Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50030788
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM22874(CHEMBL914 | Allegra | 2-(4-{1-hydroxy-4-[4-(hydrox...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human ERG in L929 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50017376(1-(4-tert-butylphenyl)-4-(4-(hydroxydiphenylmethyl...)
Affinity DataIC50: 312nMAssay Description:Inhibition of human ERG in L929 cells at 10 uM by whole cell patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50017376(1-(4-tert-butylphenyl)-4-(4-(hydroxydiphenylmethyl...)
Affinity DataIC50: 312nMAssay Description:Inhibition of human ERG in L929 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50301391(1-[4-(4-methylphenyl)butyl]-alpha,alpha-diphenyl-4...)
Affinity DataIC50: 396nMAssay Description:Inhibition of human ERG in L929 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50301391(1-[4-(4-methylphenyl)butyl]-alpha,alpha-diphenyl-4...)
Affinity DataIC50: 396nMAssay Description:Inhibition of human ERG in L929 cells at 10 uM by whole cell patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50301392(4-[4-[4-[hydroxy(diphenyl)methyl]-1-piperidinyl]bu...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human ERG in L929 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50301392(4-[4-[4-[hydroxy(diphenyl)methyl]-1-piperidinyl]bu...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human ERG in L929 cells at 10 uM by whole cell patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50301393(1-[4-(4-methylcyclohexyl)butyl]alpha,alpha-dipheny...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ERG in L929 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50017724(CHEMBL127508 | Diphenyl-piperidin-4-yl-methanol | ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ERG in L929 cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50017724(CHEMBL127508 | Diphenyl-piperidin-4-yl-methanol | ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ERG in L929 cells at 10 uM by whole cell patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50301393(1-[4-(4-methylcyclohexyl)butyl]alpha,alpha-dipheny...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ERG in L929 cells at 10 uM by whole cell patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM22874(CHEMBL914 | Allegra | 2-(4-{1-hydroxy-4-[4-(hydrox...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ERG in L929 cells at 10 uM by whole cell patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H1 receptor(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50301397([1-(4-Methyl-benzyl)-piperidin-4-yl]-diphenyl-meth...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]pyrilamine from human recombinant histamine H1 receptor expressed in CHO cell by Betaplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H1 receptor(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50301394(methyl 4-(4-(4-(hydroxydiphenylmethyl)piperidin-1-...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]pyrilamine from human recombinant histamine H1 receptor expressed in CHO cell by Betaplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H1 receptor(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM22874(CHEMBL914 | Allegra | 2-(4-{1-hydroxy-4-[4-(hydrox...)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]pyrilamine from human recombinant histamine H1 receptor expressed in CHO cell by Betaplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H1 receptor(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50301391(1-[4-(4-methylphenyl)butyl]-alpha,alpha-diphenyl-4...)
Affinity DataKi:  39nMAssay Description:Displacement of [3H]pyrilamine from human recombinant histamine H1 receptor expressed in CHO cell by Betaplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H1 receptor(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50017376(1-(4-tert-butylphenyl)-4-(4-(hydroxydiphenylmethyl...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]pyrilamine from human recombinant histamine H1 receptor expressed in CHO cell by Betaplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H1 receptor(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50301393(1-[4-(4-methylcyclohexyl)butyl]alpha,alpha-dipheny...)
Affinity DataKi:  61nMAssay Description:Displacement of [3H]pyrilamine from human recombinant histamine H1 receptor expressed in CHO cell by Betaplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H1 receptor(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50301398(Diphenyl-[1-(2-p-tolyl-ethyl)-piperidin-4-yl]-meth...)
Affinity DataKi:  64nMAssay Description:Displacement of [3H]pyrilamine from human recombinant histamine H1 receptor expressed in CHO cell by Betaplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H1 receptor(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50301396(Phenyl-[1-(4-p-tolyl-butyl)-piperidin-4-yl]-methan...)
Affinity DataKi:  121nMAssay Description:Displacement of [3H]pyrilamine from human recombinant histamine H1 receptor expressed in CHO cell by Betaplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H1 receptor(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50301399(Diphenyl-[1-(3-p-tolyl-propyl)-piperidin-4-yl]-met...)
Affinity DataKi:  155nMAssay Description:Displacement of [3H]pyrilamine from human recombinant histamine H1 receptor expressed in CHO cell by Betaplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H1 receptor(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50301392(4-[4-[4-[hydroxy(diphenyl)methyl]-1-piperidinyl]bu...)
Affinity DataKi:  203nMAssay Description:Displacement of [3H]pyrilamine from human recombinant histamine H1 receptor expressed in CHO cell by Betaplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H1 receptor(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50017724(CHEMBL127508 | Diphenyl-piperidin-4-yl-methanol | ...)
Affinity DataKi:  659nMAssay Description:Displacement of [3H]pyrilamine from human recombinant histamine H1 receptor expressed in CHO cell by Betaplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H1 receptor(Human)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50301395(1-(4-p-Tolyl-butyl)-piperidine | CHEMBL571073)
Affinity DataKi:  3.20E+3nMAssay Description:Displacement of [3H]pyrilamine from human recombinant histamine H1 receptor expressed in CHO cell by Betaplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed