Compile Data Set for Download or QSAR
Report error Found 56 Enz. Inhib. hit(s) with all data for entry = 50028835
TargetBeta-3 adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267987((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)
Affinity DataEC50:  20nMAssay Description:Binding affinity to beta3 adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268077((S)-4-(2-hydroxy-3-(1-(4-methoxyphenyl)-2-methylpr...)
Affinity DataEC50:  7nMAssay Description:Binding affinity to beta3 adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268077((S)-4-(2-hydroxy-3-(1-(4-methoxyphenyl)-2-methylpr...)
Affinity DataEC50:  3nMAssay Description:Binding affinity to beta-1 adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267986((+/-)-1-[(2,3-Dichlorophenyl)oxy]-3-((1,1-dimethyl...)
Affinity DataEC50:  200nMAssay Description:Binding affinity to beta3 adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268076((2S)-1-[(2,3-Dichlorophenyl)oxy]-3-((1,1-dimethyl-...)
Affinity DataEC50:  200nMAssay Description:Binding affinity to beta3 adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268076((2S)-1-[(2,3-Dichlorophenyl)oxy]-3-((1,1-dimethyl-...)
Affinity DataIC50: 1nMAssay Description:Binding affinity to beta2 adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268077((S)-4-(2-hydroxy-3-(1-(4-methoxyphenyl)-2-methylpr...)
Affinity DataIC50: 1.30nMAssay Description:Binding affinity to beta2 adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50161093(CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...)
Affinity DataIC50: 2nMAssay Description:Binding affinity to serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50161093(CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...)
Affinity DataIC50: 3nMAssay Description:Binding affinity to human parathyroid calcium receptor 1 expressed in HEK293 4.0-7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-2 adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267986((+/-)-1-[(2,3-Dichlorophenyl)oxy]-3-((1,1-dimethyl...)
Affinity DataIC50: 21nMAssay Description:Binding affinity to beta2 adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267987((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)
Affinity DataIC50: 21nMAssay Description:Binding affinity to beta2 adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267987((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)
Affinity DataIC50: 21nMAssay Description:Binding affinity to serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267988((+/-)-2-Chloro-6-([3-((1,1-dimethyl-2-[4-(methylox...)
Affinity DataIC50: 23nMAssay Description:Binding affinity to beta2 adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267988((+/-)-2-Chloro-6-([3-((1,1-dimethyl-2-[4-(methylox...)
Affinity DataIC50: 34nMAssay Description:Binding affinity to serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267987((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)
Affinity DataIC50: 36nMAssay Description:Binding affinity to CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50161093(CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...)
Affinity DataIC50: 45nMAssay Description:Binding affinity to CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268077((S)-4-(2-hydroxy-3-(1-(4-methoxyphenyl)-2-methylpr...)
Affinity DataIC50: 61nMAssay Description:Binding affinity to serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268075((2R)-1-[(2,3-Dichlorophenyl)oxy]-3-((1,1-dimethyl-...)
Affinity DataIC50: 68nMAssay Description:Binding affinity to human parathyroid calcium receptor 1 expressed in HEK293 4.0-7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267988((+/-)-2-Chloro-6-([3-((1,1-dimethyl-2-[4-(methylox...)
Affinity DataIC50: 70nMAssay Description:Binding affinity to human parathyroid calcium receptor 1 expressed in HEK293 4.0-7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267988((+/-)-2-Chloro-6-([3-((1,1-dimethyl-2-[4-(methylox...)
Affinity DataIC50: 76nMAssay Description:Binding affinity to CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267987((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)
Affinity DataIC50: 140nMAssay Description:Binding affinity to human parathyroid calcium receptor 1 expressed in HEK293 4.0-7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267986((+/-)-1-[(2,3-Dichlorophenyl)oxy]-3-((1,1-dimethyl...)
Affinity DataIC50: 200nMAssay Description:Binding affinity to human parathyroid calcium receptor 1 expressed in HEK293 4.0-7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50161093(CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...)
Affinity DataIC50: 200nMAssay Description:Binding affinity to norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50161093(CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...)
Affinity DataIC50: 200nMAssay Description:Binding affinity to dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268052((+/-)-1-([1,1-Dimethyl-2-(2-naphthalenyl)ethyl]ami...)
Affinity DataIC50: 210nMAssay Description:Binding affinity to human parathyroid calcium receptor 1 expressed in HEK293 4.0-7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268076((2S)-1-[(2,3-Dichlorophenyl)oxy]-3-((1,1-dimethyl-...)
Affinity DataIC50: 300nMAssay Description:Binding affinity to human parathyroid calcium receptor 1 expressed in HEK293 4.0-7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267987((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)
Affinity DataIC50: 300nMAssay Description:Binding affinity to dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267987((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)
Affinity DataIC50: 300nMAssay Description:Binding affinity to norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268075((2R)-1-[(2,3-Dichlorophenyl)oxy]-3-((1,1-dimethyl-...)
Affinity DataIC50: 300nMAssay Description:Binding affinity to beta2 adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268077((S)-4-(2-hydroxy-3-(1-(4-methoxyphenyl)-2-methylpr...)
Affinity DataIC50: 600nMAssay Description:Binding affinity to norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268074((+/-)-(3-[(2,3-Dichlorophenyl)oxy]propyl)(1,1-dime...)
Affinity DataIC50: 930nMAssay Description:Binding affinity to human parathyroid calcium receptor 1 expressed in HEK293 4.0-7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268054((+/-)-[3-[(2,3-Dichlorophenyl)oxy]-2-(methyloxy)pr...)
Affinity DataIC50: 950nMAssay Description:Binding affinity to human parathyroid calcium receptor 1 expressed in HEK293 4.0-7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267984((+/-)-1-[(2-Chlorophenyl)oxy]-3-((1,1-dimethyl-2-[...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to human parathyroid calcium receptor 1 expressed in HEK293 4.0-7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267985((+/-)-1-[(3-Chlorophenyl)oxy]-3-((1,1-dimethyl-2-[...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to human parathyroid calcium receptor 1 expressed in HEK293 4.0-7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267988((+/-)-2-Chloro-6-([3-((1,1-dimethyl-2-[4-(methylox...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267988((+/-)-2-Chloro-6-([3-((1,1-dimethyl-2-[4-(methylox...)
Affinity DataIC50: 1.10E+3nMAssay Description:Binding affinity to dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268077((S)-4-(2-hydroxy-3-(1-(4-methoxyphenyl)-2-methylpr...)
Affinity DataIC50: 1.20E+3nMAssay Description:Binding affinity to dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268077((S)-4-(2-hydroxy-3-(1-(4-methoxyphenyl)-2-methylpr...)
Affinity DataIC50: 1.26E+3nMAssay Description:Binding affinity to CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268270((+/-)-1-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]ethy...)
Affinity DataIC50: 1.30E+3nMAssay Description:Binding affinity to human parathyroid calcium receptor 1 expressed in HEK293 4.0-7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268101((+/-)-1-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]ethy...)
Affinity DataIC50: 2.30E+3nMAssay Description:Binding affinity to human parathyroid calcium receptor 1 expressed in HEK293 4.0-7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268053((+/-)-1-[(2,3-Dichlorophenyl)oxy]-3-[(1,1-dimethyl...)
Affinity DataIC50: 2.30E+3nMAssay Description:Binding affinity to human parathyroid calcium receptor 1 expressed in HEK293 4.0-7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268051((+/-)-1-((1,1-Dimethyl-3-[4-(methyloxy)phenyl]prop...)
Affinity DataIC50: 2.78E+3nMAssay Description:Binding affinity to human parathyroid calcium receptor 1 expressed in HEK293 4.0-7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50161093(CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...)
Affinity DataIC50: 3.00E+3nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268027((+/-)-1-(Butyloxy)-3-((1,1-dimethyl-2-[4-(methylox...)
Affinity DataIC50: 3.20E+3nMAssay Description:Binding affinity to human parathyroid calcium receptor 1 expressed in HEK293 4.0-7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267987((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)
Affinity DataIC50: 3.50E+3nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268008((+/-)-1-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]ethy...)
Affinity DataIC50: 3.50E+3nMAssay Description:Binding affinity to human parathyroid calcium receptor 1 expressed in HEK293 4.0-7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267988((+/-)-2-Chloro-6-([3-((1,1-dimethyl-2-[4-(methylox...)
Affinity DataIC50: 3.60E+3nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50161093(CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...)
Affinity DataIC50: 4.30E+3nMAssay Description:Binding affinity to beta2 adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268025((+/-)-1-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]ethy...)
Affinity DataIC50: 7.00E+3nMAssay Description:Binding affinity to human parathyroid calcium receptor 1 expressed in HEK293 4.0-7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50268026((+/-)-1-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]ethy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to human parathyroid calcium receptor 1 expressed in HEK293 4.0-7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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