Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50038975
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50258478(2-(3,4-difluorophenyl)-N-(3-(6-fluoro-1H-spiro[fur...)
Affinity DataIC50: 0.0900nMAssay Description:Displacement of [125I]MCH from human MCH1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301705((Z)-(3,4-difluorophenyl)(4-((6-fluoro-1H-spiro[fur...)
Affinity DataIC50: 0.120nMAssay Description:Displacement of [125I]MCH from human MCH1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301704((Z)-(3,4-difluorophenyl)(4-((6-fluoro-1H-spiro[fur...)
Affinity DataIC50: 0.220nMAssay Description:Displacement of [125I]MCH from human MCH1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301702(CHEMBL582978 | CHEMBL565614 | (Z)-(3,4-difluorophe...)
Affinity DataIC50: 0.260nMAssay Description:Displacement of [125I]MCH from human MCH1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301706((Z)-(3,4-difluorophenyl)(5-((6-fluoro-1H-spiro[fur...)
Affinity DataIC50: 0.350nMAssay Description:Displacement of [125I]MCH from human MCH1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50295690(CHEMBL538424 | (+/-)-2-(3,4-difluorophenyl)-N-ethy...)
Affinity DataIC50: 0.360nMAssay Description:Displacement of [125I]MCH from human MCH1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301702(CHEMBL582978 | CHEMBL565614 | (Z)-(3,4-difluorophe...)
Affinity DataIC50: 1.20nMAssay Description:Displacement of [125I]MCH from human MCH1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301698(3,4-difluoro-N-(4-((6-fluoro-1H-spiro[furo[3,4-c]p...)
Affinity DataIC50: 1.30nMAssay Description:Displacement of [125I]MCH from human MCH1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301701((3,4-difluorophenyl)(4-((6-fluoro-1H-spiro[furo[3,...)
Affinity DataIC50: 1.40nMAssay Description:Displacement of [125I]MCH from human MCH1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Rat)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50219047(N-(3-{1-[4-(3,4-difluorophenoxy)benzyl]-4-piperidi...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of rat MCH1R receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301700(rac-1-(3,4-difluorophenyl)-1-(4-((6-fluoro-1H-spir...)
Affinity DataIC50: 2.60nMAssay Description:Displacement of [125I]MCH from human MCH1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301696(1'-(4-(3,4-difluorophenoxy)benzyl)-6-fluoro-1H-spi...)
Affinity DataIC50: 3.5nMAssay Description:Displacement of [125I]MCH from human MCH1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301697(3,4-difluoro-N-(4-((6-fluoro-1H-spiro[furo[3,4-c]p...)
Affinity DataIC50: 4.60nMAssay Description:Displacement of [125I]MCH from human MCH1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301699(rac-(3,4-difluorophenyl)(4-((6-fluoro-1H-spiro[fur...)
Affinity DataIC50: 6.30nMAssay Description:Displacement of [125I]MCH from human MCH1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301708((Z)-1'-((6-((3,4-difluorophenyl)(ethoxyimino)methy...)
Affinity DataIC50: 6.80nMAssay Description:Displacement of [125I]MCH from human MCH1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Rat)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301708((Z)-1'-((6-((3,4-difluorophenyl)(ethoxyimino)methy...)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of rat MCH1R receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanin-concentrating hormone receptor 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301708((Z)-1'-((6-((3,4-difluorophenyl)(ethoxyimino)methy...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human MCH2RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Mouse)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301708((Z)-1'-((6-((3,4-difluorophenyl)(ethoxyimino)methy...)
Affinity DataIC50: 12nMAssay Description:Inhibition of mouse MCH1R receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301701((3,4-difluorophenyl)(4-((6-fluoro-1H-spiro[furo[3,...)
Affinity DataIC50: 17nMAssay Description:Displacement of [35S]MK-499 from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301697(3,4-difluoro-N-(4-((6-fluoro-1H-spiro[furo[3,4-c]p...)
Affinity DataIC50: 23nMAssay Description:Displacement of [35S]MK-499 from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301696(1'-(4-(3,4-difluorophenoxy)benzyl)-6-fluoro-1H-spi...)
Affinity DataIC50: 24nMAssay Description:Displacement of [35S]MK-499 from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301708((Z)-1'-((6-((3,4-difluorophenyl)(ethoxyimino)methy...)
Affinity DataIC50: 25nMAssay Description:Antagonist activity against human MCH1R receptor expressed in CHO cells assessed as inhibition of MCH-induced calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301698(3,4-difluoro-N-(4-((6-fluoro-1H-spiro[furo[3,4-c]p...)
Affinity DataIC50: 25nMAssay Description:Displacement of [35S]MK-499 from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301707((Z)-1'-((6-((3,4-difluorophenyl)(ethoxyimino)methy...)
Affinity DataIC50: 45nMAssay Description:Displacement of [125I]MCH from human MCH1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301705((Z)-(3,4-difluorophenyl)(4-((6-fluoro-1H-spiro[fur...)
Affinity DataIC50: 140nMAssay Description:Displacement of [35S]MK-499 from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301704((Z)-(3,4-difluorophenyl)(4-((6-fluoro-1H-spiro[fur...)
Affinity DataIC50: 250nMAssay Description:Displacement of [35S]MK-499 from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301702(CHEMBL582978 | CHEMBL565614 | (Z)-(3,4-difluorophe...)
Affinity DataIC50: 280nMAssay Description:Displacement of [35S]MK-499 from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301702(CHEMBL582978 | CHEMBL565614 | (Z)-(3,4-difluorophe...)
Affinity DataIC50: 310nMAssay Description:Displacement of [35S]MK-499 from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301699(rac-(3,4-difluorophenyl)(4-((6-fluoro-1H-spiro[fur...)
Affinity DataIC50: 520nMAssay Description:Displacement of [35S]MK-499 from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301700(rac-1-(3,4-difluorophenyl)-1-(4-((6-fluoro-1H-spir...)
Affinity DataIC50: 530nMAssay Description:Displacement of [35S]MK-499 from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301706((Z)-(3,4-difluorophenyl)(5-((6-fluoro-1H-spiro[fur...)
Affinity DataIC50: 1.79E+3nMAssay Description:Displacement of [35S]MK-499 from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301708((Z)-1'-((6-((3,4-difluorophenyl)(ethoxyimino)methy...)
Affinity DataIC50: 3.67E+3nMAssay Description:Displacement of [35S]MK-499 from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301707((Z)-1'-((6-((3,4-difluorophenyl)(ethoxyimino)methy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [35S]MK-499 from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed