Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50039400
TargetPleiotropic ABC efflux transporter of multiple drugs(Baker's yeast)
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM50339130(4-(2-chloro-10H-phenothiazin-10-yl)butan-1-amine |...)
Affinity DataIC50: 700nMAssay Description:Inhibition of Pdr5p-mediated rhodamine 6G transport in Saccharomyces cerevisiae MKPDR5h plasma membrane by spectrofluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetPleiotropic ABC efflux transporter of multiple drugs(Baker's yeast)
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM50339131(4-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)buta...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Pdr5p-mediated rhodamine 6G transport in Saccharomyces cerevisiae MKPDR5h plasma membrane by spectrofluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetPleiotropic ABC efflux transporter of multiple drugs(Baker's yeast)
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM50002338(10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsul...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Pdr5p-mediated rhodamine 6G transport in Saccharomyces cerevisiae MKPDR5h plasma membrane by spectrofluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetPleiotropic ABC efflux transporter of multiple drugs(Baker's yeast)
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM50130273(4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Pdr5p-mediated rhodamine 6G transport in Saccharomyces cerevisiae MKPDR5h plasma membrane by spectrofluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetPleiotropic ABC efflux transporter of multiple drugs(Baker's yeast)
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM79181(cid_2913535 | TRIFLUOPERAZINE | SMR000059133 | MLS...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Pdr5p-mediated rhodamine 6G transport in Saccharomyces cerevisiae MKPDR5h plasma membrane by spectrofluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetPleiotropic ABC efflux transporter of multiple drugs(Baker's yeast)
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM78433(2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Pdr5p-mediated rhodamine 6G transport in Saccharomyces cerevisiae MKPDR5h plasma membrane by spectrofluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetPleiotropic ABC efflux transporter of multiple drugs(Baker's yeast)
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM78434(2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phen...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Pdr5p-mediated rhodamine 6G transport in Saccharomyces cerevisiae MKPDR5h plasma membrane by spectrofluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetPleiotropic ABC efflux transporter of multiple drugs(Baker's yeast)
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM78436(2-ethylsulfanyl-10-[3-(4-methylpiperazin-1-yl)prop...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of Pdr5p-mediated rhodamine 6G transport in Saccharomyces cerevisiae MKPDR5h plasma membrane by spectrofluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetPleiotropic ABC efflux transporter of multiple drugs(Baker's yeast)
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM50339133(4-(10H-phenothiazin-10-yl)butan-1-amine | CHEMBL16...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of Pdr5p-mediated rhodamine 6G transport in Saccharomyces cerevisiae MKPDR5h plasma membrane by spectrofluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetPleiotropic ABC efflux transporter of multiple drugs(Baker's yeast)
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM50339134(3-(2-Chloro-phenothiazin-10-yl)-propylamine | 3-(2...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of Pdr5p-mediated rhodamine 6G transport in Saccharomyces cerevisiae MKPDR5h plasma membrane by spectrofluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetPleiotropic ABC efflux transporter of multiple drugs(Baker's yeast)
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM50001888([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of Pdr5p-mediated rhodamine 6G transport in Saccharomyces cerevisiae MKPDR5h plasma membrane by spectrofluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetPleiotropic ABC efflux transporter of multiple drugs(Baker's yeast)
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM67544(TRIFLUPROMAZINE | SR-01000000224-4 | N,N-dimethyl-...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of Pdr5p-mediated rhodamine 6G transport in Saccharomyces cerevisiae MKPDR5h plasma membrane by spectrofluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetPleiotropic ABC efflux transporter of multiple drugs(Baker's yeast)
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM50240514((3Z)-3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dim...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of Pdr5p-mediated rhodamine 6G transport in Saccharomyces cerevisiae MKPDR5h plasma membrane by spectrofluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetPleiotropic ABC efflux transporter of multiple drugs(Baker's yeast)
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM50339135(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)prop...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of Pdr5p-mediated rhodamine 6G transport in Saccharomyces cerevisiae MKPDR5h plasma membrane by spectrofluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetPleiotropic ABC efflux transporter of multiple drugs(Baker's yeast)
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM50339136(3-(10H-phenothiazin-10-yl)propan-1-amine | 3-Pheno...)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of Pdr5p-mediated rhodamine 6G transport in Saccharomyces cerevisiae MKPDR5h plasma membrane by spectrofluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetPleiotropic ABC efflux transporter of multiple drugs(Baker's yeast)
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM50339137(CHEMBL1323355 | Levomepromazine | Dextromepromazin...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of Pdr5p-mediated rhodamine 6G transport in Saccharomyces cerevisiae MKPDR5h plasma membrane by spectrofluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetPleiotropic ABC efflux transporter of multiple drugs(Baker's yeast)
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM50418049(CL 36467 | CL 39743 | LEVOMEPROMAZINE | med.21724,...)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of Pdr5p-mediated rhodamine 6G transport in Saccharomyces cerevisiae MKPDR5h plasma membrane by spectrofluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetPleiotropic ABC efflux transporter of multiple drugs(Baker's yeast)
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM50339139(Diethazine | CHEMBL1620412)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of Pdr5p-mediated rhodamine 6G transport in Saccharomyces cerevisiae MKPDR5h plasma membrane by spectrofluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetPleiotropic ABC efflux transporter of multiple drugs(Baker's yeast)
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM67545(cid_5887 | PROMAZINE | SR-01000000228-4 | N,N-dime...)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of Pdr5p-mediated rhodamine 6G transport in Saccharomyces cerevisiae MKPDR5h plasma membrane by spectrofluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetPleiotropic ABC efflux transporter of multiple drugs(Baker's yeast)
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM50017696(N,N,alpha-trimethyl-10H-phenothiazine-10-ethanamin...)
Affinity DataIC50: 1.77E+4nMAssay Description:Inhibition of Pdr5p-mediated rhodamine 6G transport in Saccharomyces cerevisiae MKPDR5h plasma membrane by spectrofluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetPleiotropic ABC efflux transporter of multiple drugs(Baker's yeast)
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM50010859(CHEMBL11 | Imipramin | IMIPRAMINE HYDROCHLORIDE | ...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of Pdr5p-mediated rhodamine 6G transport in Saccharomyces cerevisiae MKPDR5h plasma membrane by spectrofluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetPleiotropic ABC efflux transporter of multiple drugs(Baker's yeast)
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM50012855(phenothiazine | cid_7108 | dibenzo-1,4-thiazine | ...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of Pdr5p-mediated rhodamine 6G transport in Saccharomyces cerevisiae MKPDR5h plasma membrane by spectrofluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetPleiotropic ABC efflux transporter of multiple drugs(Baker's yeast)
Wroclaw Medical University

Curated by ChEMBL
LigandPNGBDBM50292474(7-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylam...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of Pdr5p-mediated rhodamine 6G transport in Saccharomyces cerevisiae MKPDR5h plasma membrane by spectrofluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed