Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 3119
LigandPNGBDBM28322((1R,2S)-1-{[4-(3-methoxyprop-1-yn-1-yl)benzene][2-...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM28308((2S)-2-{[4-(4-chlorophenyl)benzene](methyl)sulfona...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM28309((2R)-2-{[4-(4-chlorophenyl)benzene](cyclopropylmet...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM28310((2R)-2-{[4-(4-chlorophenyl)benzene](cyclohexylmeth...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM28311((2R)-2-{benzyl[4-(4-chlorophenyl)benzene]sulfonami...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM28321((1R,2S)-1-{[4-(3-hydroxyprop-1-yn-1-yl)benzene][2-...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM28320((1R,2S)-1-{[2-(2-oxopyrrolidin-1-yl)ethyl][4-(pyri...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28315((2R)-2-{[4-(4-chlorophenyl)benzene][2-(2-oxopyrrol...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM28339((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(7H-purin...)
Affinity DataIC50: 71nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM28337((1R,2S)-1-{[4-(4-chlorophenyl)benzene]({2-[4-(meth...)
Affinity DataIC50: 73nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM28327((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(3-methox...)
Affinity DataIC50: 78nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM28340((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(9H-purin...)
Affinity DataIC50: 170nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM28332((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(1H-1,2,4...)
Affinity DataIC50: 180nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28326((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(2-oxo-1,...)
Affinity DataIC50: 180nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28333((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(4H-1,2,4...)
Affinity DataIC50: 190nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28314((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(2-oxopyr...)
Affinity DataIC50: 200nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28325((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(2-oxopip...)
Affinity DataIC50: 210nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28324((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(2-oxo-1,...)
Affinity DataIC50: 220nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28338((1R,2S)-1-{[4-(4-chlorophenyl)benzene]({2-[5-(meth...)
Affinity DataIC50: 230nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28334((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(2H-1,2,3...)
Affinity DataIC50: 260nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28335((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(1H-1,2,3...)
Affinity DataIC50: 270nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28336((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(1H-1,2,3...)
Affinity DataIC50: 270nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28329((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(pyridin-...)
Affinity DataIC50: 290nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28323((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(2,5-diox...)
Affinity DataIC50: 310nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28331((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(1H-imida...)
Affinity DataIC50: 320nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28328((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(pyridin-...)
Affinity DataIC50: 750nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28330((1R,2S)-1-{[4-(4-chlorophenyl)benzene][2-(pyridin-...)
Affinity DataIC50: 820nMAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28316((1R,2S)-1-({[4-(4-chlorophenyl)-1,2,3,6-tetrahydro...)
Affinity DataIC50: 880nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM28317((1R,2S)-1-{[6-(4-chlorophenyl)pyridine-3-][2-(2-ox...)
Affinity DataIC50: 1.10E+3nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28313((2R)-2-{[4-(4-chlorophenyl)benzene][2-(2-oxopyrrol...)
Affinity DataIC50: 1.60E+3nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28306((2R)-2-{[4-(4-chlorophenyl)benzene]sulfonamido}-3-...)
Affinity DataIC50: 3.20E+3nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28319((1R,2S)-1-{[4-(4-acetamidophenyl)benzene][2-(2-oxo...)
Affinity DataIC50: 4.50E+3nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM28318((1R,2S)-1-({4-[4-(dimethylamino)phenyl]benzene}[2-...)
Affinity DataIC50: 6.60E+3nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28312((2R)-2-{[4-(4-chlorophenyl)benzene](2-phenylethyl)...)
Affinity DataIC50: 7.30E+3nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM28307((2R)-2-{[4-(4-chlorophenyl)benzene](methyl)sulfona...)
Affinity DataIC50: 8.00E+3nMpH: 7.5 T: 2°CAssay Description:The ADAMTS-5 (Aggrecanase-2) assay was performed using fluorescent peptide substrate WAAG-3R and the recombinant Agg-2 pre-incubated with various con...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed