Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50028180
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248522(CHEMBL489332 | US8551988, 67 | N-hydroxy-3-(2-phen...)
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248476(US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248570(CHEMBL460963 | US8551988, 17 | 3-(1-(3-(dimethylam...)
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248375(US8551988, 2 | CHEMBL491688 | N-hydroxy-3-(2-phene...)
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248475(US8551988, 66 | CHEMBL491491 | 3-(1-(2-(diethylami...)
Affinity DataIC50: 52nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248314(US8551988, 1 | CHEMBL474746 | N-hydroxy-3-(1-(3-hy...)
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248261(US8551988, 21 | CHEMBL475145 | N-hydroxy-3-(1-(3-h...)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248256(3-(1-(4-(dimethylamino)butyl)-2-phenethyl-1H-benzo...)
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248524(US8551988, 56 | CHEMBL523601 | 3-(1-(3-(1H-imidazo...)
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM103534(CHEMBL474152 | US8551988, 14 | US10201527, Compoun...)
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248431(CHEMBL489125 | US8551988, 36 | N-hydroxy-3-(2-phen...)
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248316(CHEMBL515906 | US8551988, 50 | N-hydroxy-3-(2-phen...)
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248315(CHEMBL442585 | US8551988, 19 | 3-(2-(benzyloxymeth...)
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248573(N-hydroxy-3-(2-phenethyl-1-(3,4,5-trimethoxybenzyl...)
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248525(CHEMBL489331 | US8551988, 63 | 3-(1-(3-(dimethylam...)
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248473(US8551988, 30 | CHEMBL523646 | N-hydroxy-3-(1-(3-(...)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248432(CHEMBL521909 | US8551988, 15 | N-hydroxy-3-(1-(3-m...)
Affinity DataIC50: 210nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248376(3-(1-ethyl-2-phenethyl-1H-benzo[d]imidazol-5-yl)-N...)
Affinity DataIC50: 220nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50247927(CHEMBL489706 | US8551988, 16 | N-hydroxy-3-(2-phen...)
Affinity DataIC50: 250nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248474(US8551988, 31 | CHEMBL491490 | N-hydroxy-3-(1-(3-m...)
Affinity DataIC50: 250nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM38236(CHEMBL522269 | US8551988, 38 | US10201527, Compoun...)
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248429(N-hydroxy-3-(1-(2-morpholinoethyl)-2-phenethyl-1H-...)
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248523(US8551988, 82 | CHEMBL489330 | N-hydroxy-3-(2-phen...)
Affinity DataIC50: 310nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM38237(CHEMBL491687 | US8551988, 33 | US10201527, Compoun...)
Affinity DataIC50: 410nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248312(US8551988, 23 | CHEMBL474151 | N-hydroxy-3-(1-(3-h...)
Affinity DataIC50: 530nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248430(CHEMBL489124 | US8551988, 26 | 3-(1,2-diphenethyl-...)
Affinity DataIC50: 880nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248257((E)-N-hydroxy-3-(1-(3-hydroxypropyl)-1H-benzo[d]im...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50247926(3-(1-benzyl-2-phenethyl-1H-benzo[d]imidazol-6-yl)-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248574(N-hydroxy-2-(1-methyl-2-phenethyl-1H-benzo[d]imida...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248260(CHEMBL474547 | US8551988, 46 | N-hydroxy-3-(1-(3-h...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248259(US8551988, 20 | CHEMBL474546 | N-hydroxy-3-(1-(3-h...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248377(US8551988, 32 | CHEMBL490722 | 3-(5-(3-(hydroxyami...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248258(CHEMBL474350 | US8551988, 24 | 3-(2-cyclohexyl-1-(...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248572(CHEMBL464718 | US8551988, 40 | N-hydroxy-1-(3-hydr...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248571(CHEMBL461173 | US8551988, 29 | N-hydroxy-3-(1-(3-h...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50247928(N-(2-aminophenyl)-3-(2-phenethyl-1-(pyridin-2-ylme...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 4(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248476(US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...)
Affinity DataKi:  9.60nMAssay Description:Inhibition of recombinant HDAC4 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 11(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248476(US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...)
Affinity DataKi:  13nMAssay Description:Inhibition of recombinant HDAC11 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 3(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248476(US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...)
Affinity DataKi:  13nMAssay Description:Inhibition of recombinant HDAC3 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 5(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248476(US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...)
Affinity DataKi:  17nMAssay Description:Inhibition of recombinant HDAC5 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248476(US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...)
Affinity DataKi:  19nMAssay Description:Inhibition of recombinant HDAC10 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 9(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248476(US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...)
Affinity DataKi:  19nMAssay Description:Inhibition of recombinant HDAC9 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248476(US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...)
Affinity DataKi:  21nMAssay Description:Inhibition of recombinant HDAC6 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 2(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248476(US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...)
Affinity DataKi:  36nMAssay Description:Inhibition of recombinant HDAC2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50248476(US8551988, 72 | CHEMBL491316 | SB-639 | N-hydroxy-...)
Affinity DataKi:  82nMAssay Description:Inhibition of recombinant HDAC8 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed