataIC50: 41nMAssay Description:Inhibition of rat sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301865(6-(2-fluorophenyl)-N-(4-(trifluoromethyl)phenyl)be...)
Affinity DataIC50: 55nMAssay Description:Inhibition of rat sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301867(6-(pyridin-4-yl)-N-(4-(trifluoromethyl)phenyl)benz...)
Affinity DataIC50: 58nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301874(N-(4-(trifluoromethoxy)phenyl)benzo[d]isoxazol-3-a...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301868(6-(3-methylpyridin-2-yl)-N-(4-(trifluoromethyl)phe...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301859(6-(2-(trifluoromethyl)phenyl)-N-(4-(trifluoromethy...)
Affinity DataIC50: 70nMAssay Description:Inhibition of rat sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301861(6-(1H-indol-5-yl)-N-(4-(trifluoromethyl)phenyl)ben...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301863(7-(trifluoromethyl)-N-(6-(trifluoromethyl)pyridin-...)
Affinity DataIC50: 74nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301873(N-(4-(trifluoromethyl)phenyl)benzo[d]isoxazol-3-am...)
Affinity DataIC50: 76nMAssay Description:Inhibition of rat sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301861(6-(1H-indol-5-yl)-N-(4-(trifluoromethyl)phenyl)ben...)
Affinity DataIC50: 77nMAssay Description:Inhibition of rat sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301869(7-(2-(trifluoromethyl)phenyl)-N-(4-(trifluoromethy...)
Affinity DataIC50: 79nMAssay Description:Inhibition of rat sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301865(6-(2-fluorophenyl)-N-(4-(trifluoromethyl)phenyl)be...)
Affinity DataIC50: 91nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301856(7-(trifluoromethyl)-N-(4-(trifluoromethyl)phenyl)b...)
Affinity DataIC50: 127nMAssay Description:Inhibition of rat sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301870(7-(3-(trifluoromethyl)phenyl)-N-(4-(trifluoromethy...)
Affinity DataIC50: 130nMAssay Description:Inhibition of rat sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301875(N-(3-(trifluoromethoxy)phenyl)benzo[d]isoxazol-3-a...)
Affinity DataIC50: 160nMAssay Description:Inhibition of rat sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301875(N-(3-(trifluoromethoxy)phenyl)benzo[d]isoxazol-3-a...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301876(N-(biphenyl-4-yl)benzo[d]isoxazol-3-amine | CHEMBL...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301874(N-(4-(trifluoromethoxy)phenyl)benzo[d]isoxazol-3-a...)
Affinity DataIC50: 170nMAssay Description:Inhibition of rat sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301868(6-(3-methylpyridin-2-yl)-N-(4-(trifluoromethyl)phe...)
Affinity DataIC50: 290nMAssay Description:Inhibition of rat sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301872(7-(trifluoromethyl)-N-(4-(trifluoromethyl)phenyl)i...)
Affinity DataIC50: 300nMAssay Description:Inhibition of rat sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301895(N-(4-(trifluoromethyl)phenyl)isoxazolo[4,5-c]pyrid...)
Affinity DataIC50: 340nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301864(6-(3-(trifluoromethyl)phenyl)-N-(4-(trifluoromethy...)
Affinity DataIC50: 470nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301864(6-(3-(trifluoromethyl)phenyl)-N-(4-(trifluoromethy...)
Affinity DataIC50: 570nMAssay Description:Inhibition of rat sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301876(N-(biphenyl-4-yl)benzo[d]isoxazol-3-amine | CHEMBL...)
Affinity DataIC50: 740nMAssay Description:Inhibition of rat sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301855(N-(naphthalen-1-yl)benzo[d]isoxazol-3-amine | CHEM...)
Affinity DataIC50: 840nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301897(N-(2-(trifluoromethyl)phenyl)benzo[d]isoxazol-3-am...)
Affinity DataIC50: 960nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301853(N-(biphenyl-3-yl)benzo[d]isoxazol-3-amine | CHEMBL...)
Affinity DataIC50: 960nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301896(N-(4-(trifluoromethyl)phenyl)isoxazolo[4,5-b]pyrid...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301856(7-(trifluoromethyl)-N-(4-(trifluoromethyl)phenyl)b...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human sEH assessed as DHET production in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301854(N-(naphthalen-2-yl)benzo[d]isoxazol-3-amine | CHEM...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301889(N-(4-(trifluoromethyl)benzyl)benzo[d]isoxazol-3-am...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301858(5-(trifluoromethyl)-N-(4-(trifluoromethyl)phenyl)b...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of rat sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301886(N-phenyl-5-(trifluoromethyl)-1,3,4-oxadiazol-2-ami...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301887(N-(4-(trifluoromethyl)phenyl)benzo[d]isothiazol-3-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human sEHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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