Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 3139
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

LigandPNGBDBM28574(3-amino-N-[1-(naphthalene-1-sulfonyl)-1H-indazol-6...)
Affinity DataKi:  0.5nM ΔG°:  -52.6kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

LigandPNGBDBM28575(3-(methylamino)-N-[1-(naphthalene-1-sulfonyl)-1H-i...)
Affinity DataKi:  1.20nM ΔG°:  -50.4kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

LigandPNGBDBM28580(N-[1-(naphthalene-1-sulfonyl)-1H-indazol-6-yl]pipe...)
Affinity DataKi:  1.30nM ΔG°:  -50.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

LigandPNGBDBM28576(3-(dimethylamino)-N-[1-(naphthalene-1-sulfonyl)-1H...)
Affinity DataKi:  1.80nM ΔG°:  -49.4kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

LigandPNGBDBM28577(3-(diethylamino)-N-[1-(naphthalene-1-sulfonyl)-1H-...)
Affinity DataKi:  2.10nM ΔG°:  -49.0kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

LigandPNGBDBM28579(N-[1-(naphthalene-1-sulfonyl)-1H-indazol-6-yl]pipe...)
Affinity DataKi:  2.30nM ΔG°:  -48.8kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

LigandPNGBDBM28572(3-amino-N-[1-(naphthalene-1-sulfonyl)-1H-indazol-4...)
Affinity DataKi:  7.90nM ΔG°:  -45.8kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

LigandPNGBDBM28578(N-[1-(naphthalene-1-sulfonyl)-1H-indazol-6-yl]-3-(...)
Affinity DataKi:  15nM ΔG°:  -44.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

LigandPNGBDBM28581(1-(naphthalene-1-sulfonyl)-N-(piperidin-4-ylmethyl...)
Affinity DataKi:  18nM ΔG°:  -43.8kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

LigandPNGBDBM28573(3-amino-N-[1-(naphthalene-1-sulfonyl)-1H-indazol-5...)
Affinity DataKi:  50nM ΔG°:  -41.3kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Wyeth Research

LigandPNGBDBM28579(N-[1-(naphthalene-1-sulfonyl)-1H-indazol-6-yl]pipe...)
Affinity DataKi:  130nM ΔG°:  -38.9kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Wyeth Research

LigandPNGBDBM28574(3-amino-N-[1-(naphthalene-1-sulfonyl)-1H-indazol-6...)
Affinity DataKi:  155nM ΔG°:  -38.5kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Wyeth Research

LigandPNGBDBM28580(N-[1-(naphthalene-1-sulfonyl)-1H-indazol-6-yl]pipe...)
Affinity DataKi:  174nM ΔG°:  -38.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Wyeth Research

LigandPNGBDBM28580(N-[1-(naphthalene-1-sulfonyl)-1H-indazol-6-yl]pipe...)
Affinity DataKi:  1.80E+3nM ΔG°:  -32.5kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Wyeth Research

LigandPNGBDBM28579(N-[1-(naphthalene-1-sulfonyl)-1H-indazol-6-yl]pipe...)
Affinity DataKi: >2.00E+3nM ΔG°: >-32.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Wyeth Research

LigandPNGBDBM28574(3-amino-N-[1-(naphthalene-1-sulfonyl)-1H-indazol-6...)
Affinity DataKi: >2.00E+3nM ΔG°: >-32.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Wyeth Research

LigandPNGBDBM28574(3-amino-N-[1-(naphthalene-1-sulfonyl)-1H-indazol-6...)
Affinity DataKi: >2.00E+3nM ΔG°: >-32.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Wyeth Research

LigandPNGBDBM28579(N-[1-(naphthalene-1-sulfonyl)-1H-indazol-6-yl]pipe...)
Affinity DataKi: >2.00E+3nM ΔG°: >-32.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Wyeth Research

LigandPNGBDBM28580(N-[1-(naphthalene-1-sulfonyl)-1H-indazol-6-yl]pipe...)
Affinity DataKi: >2.00E+3nM ΔG°: >-32.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth Research

LigandPNGBDBM28574(3-amino-N-[1-(naphthalene-1-sulfonyl)-1H-indazol-6...)
Affinity DataKi: >2.00E+3nM ΔG°: >-32.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth Research

LigandPNGBDBM28579(N-[1-(naphthalene-1-sulfonyl)-1H-indazol-6-yl]pipe...)
Affinity DataKi: >2.00E+3nM ΔG°: >-32.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth Research

LigandPNGBDBM28580(N-[1-(naphthalene-1-sulfonyl)-1H-indazol-6-yl]pipe...)
Affinity DataKi: >2.00E+3nM ΔG°: >-32.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Wyeth Research

LigandPNGBDBM28574(3-amino-N-[1-(naphthalene-1-sulfonyl)-1H-indazol-6...)
Affinity DataKi: >2.00E+3nM ΔG°: >-32.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Wyeth Research

LigandPNGBDBM28579(N-[1-(naphthalene-1-sulfonyl)-1H-indazol-6-yl]pipe...)
Affinity DataKi: >2.00E+3nM ΔG°: >-32.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Wyeth Research

LigandPNGBDBM28574(3-amino-N-[1-(naphthalene-1-sulfonyl)-1H-indazol-6...)
Affinity DataKi:  5.10E+3nM ΔG°:  -29.9kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

LigandPNGBDBM28580(N-[1-(naphthalene-1-sulfonyl)-1H-indazol-6-yl]pipe...)
Affinity DataKi:  5.60E+3nM ΔG°:  -29.7kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Wyeth Research

LigandPNGBDBM28580(N-[1-(naphthalene-1-sulfonyl)-1H-indazol-6-yl]pipe...)
Affinity DataKi:  5.80E+3nM ΔG°:  -29.6kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

LigandPNGBDBM28574(3-amino-N-[1-(naphthalene-1-sulfonyl)-1H-indazol-6...)
Affinity DataKi:  6.40E+3nM ΔG°:  -29.3kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Wyeth Research

LigandPNGBDBM28579(N-[1-(naphthalene-1-sulfonyl)-1H-indazol-6-yl]pipe...)
Affinity DataKi:  6.90E+3nM ΔG°:  -29.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

LigandPNGBDBM28579(N-[1-(naphthalene-1-sulfonyl)-1H-indazol-6-yl]pipe...)
Affinity DataKi:  8.50E+3nM ΔG°:  -28.7kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed