Compile Data Set for Download or QSAR
Report error Found 93 Enz. Inhib. hit(s) with all data for entry = 50030793
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301509(1-(3-(4-bromo-1-methyl-1H-pyrazol-5-yl)-4-(2-(pyrr...)
Affinity DataIC50: 1.90nMAssay Description:Agonist activity at 5HT2A receptor expressed in HEK cells assessed as inhibition of serotonin-induced inositol phosphate accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301481(1-(4-chlorophenyl)-3-(4-(2-(4-methoxypiperidin-1-y...)
Affinity DataKi:  0.120nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301506(1-(3-(4-chloro-1-methyl-1H-pyrazol-5-yl)-4-(2-morp...)
Affinity DataKi:  0.150nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301511(1-(4-chlorophenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)...)
Affinity DataKi:  0.150nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301502(1-(3-(4-bromo-1-methyl-1H-pyrazol-5-yl)-4-(2-(pyrr...)
Affinity DataKi:  0.180nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301517(1-(4-chlorophenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)...)
Affinity DataKi:  0.190nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301476(1-(4-(2-(1,4-oxazepan-4-yl)ethoxy)-3-(1-methyl-1H-...)
Affinity DataKi:  0.220nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301495(1-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-(piperidin-1-...)
Affinity DataKi:  0.25nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301510(1-(3-(4-chloro-1-methyl-1H-pyrazol-5-yl)-4-(2-(pyr...)
Affinity DataKi:  0.260nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301509(1-(3-(4-bromo-1-methyl-1H-pyrazol-5-yl)-4-(2-(pyrr...)
Affinity DataKi:  0.280nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301503(1-(3-(4-chloro-1-methyl-1H-pyrazol-5-yl)-4-(2-(pyr...)
Affinity DataKi:  0.280nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301507(1-(3-(4-chloro-1-methyl-1H-pyrazol-5-yl)-4-(2-morp...)
Affinity DataKi:  0.310nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301488(1-(3-chlorophenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)...)
Affinity DataKi:  0.330nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301496(1-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-(piperidin-1-...)
Affinity DataKi:  0.340nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301504(1-(3-(4-bromo-1-methyl-1H-pyrazol-5-yl)-4-(2-(pyrr...)
Affinity DataKi:  0.360nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301514(1-(4-chlorophenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)...)
Affinity DataKi:  0.410nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301480(1-(4-chlorophenyl)-3-(4-(2-(4-hydroxypiperidin-1-y...)
Affinity DataKi:  0.420nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301513(1-(3-(4-chloro-1-methyl-1H-pyrazol-5-yl)-4-(2-(pip...)
Affinity DataKi:  0.430nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301518(1-(4-chlorophenyl)-3-(4-(2-(diethylamino)ethoxy)-3...)
Affinity DataKi:  0.430nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301494(1-(4-methoxyphenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl...)
Affinity DataKi:  0.540nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301519(1-(4-chlorophenyl)-3-(4-(3-(diethylamino)propoxy)-...)
Affinity DataKi:  0.550nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301475(1-(4-chlorophenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)...)
Affinity DataKi:  0.580nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301516(1-(3-(4-chloro-1-methyl-1H-pyrazol-5-yl)-4-(2-morp...)
Affinity DataKi:  0.610nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301515(1-(3-(4-bromo-1-methyl-1H-pyrazol-5-yl)-4-(2-morph...)
Affinity DataKi:  0.630nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301512(1-(3-(4-bromo-1-methyl-1H-pyrazol-5-yl)-4-(2-(pipe...)
Affinity DataKi:  0.660nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301482(1-(4-(2-(azetidin-1-yl)ethoxy)-3-(1-methyl-1H-pyra...)
Affinity DataKi:  0.690nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301508(1-(3-fluorophenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)...)
Affinity DataKi:  0.820nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301491(1-(4-fluorophenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)...)
Affinity DataKi:  0.840nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301484(1-(4-chlorophenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)...)
Affinity DataKi:  0.840nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301501(1-(4-(2-(diethylamino)ethoxy)-3-(1-methyl-1H-pyraz...)
Affinity DataKi:  0.860nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301500(1-(3,5-difluorophenyl)-3-(3-(1-methyl-1H-pyrazol-5...)
Affinity DataKi:  0.910nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301479(1-(4-(2-(4-acetylpiperazin-1-yl)ethoxy)-3-(1-methy...)
Affinity DataKi:  0.960nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301490(1-(3-fluorophenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)...)
Affinity DataKi:  0.990nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301483(1-(4-chlorophenyl)-3-(4-(2-(3-methoxyazetidin-1-yl...)
Affinity DataKi:  0.990nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301492(1-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-(piperidin-1-...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301486(1-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-(piperidin-1-...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301509(1-(3-(4-bromo-1-methyl-1H-pyrazol-5-yl)-4-(2-(pyrr...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity to 5HT2C receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301505(1-(3-(4-bromo-1-methyl-1H-pyrazol-5-yl)-4-(2-(pyrr...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301478(1-(4-chlorophenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301499(1-(2-fluoro-5-methylphenyl)-3-(3-(1-methyl-1H-pyra...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301487(1-(2-chlorophenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301495(1-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-(piperidin-1-...)
Affinity DataKi:  2.90nMAssay Description:Binding affinity to 5HT2C receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301510(1-(3-(4-chloro-1-methyl-1H-pyrazol-5-yl)-4-(2-(pyr...)
Affinity DataKi:  3nMAssay Description:Binding affinity to 5HT2C receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301498(1-(2,4-difluorophenyl)-3-(3-(1-methyl-1H-pyrazol-5...)
Affinity DataKi:  3.20nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301493(1-(3-methoxyphenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl...)
Affinity DataKi:  3.30nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301474(1-(4-chlorophenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)...)
Affinity DataKi:  4nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301482(1-(4-(2-(azetidin-1-yl)ethoxy)-3-(1-methyl-1H-pyra...)
Affinity DataKi:  5.40nMAssay Description:Binding affinity to 5HT2C receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301489(1-(2-fluorophenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)...)
Affinity DataKi:  6.10nMAssay Description:Displacement of [125I]DOI from 5HT2A receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301518(1-(4-chlorophenyl)-3-(4-(2-(diethylamino)ethoxy)-3...)
Affinity DataKi:  8.80nMAssay Description:Binding affinity to 5HT2C receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50301511(1-(4-chlorophenyl)-3-(3-(1-methyl-1H-pyrazol-5-yl)...)
Affinity DataKi:  9nMAssay Description:Binding affinity to 5HT2C receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 93 total ) | Next | Last >>
Jump to: