Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50030769
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301095(4-(4-fluorobenzyloxy)-1-(4-((propylamino)methyl)ph...)
Affinity DataIC50: 2.60nMAssay Description:Displacement of [125I]MCH from human recombinant MCH1R expressed on CHOK1 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301089(1-(4-((dipropylamino)methyl)phenethyl)-4-(4-fluoro...)
Affinity DataIC50: 3.30nMAssay Description:Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301094(4-(4-fluorobenzyloxy)-1-(4-((methyl(propyl)amino)m...)
Affinity DataIC50: 3.5nMAssay Description:Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301092(1-(4-((cyclopentyl(propyl)amino)methyl)phenethyl)-...)
Affinity DataIC50: 3.5nMAssay Description:Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301093(1-(4-((ethyl(propyl)amino)methyl)phenethyl)-4-(4-f...)
Affinity DataIC50: 4.40nMAssay Description:Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301091(4-(4-fluorobenzyloxy)-1-(4-((isobutyl(propyl)amino...)
Affinity DataIC50: 4.90nMAssay Description:Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301086(4-(4-fluorobenzyloxy)-1-(4-(pyrrolidin-1-ylmethyl)...)
Affinity DataIC50: 5nMAssay Description:Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301090(4-(4-fluorobenzyloxy)-1-(4-((isopropyl(propyl)amin...)
Affinity DataIC50: 5.20nMAssay Description:Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301096(4-(4-fluorobenzyloxy)-1-(4-(((2-methoxyethyl)(prop...)
Affinity DataIC50: 5.40nMAssay Description:Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301081(4-(4-fluorobenzyloxy)-1-(4-(2-(pyrrolidin-1-yl)eth...)
Affinity DataIC50: 5.60nMAssay Description:Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301081(4-(4-fluorobenzyloxy)-1-(4-(2-(pyrrolidin-1-yl)eth...)
Affinity DataIC50: 5.60nMAssay Description:Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301088(1-(4-((diethylamino)methyl)phenethyl)-4-(4-fluorob...)
Affinity DataIC50: 5.90nMAssay Description:Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301098(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)
Affinity DataIC50: 7nMAssay Description:Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301099(4-(4-fluorobenzyloxy)-1-(2-(6-((propylamino)methyl...)
Affinity DataIC50: 11nMAssay Description:Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301097(4-(4-fluorobenzyloxy)-1-(4-(((2-fluoroethyl)(propy...)
Affinity DataIC50: 11nMAssay Description:Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301095(4-(4-fluorobenzyloxy)-1-(4-((propylamino)methyl)ph...)
Affinity DataIC50: 20nMAssay Description:Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301098(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)
Affinity DataIC50: 27nMAssay Description:Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301083(4-(4-fluorobenzyloxy)-1-(3-(2-(pyrrolidin-1-yl)eth...)
Affinity DataIC50: 29nMAssay Description:Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301084(4-(4-fluorobenzyloxy)-1-(3-(3-(pyrrolidin-1-yl)pro...)
Affinity DataIC50: 30nMAssay Description:Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301100(4-(4-fluorobenzyloxy)-1-(4-((propylamino)methyl)be...)
Affinity DataIC50: 34nMAssay Description:Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301087(4-(4-fluorobenzyloxy)-1-(4-(pyrrolidin-1-yl)phenet...)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301082(4-(4-fluorobenzyloxy)-1-(3-(2-(pyrrolidin-1-yl)eth...)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301085(4-(4-fluorobenzyloxy)-1-(4-(pyrrolidin-1-ylmethyl)...)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonistic activity against MCH1R expressed on CHOK1 cells assessed as intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301095(4-(4-fluorobenzyloxy)-1-(4-((propylamino)methyl)ph...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human ERG potassium channel 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301098(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of muscarinic M1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301098(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of adenosine receptor A2AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301098(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of histamine H4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301098(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301098(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of histamine H2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301098(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301098(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of kappa-type opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301098(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of mu-type opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301095(4-(4-fluorobenzyloxy)-1-(4-((propylamino)methyl)ph...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of muscarinic M1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301095(4-(4-fluorobenzyloxy)-1-(4-((propylamino)methyl)ph...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of adenosine receptor A2AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301095(4-(4-fluorobenzyloxy)-1-(4-((propylamino)methyl)ph...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of histamine H4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301095(4-(4-fluorobenzyloxy)-1-(4-((propylamino)methyl)ph...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301095(4-(4-fluorobenzyloxy)-1-(4-((propylamino)methyl)ph...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of histamine H2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301095(4-(4-fluorobenzyloxy)-1-(4-((propylamino)methyl)ph...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301095(4-(4-fluorobenzyloxy)-1-(4-((propylamino)methyl)ph...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of kappa-type opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301095(4-(4-fluorobenzyloxy)-1-(4-((propylamino)methyl)ph...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of mu-type opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301098(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of delta-type opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301095(4-(4-fluorobenzyloxy)-1-(4-((propylamino)methyl)ph...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of delta-type opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301098(4-(4-fluorobenzyloxy)-1-(2-(5-((propylamino)methyl...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human ERG potassium channel 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed