Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50030242
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50208999(BX-741 | BX-471 | (R)-1-(5-chloro-2-(2-(4-(4-fluor...)
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at human CCR1 in THP1 cells assessed as inhibition of MIP-1-alpha-induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50208999(BX-741 | BX-471 | (R)-1-(5-chloro-2-(2-(4-(4-fluor...)
Affinity DataIC50: 5.5nMAssay Description:Displacement of [125I]MIP-1-alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293055((R)-N2-(4-Chlorobenzyl)-N1-[2,6-dimethyl-4-(triflu...)
Affinity DataIC50: 6nMAssay Description:Antagonist activity at human CCR1 in THP1 cells assessed as inhibition of MIP-1-alpha-induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293055((R)-N2-(4-Chlorobenzyl)-N1-[2,6-dimethyl-4-(triflu...)
Affinity DataIC50: 11nMAssay Description:Displacement of [125I]MIP-1-alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293054((R)-N2-(4-Chlorobenzyl)-N2-methyl-N1-[2-methyl-4-(...)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at human CCR1 in THP1 cells assessed as inhibition of MIP-1-alpha-induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293053((R)-N2-(4-Chlorobenzyl)-N1-[2-fluoro-4-(trifluorom...)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at human CCR1 in THP1 cells assessed as inhibition of MIP-1-alpha-induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293051((R)-N2-(4-Chlorobenzyl)-N2-methyl-N1-[4-(trifluoro...)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at human CCR1 in THP1 cells assessed as inhibition of MIP-1-alpha-induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293053((R)-N2-(4-Chlorobenzyl)-N1-[2-fluoro-4-(trifluorom...)
Affinity DataIC50: 23nMAssay Description:Displacement of [125I]MIP-1-alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293052((R)-N2-(4-Chlorobenzyl)-N1-[2-chloro-4-(trifluorom...)
Affinity DataIC50: 35nMAssay Description:Antagonist activity at human CCR1 in THP1 cells assessed as inhibition of MIP-1-alpha-induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293054((R)-N2-(4-Chlorobenzyl)-N2-methyl-N1-[2-methyl-4-(...)
Affinity DataIC50: 50nMAssay Description:Displacement of [125I]MIP-1-alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293052((R)-N2-(4-Chlorobenzyl)-N1-[2-chloro-4-(trifluorom...)
Affinity DataIC50: 120nMAssay Description:Displacement of [125I]MIP-1-alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293051((R)-N2-(4-Chlorobenzyl)-N2-methyl-N1-[4-(trifluoro...)
Affinity DataIC50: 140nMAssay Description:Displacement of [125I]MIP-1-alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293035((R)-N2-(4-Chlorobenzyl)-N1-(4-chlorophenyl)-N2-met...)
Affinity DataIC50: 270nMAssay Description:Displacement of [125I]MIP-1-alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293034((R)-N2-(4-Chlorobenzyl)-N1-(4-chlorophenyl)-N2-eth...)
Affinity DataIC50: 270nMAssay Description:Displacement of [125I]MIP-1-alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293049((R)-N2-(4-Chlorobenzyl)-N1-(4-methoxyphenyl)-N2-me...)
Affinity DataIC50: 290nMAssay Description:Displacement of [125I]MIP-1-alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293049((R)-N2-(4-Chlorobenzyl)-N1-(4-methoxyphenyl)-N2-me...)
Affinity DataIC50: 440nMAssay Description:Antagonist activity at human CCR1 in THP1 cells assessed as inhibition of MIP-1-alpha-induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293059((R)-N2-(4-Chlorobenzyl)-N1-(4-chlorophenyl)-N2-(2-...)
Affinity DataIC50: 540nMAssay Description:Displacement of [125I]MIP-1-alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293046((R)-N2-(4-Chlorobenzyl)-N2-methyl-N1-p-tolylpyrrol...)
Affinity DataIC50: 680nMAssay Description:Displacement of [125I]MIP-1-alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293047((R)-N2-(4-Chlorobenzyl)-N1-(4-fluorophenyl)-N2-met...)
Affinity DataIC50: 700nMAssay Description:Displacement of [125I]MIP-1-alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293048((R)-N2-(4-Chlorobenzyl)-N1-(4-cyanophenyl)-N2-meth...)
Affinity DataIC50: 720nMAssay Description:Displacement of [125I]MIP-1-alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293041((R)-N2-(4-Fluorobenzyl)-N1-(4-chlorophenyl)-N2-met...)
Affinity DataIC50: 1.30E+3nMAssay Description:Displacement of [125I]MIP-1-alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293050((R)-N2-(4-Chlorobenzyl)-N2-methyl-N1-(3-(trifluoro...)
Affinity DataIC50: 2.95E+3nMAssay Description:Displacement of [125I]MIP-1-alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293033((R)-N2-(4-Chlorobenzyl)-N1-(4-chlorophenyl)-N2-pro...)
Affinity DataIC50: 3.60E+3nMAssay Description:Displacement of [125I]MIP-1-alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293044((R)-N2-(4-Chloro-3-methylbenzyl)-N1-(4-chloropheny...)
Affinity DataIC50: 4.00E+3nMAssay Description:Displacement of [125I]MIP-1-alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293045((2R)-N1-(4-Chlorophenyl)-N2-[1-(4-chlorophenyl)eth...)
Affinity DataIC50: 4.70E+3nMAssay Description:Displacement of [125I]MIP-1-alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293042((R)-N2-(4-Methylbenzyl)-N1-(4-chlorophenyl)-N2-met...)
Affinity DataIC50: 5.70E+3nMAssay Description:Displacement of [125I]MIP-1-alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293038((R)-N2-(4-Cyanobenzyl)-N1-(4-chlorophenyl)-N2-meth...)
Affinity DataIC50: 1.30E+4nMAssay Description:Displacement of [125I]MIP-1-alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293056(N2-(4-Chlorobenzyl)-N2-methyl-N1-[4-(trifluorometh...)
Affinity DataIC50: 2.80E+4nMAssay Description:Displacement of [125I]MIP-1-alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293058((S)-N2-(4-Chlorobenzyl)-N2-methyl-N1-[4-(trifluoro...)
Affinity DataIC50: 2.80E+4nMAssay Description:Displacement of [125I]MIP-1-alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293036((R)-N2-(2-Chlorobenzyl)-N1-(4-chlorophenyl)-N2-(2-...)
Affinity DataIC50: 4.30E+4nMAssay Description:Displacement of [125I]MIP-1-alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293032((R)-N2-(4-Chlorobenzyl)-N1-(4-chlorophenyl)pyrroli...)
Affinity DataIC50: 7.50E+4nMAssay Description:Displacement of [125I]MIP-1-alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293039((R)-N2-(4-Methoxybenzyl)-N1-(4-chlorophenyl)-N2-me...)
Affinity DataIC50: 7.70E+4nMAssay Description:Displacement of [125I]MIP-1-alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293040((R)-N2-[4-(Trifluoromethyl)benzyl]-N1-(4-chlorophe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [125I]MIP-1-alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293057((R)-N2-(4-Chlorobenzyl)-N2-methyl-N1-[4-(trifluoro...)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [125I]MIP-1-alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293037((R)-N2-(3-Chlorobenzyl)-N1-(4-chlorophenyl)-N2-(2-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [125I]MIP-1-alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50293043((R)-N2-(4-Chloro-2-methylbenzyl)-N1-(4-chloropheny...)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [125I]MIP-1-alpha from human recombinant CCR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed