Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50028680
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut FüR Pharmazeutische Und Medizinische Chemie Der UniversitäT MüNster

Curated by ChEMBL
LigandPNGBDBM50259004(1'-[4-Fluorobenzyl]-3H-spiro[[2]benzofuran-1,4'pip...)
Affinity DataKi:  0.180nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane by solid scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut FüR Pharmazeutische Und Medizinische Chemie Der UniversitäT MüNster

Curated by ChEMBL
LigandPNGBDBM50259001(1'-(4-Fluorobenzyl)-3-methoxy-3H-spiro[[2]benzofur...)
Affinity DataKi:  0.790nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane by solid scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut FüR Pharmazeutische Und Medizinische Chemie Der UniversitäT MüNster

Curated by ChEMBL
LigandPNGBDBM50258915(1'-(4-Fluorobenzyl)-3H-spiro[[2]benzofuran-1,4'-pi...)
Affinity DataKi:  0.860nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane by solid scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut FüR Pharmazeutische Und Medizinische Chemie Der UniversitäT MüNster

Curated by ChEMBL
LigandPNGBDBM50108659(1'-benzyl-3-methoxyspiro[1,3-dihydroisobenzofuran-...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane by solid scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut FüR Pharmazeutische Und Medizinische Chemie Der UniversitäT MüNster

Curated by ChEMBL
LigandPNGBDBM50258916(3-Allyl-1'-(4-fluorobenzyl)-3H-spiro[[2]benzofuran...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane by solid scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut FüR Pharmazeutische Und Medizinische Chemie Der UniversitäT MüNster

Curated by ChEMBL
LigandPNGBDBM50259002(1'-(4-Fluorobenzyl)-3H-spiro[[2]benzofuran-1,4'-pi...)
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane by solid scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut FüR Pharmazeutische Und Medizinische Chemie Der UniversitäT MüNster

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane by solid scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut FüR Pharmazeutische Und Medizinische Chemie Der UniversitäT MüNster

Curated by ChEMBL
LigandPNGBDBM50259003(1'-(4-fluorobenzyl)-3H-spiro[isobenzofuran-1,4'-pi...)
Affinity DataKi:  7.70nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane by solid scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut FüR Pharmazeutische Und Medizinische Chemie Der UniversitäT MüNster

Curated by ChEMBL
LigandPNGBDBM81982(CAS_97-39-2 | cid_7333 | Di-o-tolylguanidine | DIT...)
Affinity DataKi:  61nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane by solid scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed