Compile Data Set for Download or QSAR
Report error Found 52 Enz. Inhib. hit(s) with all data for entry = 50000813
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010161(CHEMBL2370397 | [16-Acetylamino-4-carbamoyl-13-(3-...)
Affinity DataIC50: 355nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010193(CHEMBL2370407 | [16-Acetylamino-4-carbamoyl-13-(3-...)
Affinity DataIC50: 370nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50040751([(4S,7S,13R,16S)-16-Acetylamino-4-carbamoyl-13-(3-...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50421884(CHEMBL2110309)
Affinity DataIC50: 4.12E+3nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010171(CHEMBL2370393 | [16-Acetylamino-4-carbamoyl-13-(3-...)
Affinity DataIC50: 7.97E+3nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010179(1N-[1-formyl-(1S)-ethylcarbamoylmethylcarbamoylmet...)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010177(CHEMBL2370394 | [19-Acetylamino-4-carbamoyl-13-(3-...)
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010176(CHEMBL107009 | [16-Acetylamino-4-carbamoyl-13-(3-g...)
Affinity DataIC50: 1.62E+4nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010187(CHEMBL320288 | [19-Acetylamino-4-carbamoyl-16-(3-g...)
Affinity DataIC50: 3.27E+4nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010189(CHEMBL2370392 | 3-[4-amino(imino)methylamino-1-met...)
Affinity DataIC50: 4.05E+4nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010175(CHEMBL107169 | [19-Acetylamino-4-carbamoyl-13-(3-g...)
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010166(CHEMBL2370399 | [16-Acetylamino-13-(4-amino-butyl)...)
Affinity DataIC50: 5.53E+4nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010184(CHEMBL321152 | 3-[4-amino(imino)methylamino-1-meth...)
Affinity DataIC50: 5.55E+4nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50003326(CHEMBL420106 | 3-[4-amino(imino)methylamino-1-meth...)
Affinity DataIC50: 6.72E+4nMAssay Description:Inhibition of thrombin-stimulated platelet aggregation in dogsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010168(CHEMBL430862 | 3-[5-amino(imino)methylamino-1-meth...)
Affinity DataIC50: 6.82E+4nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010183(CHEMBL353203 | [16-Acetylamino-4-carbamoyl-13-(3-g...)
Affinity DataIC50: 7.34E+4nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010182(CHEMBL107910 | 3-[4-amino(imino)methylamino-1-meth...)
Affinity DataIC50: 7.59E+4nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010178(CHEMBL2370398 | [4-Acetyl-16-acetylamino-13-(2-car...)
Affinity DataIC50: 8.20E+4nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50003326(CHEMBL420106 | 3-[4-amino(imino)methylamino-1-meth...)
Affinity DataIC50: 9.13E+4nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010173(CHEMBL104274 | 4-[4-amino(imino)methylamino-1-meth...)
Affinity DataIC50: 9.70E+4nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010192(CHEMBL107629 | 3-[4-amino(imino)methylamino-1-meth...)
Affinity DataIC50: 1.02E+5nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010188(CHEMBL105092 | 3-[4-amino(imino)methylamino-1-[4-a...)
Affinity DataIC50: 1.13E+5nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010160(CHEMBL106629 | 3-[4-amino(imino)methylamino-1-meth...)
Affinity DataIC50: 1.38E+5nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010174(CHEMBL104534 | 3-[4-amino(imino)methylamino-1-meth...)
Affinity DataIC50: 1.38E+5nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010194(CHEMBL2370405 | 16-(2-Acetylamino-6-amino-hexanoyl...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010165(CHEMBL107339 | 3-[1-[5-amino(imino)methylamino-2-m...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010180(CHEMBL107340 | 3-[1-[4-amino(imino)methylamino-1-m...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010164(CHEMBL320678 | 2-[4-amino(imino)methylamino-1-meth...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010191(CHEMBL107803 | 4-[5-amino-1-methylcarboxamido-(1S)...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010172(CHEMBL419909 | 3-[1-carbamoyl-2-hydroxy-(1S)-ethyl...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010163(CHEMBL106251 | 3-[4-amino(imino)methylamino-1-meth...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50040751([(4S,7S,13R,16S)-16-Acetylamino-4-carbamoyl-13-(3-...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010169(CHEMBL104018 | 3-[5-amino-1-methylcarboxamido-(1S)...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010156(CHEMBL2370391 | 3-[1-carbamoyl-2-hydroxy-(1S)-ethy...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010158(CHEMBL325332 | 3-[4-amino(imino)methylamino-1-meth...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010162(CHEMBL2370401 | [16-Acetylamino-4-carbamoyl-13-(3-...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010186(CHEMBL106724 | 3-[4-amino(imino)methylamino-1-meth...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010170(CHEMBL104012 | 4-[4-amino(imino)methylamino-1-meth...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010190(CHEMBL104428 | 1N-[1-carbamoyl-2-hydroxy-(1S)-ethy...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50421885(CHEMBL2111672)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010167(1N-[1-[5-amino-1-formyl-(1S)-pentylcarbamoyl]-(1S)...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010185(CHEMBL2370400 | 16-Acetylamino-7-carbamoylmethyl-1...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010181(CHEMBL2370402 | [16-Acetylamino-4-carbamoyl-13-(4-...)
Affinity DataIC50: 3.85E+5nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010161(CHEMBL2370397 | [16-Acetylamino-4-carbamoyl-13-(3-...)
Affinity DataKi:  58nMAssay Description:Inhibition of 125[I] Fibrinogen binding to isolated purified human fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010161(CHEMBL2370397 | [16-Acetylamino-4-carbamoyl-13-(3-...)
Affinity DataKi:  62nMAssay Description:Inhibition of human washed platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50040751([(4S,7S,13R,16S)-16-Acetylamino-4-carbamoyl-13-(3-...)
Affinity DataKi:  720nMAssay Description:Inhibition of 125[I] Fibrinogen binding to isolated purified human fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010176(CHEMBL107009 | [16-Acetylamino-4-carbamoyl-13-(3-g...)
Affinity DataKi:  780nMAssay Description:Inhibition of 125[I] Fibrinogen binding to isolated purified human fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50003326(CHEMBL420106 | 3-[4-amino(imino)methylamino-1-meth...)
Affinity DataKi:  4.20E+3nMAssay Description:Inhibition of 125[I] Fibrinogen binding to isolated purified human fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010187(CHEMBL320288 | [19-Acetylamino-4-carbamoyl-16-(3-g...)
Affinity DataKi:  5.30E+3nMAssay Description:Inhibition of 125[I] Fibrinogen binding to isolated purified human fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals Research and Development

Curated by ChEMBL
LigandPNGBDBM50010184(CHEMBL321152 | 3-[4-amino(imino)methylamino-1-meth...)
Affinity DataKi: <1.00E+4nMAssay Description:Inhibition of human washed platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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