Compile Data Set for Download or QSAR
Report error Found 106 Enz. Inhib. hit(s) with all data for entry = 50041759
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414575(CHEMBL561128)
Affinity DataIC50: 7.94nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414554(CHEMBL551927)
Affinity DataIC50: 63.1nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414557(CHEMBL562464)
Affinity DataIC50: 63.1nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414559(CHEMBL557110)
Affinity DataIC50: 79.4nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414558(CHEMBL556496)
Affinity DataIC50: 200nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414561(CHEMBL561326)
Affinity DataIC50: 251nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414555(CHEMBL565075)
Affinity DataIC50: 398nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414560(CHEMBL563926)
Affinity DataIC50: 631nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414563(CHEMBL559873)
Affinity DataIC50: 794nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414564(CHEMBL562833)
Affinity DataIC50: 794nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414573(CHEMBL541435)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414571(CHEMBL563563)
Affinity DataIC50: 1.26E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414556(CHEMBL564930)
Affinity DataIC50: 1.26E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414562(CHEMBL554738)
Affinity DataIC50: 1.58E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414574(CHEMBL563580)
Affinity DataIC50: 1.58E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414581(CHEMBL560270)
Affinity DataIC50: 1.58E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414566(CHEMBL563435)
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50370572(SB-277011 | CHEMBL85606)
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50411402(CHEMBL244946)
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414576(CHEMBL554693)
Affinity DataIC50: 2.51E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414579(CHEMBL564948)
Affinity DataIC50: 2.51E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414569(CHEMBL272511)
Affinity DataIC50: 2.51E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414403(CHEMBL560177)
Affinity DataIC50: 3.16E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414565(CHEMBL563274)
Affinity DataIC50: 3.16E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414568(CHEMBL562836)
Affinity DataIC50: 3.16E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414570(CHEMBL563635)
Affinity DataIC50: 3.16E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414567(CHEMBL562948)
Affinity DataIC50: 3.98E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414580(CHEMBL555744)
Affinity DataIC50: 5.01E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414578(CHEMBL558058)
Affinity DataIC50: 6.31E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414987(CHEMBL567919)
Affinity DataIC50: 6.31E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414988(CHEMBL572270)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414572(CHEMBL563860)
Affinity DataIC50: 1.26E+4nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414577(CHEMBL549438)
Affinity DataIC50: 5.01E+4nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50020217(CHEMBL69271 | PHNO,(+) | 4-Propyl-3,4,4a,5,6,10b-h...)
Affinity DataKi:  0.200nMAssay Description:Agonistic activity at DRD3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414563(CHEMBL559873)
Affinity DataKi:  0.631nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Rat)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50331549([11C]-3-(2-oxo-3-(2-(4-(trifluoromethyl)piperidin-...)
Affinity DataKi:  0.794nMAssay Description:Antagonistic activity at rat DRD3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50331549([11C]-3-(2-oxo-3-(2-(4-(trifluoromethyl)piperidin-...)
Affinity DataKi:  0.794nMAssay Description:Antagonistic activity at human DRD3 receptor by filtration binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414574(CHEMBL563580)
Affinity DataKi:  1.26nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414578(CHEMBL558058)
Affinity DataKi:  1.58nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50411402(CHEMBL244946)
Affinity DataKi:  1.58nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414403(CHEMBL560177)
Affinity DataKi:  2.51nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414570(CHEMBL563635)
Affinity DataKi:  2.51nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414572(CHEMBL563860)
Affinity DataKi:  2.51nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414557(CHEMBL562464)
Affinity DataKi:  2.51nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414563(CHEMBL559873)
Affinity DataKi:  3.16nMAssay Description:Binding affinity to human DRD2 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414555(CHEMBL565075)
Affinity DataKi:  3.16nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50370572(SB-277011 | CHEMBL85606)
Affinity DataKi:  3.98nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414572(CHEMBL563860)
Affinity DataKi:  3.98nMAssay Description:Binding affinity to human DRD2 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414566(CHEMBL563435)
Affinity DataKi:  5.01nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414574(CHEMBL563580)
Affinity DataKi:  5.01nMAssay Description:Binding affinity to human DRD2 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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