Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50032228
TargetProstate-specific antigen(Human)
Laboratory of Molecular Biology, Medical Research Council

Curated by ChEMBL
LigandPNGBDBM50326051((2R,5S,8S,11R,14S,17S,20S)-14,17-bis((1H-imidazol-...)
Affinity DataKd:  2.90E+3nMAssay Description:Binding affinity to prostrate specific antigenMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII/Tissue factor(Human)
Laboratory of Molecular Biology, Medical Research Council

Curated by ChEMBL
LigandPNGBDBM50326044((2S,5S,8R,11S,14S,17S,20S,23S,26R,29S,32S,35S,38S,...)
Affinity DataIC50: 1.5nMAssay Description:Binding affinity to tissue factor/factor 7aMore data for this Ligand-Target Pair
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PubMed
TargetPlasma kallikrein(Human)
Laboratory of Molecular Biology, Medical Research Council

Curated by ChEMBL
LigandPNGBDBM50326040(CHEMBL1240598)
Affinity DataIC50: 33nMAssay Description:Inhibition of human plasma kallikrein using Z-Phe-Arg-AMC substrate after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin G(Human)
Laboratory of Molecular Biology, Medical Research Council

Curated by ChEMBL
LigandPNGBDBM50326028(CHEMBL1240611)
Affinity DataIC50: 100nMAssay Description:Inhibition of human cathepsin G using N-Suc-Ala-Ala-Phe-Pro-pNA substrate by calorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin G(Human)
Laboratory of Molecular Biology, Medical Research Council

Curated by ChEMBL
LigandPNGBDBM50326029(CHEMBL1240609)
Affinity DataIC50: 100nMAssay Description:Inhibition of human cathepsin G using N-Suc-Ala-Ala-Phe-Pro-pNA substrate by calorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin G(Human)
Laboratory of Molecular Biology, Medical Research Council

Curated by ChEMBL
LigandPNGBDBM50326027(CHEMBL1240612)
Affinity DataIC50: 150nMAssay Description:Inhibition of human cathepsin G using N-Suc-Ala-Ala-Phe-Pro-pNA substrate by calorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin G(Human)
Laboratory of Molecular Biology, Medical Research Council

Curated by ChEMBL
LigandPNGBDBM50326025(CHEMBL1240614)
Affinity DataIC50: 200nMAssay Description:Inhibition of human cathepsin G using N-Suc-Ala-Ala-Phe-Pro-pNA substrate by calorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin G(Human)
Laboratory of Molecular Biology, Medical Research Council

Curated by ChEMBL
LigandPNGBDBM50326024(CHEMBL1240615)
Affinity DataIC50: 200nMAssay Description:Inhibition of human cathepsin G using N-Suc-Ala-Ala-Phe-Pro-pNA substrate by calorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin G(Human)
Laboratory of Molecular Biology, Medical Research Council

Curated by ChEMBL
LigandPNGBDBM50326026(CHEMBL1240613)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human cathepsin G using N-Suc-Ala-Ala-Phe-Pro-pNA substrate by calorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasma kallikrein(Human)
Laboratory of Molecular Biology, Medical Research Council

Curated by ChEMBL
LigandPNGBDBM50326042(CHEMBL1240595)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human plasma kallikrein using Z-Phe-Arg-AMC substrate after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasma kallikrein(Human)
Laboratory of Molecular Biology, Medical Research Council

Curated by ChEMBL
LigandPNGBDBM50326037(CHEMBL1240604)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human plasma kallikrein using Z-Phe-Arg-AMC substrate after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKallikrein-2(Human)
Laboratory of Molecular Biology, Medical Research Council

Curated by ChEMBL
LigandPNGBDBM50326050(CHEMBL1240617)
Affinity DataIC50: 3.40E+3nMAssay Description:Binding affinity to human kallikrein 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasma kallikrein(Human)
Laboratory of Molecular Biology, Medical Research Council

Curated by ChEMBL
LigandPNGBDBM50326021(CHEMBL1240699)
Affinity DataIC50: 5.71E+3nMAssay Description:Inhibition of human plasma kallikrein using Z-Phe-Arg-AMC substrate after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasma kallikrein(Human)
Laboratory of Molecular Biology, Medical Research Council

Curated by ChEMBL
LigandPNGBDBM50326022(CHEMBL1240698)
Affinity DataIC50: 7.18E+3nMAssay Description:Inhibition of human plasma kallikrein using Z-Phe-Arg-AMC substrate after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasma kallikrein(Human)
Laboratory of Molecular Biology, Medical Research Council

Curated by ChEMBL
LigandPNGBDBM50326020((2R,3S,6S,9S,12S,15S,18R,21S,27S)-6-((1H-indol-3-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human plasma kallikrein using Z-Phe-Arg-AMC substrate after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasma kallikrein(Human)
Laboratory of Molecular Biology, Medical Research Council

Curated by ChEMBL
LigandPNGBDBM50326023((2R,5S,8S,11S,14S,17S)-1-((S)-2-((5R,8S,14S,17S,20...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human plasma kallikrein using Z-Phe-Arg-AMC substrate after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasma kallikrein(Human)
Laboratory of Molecular Biology, Medical Research Council

Curated by ChEMBL
LigandPNGBDBM50326019((2R,5S,8S,11S,14S,17S)-1-((S)-2-((5R,8S,11S,14S,17...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human plasma kallikrein using Z-Phe-Arg-AMC substrate after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Laboratory of Molecular Biology, Medical Research Council

Curated by ChEMBL
LigandPNGBDBM50326047((6S,9R,12R)-1-((R)-1-((R)-2-((S)-1-((S)-5-amino-2-...)
Affinity DataIC50: 1.60E+4nMAssay Description:Binding affinity to pancreatic lipaseMore data for this Ligand-Target Pair
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PubMed
TargetAngiotensin-converting enzyme 2(Human)
Laboratory of Molecular Biology, Medical Research Council

Curated by ChEMBL
LigandPNGBDBM50326045(CHEMBL1240682)
Affinity DataKi:  2.80nMAssay Description:Binding affinity to angiotensin converting enzyme 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDeoxyribonuclease-2-alpha(Human)
Laboratory of Molecular Biology, Medical Research Council

Curated by ChEMBL
LigandPNGBDBM50326048((2R,5S,8S,11S,14S,17S,20S,23S,26S,29S,32S,35R)-8,1...)
Affinity DataKi:  200nMAssay Description:Binding affinity to Dnase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Laboratory of Molecular Biology, Medical Research Council

Curated by ChEMBL
LigandPNGBDBM50326049((3S,6S,9S,12S,15S,18S,21S,24R)-1-((S)-1-((R)-2-ami...)
Affinity DataKi:  400nMAssay Description:Binding affinity to urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Laboratory of Molecular Biology, Medical Research Council

Curated by ChEMBL
LigandPNGBDBM50326043((2R,5S,8S,11S,14S,17S)-11-((1H-imidazol-5-yl)methy...)
Affinity DataKi:  6.70E+3nMAssay Description:Binding affinity to urokinase-type plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Laboratory of Molecular Biology, Medical Research Council

Curated by ChEMBL
LigandPNGBDBM50326046((2S,5S,8S,11R,14R,17S)-17,21-diamino-8-(4-hydroxyb...)
Affinity DataKi:  3.00E+4nMAssay Description:Binding affinity to ErbB-2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed