Compile Data Set for Download or QSAR
Report error Found 90 Enz. Inhib. hit(s) with all data for entry = 3345
TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31673(imidazole-dioxolane, 25)
Affinity DataIC50: 280nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31653(CHEMBL421109 | imidazole-dioxolane, 5)
Affinity DataIC50: 330nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 2(Rat)
Queen'S University

LigandPNGBDBM31673(imidazole-dioxolane, 25)
Affinity DataIC50: 500nMpH: 7.4Assay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31671(imidazole-dioxolane, 23)
Affinity DataIC50: 590nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31677(imidazole-dioxolane, 29)
Affinity DataIC50: 670nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31659(imidazole-dioxolane, 11)
Affinity DataIC50: 700nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31679(imidazole-dioxolane, 2)
Affinity DataIC50: 800nMpH: 7.4Assay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31665(imidazole-dioxolane, 17)
Affinity DataIC50: 900nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31664(imidazole-dioxolane, 16)
Affinity DataIC50: 940nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31652(imidazole-dioxolane, 3)
Affinity DataIC50: 1.03E+3nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31682(imidazole-dioxolane, 32)
Affinity DataIC50: 1.20E+3nMpH: 7.4Assay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31675(imidazole-dioxolane, 27)
Affinity DataIC50: 1.33E+3nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A1(Rat)
Queen'S University

LigandPNGBDBM31657(imidazole-dioxolane, 9)
Affinity DataIC50: 1.40E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31668(imidazole-dioxolane, 20)
Affinity DataIC50: 1.40E+3nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31657(imidazole-dioxolane, 9)
Affinity DataIC50: 1.59E+3nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 2(Rat)
Queen'S University

LigandPNGBDBM31671(imidazole-dioxolane, 23)
Affinity DataIC50: 1.60E+3nMpH: 7.4Assay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 2(Rat)
Queen'S University

LigandPNGBDBM31677(imidazole-dioxolane, 29)
Affinity DataIC50: 1.70E+3nMpH: 7.4Assay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31687(imidazole-dioxolane, 37)
Affinity DataIC50: 1.73E+3nMpH: 7.4Assay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31669(imidazole-dioxolane, 21)
Affinity DataIC50: 1.80E+3nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A1(Rat)
Queen'S University

LigandPNGBDBM31665(imidazole-dioxolane, 17)
Affinity DataIC50: 1.80E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A1(Rat)
Queen'S University

LigandPNGBDBM31669(imidazole-dioxolane, 21)
Affinity DataIC50: 2.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A1(Rat)
Queen'S University

LigandPNGBDBM31652(imidazole-dioxolane, 3)
Affinity DataIC50: 2.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31674(imidazole-dioxolane, 26)
Affinity DataIC50: 2.00E+3nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31663(imidazole-dioxolane, 15)
Affinity DataIC50: 2.10E+3nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31658(imidazole-dioxolane, 10)
Affinity DataIC50: 2.10E+3nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A1(Rat)
Queen'S University

LigandPNGBDBM31658(imidazole-dioxolane, 10)
Affinity DataIC50: 2.10E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A1(Rat)
Queen'S University

LigandPNGBDBM31681(imidazole-dioxolane, 31)
Affinity DataIC50: 2.20E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31661(imidazole-dioxolane, 13)
Affinity DataIC50: 2.20E+3nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 2(Rat)
Queen'S University

LigandPNGBDBM31658(imidazole-dioxolane, 10)
Affinity DataIC50: 2.40E+3nMpH: 7.4Assay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 2(Rat)
Queen'S University

LigandPNGBDBM31659(imidazole-dioxolane, 11)
Affinity DataIC50: 2.50E+3nMpH: 7.4Assay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A1(Rat)
Queen'S University

LigandPNGBDBM31664(imidazole-dioxolane, 16)
Affinity DataIC50: 2.80E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31660(imidazole-dioxolane, 12)
Affinity DataIC50: 2.80E+3nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 2(Rat)
Queen'S University

LigandPNGBDBM31687(imidazole-dioxolane, 37)
Affinity DataIC50: 3.30E+3nMpH: 7.4Assay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A1(Rat)
Queen'S University

LigandPNGBDBM31672(imidazole-dioxolane, 24)
Affinity DataIC50: 3.40E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31684(imidazole-dioxolane, 34)
Affinity DataIC50: 3.50E+3nMpH: 7.4Assay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31672(imidazole-dioxolane, 24)
Affinity DataIC50: 3.50E+3nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31685(imidazole-dioxolane, 35)
Affinity DataIC50: 3.60E+3nMpH: 7.4Assay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2E1(Rat)
Queen'S University

LigandPNGBDBM31682(imidazole-dioxolane, 32)
Affinity DataIC50: 3.60E+3nMpH: 7.4Assay Description:CYP2E1 hydroxylation of p-nitrophenol was determined by the spectrophotometric measurement of 4-nitrocatechol. Briefly, reaction mixture consisting o...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A1(Rat)
Queen'S University

LigandPNGBDBM31682(imidazole-dioxolane, 32)
Affinity DataIC50: 4.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31654(CHEMBL368045 | imidazole-dioxolane, 6)
Affinity DataIC50: 4.00E+3nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31655(CHEMBL179494 | imidazole-dioxolane, 7)
Affinity DataIC50: 4.00E+3nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 2(Rat)
Queen'S University

LigandPNGBDBM31682(imidazole-dioxolane, 32)
Affinity DataIC50: 4.40E+3nMpH: 7.4Assay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31666(imidazole-dioxolane, 18)
Affinity DataIC50: 5.00E+3nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 2(Rat)
Queen'S University

LigandPNGBDBM31661(imidazole-dioxolane, 13)
Affinity DataIC50: 5.00E+3nMpH: 7.4Assay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31662(imidazole-dioxolane, 14)
Affinity DataIC50: 6.00E+3nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31667(imidazole-dioxolane, 19)
Affinity DataIC50: 6.00E+3nMpH: 7.4 T: 2°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 2(Rat)
Queen'S University

LigandPNGBDBM31655(CHEMBL179494 | imidazole-dioxolane, 7)
Affinity DataIC50: 6.00E+3nMpH: 7.4Assay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A1(Rat)
Queen'S University

LigandPNGBDBM31677(imidazole-dioxolane, 29)
Affinity DataIC50: 6.90E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A1(Rat)
Queen'S University

LigandPNGBDBM31656(imidazole-dioxolane, 8)
Affinity DataIC50: 7.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeme oxygenase 2(Rat)
Queen'S University

LigandPNGBDBM31657(imidazole-dioxolane, 9)
Affinity DataIC50: 7.00E+3nMpH: 7.4Assay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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