Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50028206
TargetMelatonin receptor type 1B(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266433(N-(2-{5-Methoxy-2-[(2,3-dihydro-1H-indol-1yl)methy...)
Affinity DataKi:  0.00100nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266405(N-(3-(3-methoxyphenyl)-3-(naphthalen-2-yl)propyl)a...)
Affinity DataKi:  0.110nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50240952(N-(8-Methoxy-10,11-dihydro-5H-dibenzo[a,d]cyclohep...)
Affinity DataKi:  0.160nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50114704(N-{2-[5-Methoxy-2-(3-methoxy-benzyl)-benzofuran-3-...)
Affinity DataKi:  0.25nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50240440(CHEMBL285718 | 4-P-PDOT | N-(4-Phenyl-1,2,3,4-tetr...)
Affinity DataKi:  0.460nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50086001(N-[2-(11-Methoxy-6,7-dihydro-5H-benzo[3,4]azepino[...)
Affinity DataKi:  0.5nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266354(N-(2-((1R,3R)-7-methoxy-3-phenyl-1,2,3,4-tetrahydr...)
Affinity DataKi:  0.900nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266430(N-(2-{5-Methoxy-2-[(2,3-dihydro-1H-indol-1yl)methy...)
Affinity DataKi:  1.10nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50240952(N-(8-Methoxy-10,11-dihydro-5H-dibenzo[a,d]cyclohep...)
Affinity DataKi:  1.40nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50241105((E)-N-[3-(3-methoxyphenyl)-3-phenyl-2-propenyl]ace...)
Affinity DataKi:  2.5nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266434(N-(2-{5-Methoxy-2-[(5-methoxy-2,3-dihydro-1H-indol...)
Affinity DataKi:  5.80nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266434(N-(2-{5-Methoxy-2-[(5-methoxy-2,3-dihydro-1H-indol...)
Affinity DataKi:  7.10nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266431(N-(2-{5-Methoxy-2-[(2,3-dihydro-1H-indol-1yl)methy...)
Affinity DataKi:  8nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50240442(N-[1-(4-Chloro-benzyl)-4-methoxy-1H-indol-2-ylmeth...)
Affinity DataKi:  9nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266408(N-(2-{5-Methoxy-2-[(2-methyl-2,3-dihydro-1H-indol-...)
Affinity DataKi:  14nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266432(N-(2-{5-Methoxy-2-[2,3-dihydro-1H-indol-1yl)methyl...)
Affinity DataKi:  14.5nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266450(N-(2-{5-Methoxy-2-[(5-methyl-2,3-dihydro-1H-indol-...)
Affinity DataKi:  15nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266452(N-{2-[5-Methoxy-2-(pyrrolidin-1ylmethyl)-1H-indol-...)
Affinity DataKi:  25nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266453(N-(2-{5-Methoxy-2-[(6-nitro-2,3-dihydro-1H-indol-1...)
Affinity DataKi:  26nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50114704(N-{2-[5-Methoxy-2-(3-methoxy-benzyl)-benzofuran-3-...)
Affinity DataKi:  27nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266451(N-(2-{2-[(5-Bromo-2,3-dihydro-1H-indol-1yl)methyl)...)
Affinity DataKi:  30nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266432(N-(2-{5-Methoxy-2-[2,3-dihydro-1H-indol-1yl)methyl...)
Affinity DataKi:  38nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266431(N-(2-{5-Methoxy-2-[(2,3-dihydro-1H-indol-1yl)methy...)
Affinity DataKi:  41nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266450(N-(2-{5-Methoxy-2-[(5-methyl-2,3-dihydro-1H-indol-...)
Affinity DataKi:  41nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50240440(CHEMBL285718 | 4-P-PDOT | N-(4-Phenyl-1,2,3,4-tetr...)
Affinity DataKi:  59nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266406(N-[2-(9-Methoxy-13a,14-dihydro-6H,13H-pyrazino[1,2...)
Affinity DataKi:  65nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50086001(N-[2-(11-Methoxy-6,7-dihydro-5H-benzo[3,4]azepino[...)
Affinity DataKi:  66nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266451(N-(2-{2-[(5-Bromo-2,3-dihydro-1H-indol-1yl)methyl)...)
Affinity DataKi:  85nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266454(N-(2-{2-[(6-Amino-2,3-dihydro-1H-indol-1yl)methyl]...)
Affinity DataKi:  110nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266430(N-(2-{5-Methoxy-2-[(2,3-dihydro-1H-indol-1yl)methy...)
Affinity DataKi:  114nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266454(N-(2-{2-[(6-Amino-2,3-dihydro-1H-indol-1yl)methyl]...)
Affinity DataKi:  118nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266452(N-{2-[5-Methoxy-2-(pyrrolidin-1ylmethyl)-1H-indol-...)
Affinity DataKi:  121nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266405(N-(3-(3-methoxyphenyl)-3-(naphthalen-2-yl)propyl)a...)
Affinity DataKi:  132nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266408(N-(2-{5-Methoxy-2-[(2-methyl-2,3-dihydro-1H-indol-...)
Affinity DataKi:  148nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50241105((E)-N-[3-(3-methoxyphenyl)-3-phenyl-2-propenyl]ace...)
Affinity DataKi:  230nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266453(N-(2-{5-Methoxy-2-[(6-nitro-2,3-dihydro-1H-indol-1...)
Affinity DataKi:  309nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266406(N-[2-(9-Methoxy-13a,14-dihydro-6H,13H-pyrazino[1,2...)
Affinity DataKi:  320nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266407(N-[2-(2,9-Dimethoxy-13a,14-dihydro-6H,13H-pyrazino...)
Affinity DataKi:  410nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266354(N-(2-((1R,3R)-7-methoxy-3-phenyl-1,2,3,4-tetrahydr...)
Affinity DataKi:  797nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50240442(N-[1-(4-Chloro-benzyl)-4-methoxy-1H-indol-2-ylmeth...)
Affinity DataKi:  1.29E+3nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266433(N-(2-{5-Methoxy-2-[(2,3-dihydro-1H-indol-1yl)methy...)
Affinity DataKi:  1.40E+3nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of WüRzburg

Curated by ChEMBL
LigandPNGBDBM50266407(N-[2-(2,9-Dimethoxy-13a,14-dihydro-6H,13H-pyrazino...)
Affinity DataKi:  1.80E+3nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed