Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50030466
TargetPoly [ADP-ribose] polymerase 2(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50296561(N-(2-(6-oxo-6,7,8,9-tetrahydro-3H-pyrrolo[3,2-f]is...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human PARP2 expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50296560(N-(2-(6-oxo-6,7,8,9-tetrahydro-3H-pyrrolo[3,2-f]is...)
Affinity DataIC50: 25nMAssay Description:Inhibition of PARP1 in human HeLa cells by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50296561(N-(2-(6-oxo-6,7,8,9-tetrahydro-3H-pyrrolo[3,2-f]is...)
Affinity DataIC50: 27nMAssay Description:Inhibition of PARP1 in human HeLa cells by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50296560(N-(2-(6-oxo-6,7,8,9-tetrahydro-3H-pyrrolo[3,2-f]is...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human PARP2 expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50296540(1-(2-aminoethyl)-8,9-dihydro-3H-pyrrolo[3,2-f]isoq...)
Affinity DataIC50: 40nMAssay Description:Inhibition of PARP1 in human HeLa cells by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50296552(N-(2-(6-oxo-6,7,8,9-tetrahydro-3H-pyrrolo[3,2-f]is...)
Affinity DataIC50: 41nMAssay Description:Inhibition of PARP1 in human HeLa cells by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50296558(N-(2-(6-oxo-6,7,8,9-tetrahydro-3H-pyrrolo[3,2-f]is...)
Affinity DataIC50: 44nMAssay Description:Inhibition of PARP1 in human HeLa cells by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50296559(N-(2-(6-oxo-6,7,8,9-tetrahydro-3H-pyrrolo[3,2-f]is...)
Affinity DataIC50: 45nMAssay Description:Inhibition of PARP1 in human HeLa cells by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50296549(1-methyl-N-(2-(6-oxo-6,7,8,9-tetrahydro-3H-pyrrolo...)
Affinity DataIC50: 53nMAssay Description:Inhibition of PARP1 in human HeLa cells by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50296562(4-methyl-N-(2-(6-oxo-6,7,8,9-tetrahydro-3H-pyrrolo...)
Affinity DataIC50: 58nMAssay Description:Inhibition of PARP1 in human HeLa cells by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50296550(1-methyl-N-(2-(6-oxo-6,7,8,9-tetrahydro-3H-pyrrolo...)
Affinity DataIC50: 60nMAssay Description:Inhibition of PARP1 in human HeLa cells by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50296541(1-(2-(isopropylamino)ethyl)-8,9-dihydro-3H-pyrrolo...)
Affinity DataIC50: 82nMAssay Description:Inhibition of PARP1 in human HeLa cells by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50296542(1-(2-(cyclohexylamino)ethyl)-8,9-dihydro-3H-pyrrol...)
Affinity DataIC50: 85nMAssay Description:Inhibition of PARP1 in human HeLa cells by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50296557(N-(2-(6-oxo-6,7,8,9-tetrahydro-3H-pyrrolo[3,2-f]is...)
Affinity DataIC50: 97nMAssay Description:Inhibition of PARP1 in human HeLa cells by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50296554(2-(1-methylpiperidin-4-yl)-N-(2-(6-oxo-6,7,8,9-tet...)
Affinity DataIC50: 100nMAssay Description:Inhibition of PARP1 in human HeLa cells by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50296543(1-(2-(benzylamino)ethyl)-8,9-dihydro-3H-pyrrolo[3,...)
Affinity DataIC50: 110nMAssay Description:Inhibition of PARP1 in human HeLa cells by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50296553(N-(2-(6-oxo-6,7,8,9-tetrahydro-3H-pyrrolo[3,2-f]is...)
Affinity DataIC50: 120nMAssay Description:Inhibition of PARP1 in human HeLa cells by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50296555(2-(dimethylamino)-N-(2-(6-oxo-6,7,8,9-tetrahydro-3...)
Affinity DataIC50: 130nMAssay Description:Inhibition of PARP1 in human HeLa cells by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50296548(1-(2-(diethylamino)ethyl)-8,9-dihydro-3H-pyrrolo[3...)
Affinity DataIC50: 130nMAssay Description:Inhibition of PARP1 in human HeLa cells by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50296551(N-(2-(6-oxo-6,7,8,9-tetrahydro-3H-pyrrolo[3,2-f]is...)
Affinity DataIC50: 160nMAssay Description:Inhibition of PARP1 in human HeLa cells by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50296544(1-(2-(oxazol-4-ylmethylamino)ethyl)-8,9-dihydro-3H...)
Affinity DataIC50: 180nMAssay Description:Inhibition of PARP1 in human HeLa cells by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50296556(2-morpholino-N-(2-(6-oxo-6,7,8,9-tetrahydro-3H-pyr...)
Affinity DataIC50: 230nMAssay Description:Inhibition of PARP1 in human HeLa cells by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50296563(4-benzyl-N-(2-(6-oxo-6,7,8,9-tetrahydro-3H-pyrrolo...)
Affinity DataIC50: 230nMAssay Description:Inhibition of PARP1 in human HeLa cells by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50296545(1-(2-((1H-pyrazol-4-yl)methylamino)ethyl)-8,9-dihy...)
Affinity DataIC50: 340nMAssay Description:Inhibition of PARP1 in human HeLa cells by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50296564(3,3-difluoro-N-(2-(6-oxo-6,7,8,9-tetrahydro-3H-pyr...)
Affinity DataIC50: 390nMAssay Description:Inhibition of PARP1 in human HeLa cells by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50296547(1-(2-(quinolin-8-ylmethylamino)ethyl)-8,9-dihydro-...)
Affinity DataIC50: 500nMAssay Description:Inhibition of PARP1 in human HeLa cells by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50296546(1-(2-((1-methyl-1H-pyrazol-4-yl)methylamino)ethyl)...)
Affinity DataIC50: 500nMAssay Description:Inhibition of PARP1 in human HeLa cells by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed