Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50004172
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50479681(CHEMBL478258)
Affinity DataKon:  0.0000210M-1s-1Assay Description:Binding affinity to HIV1 reverse transcriptase treated for 3 mins by surface plasmon resonanceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM2483(Sustiva | DMP-266 | (4S)-6-chloro-4-(2-cyclopropyl...)
Affinity DataKi:  4nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase-DNA-dNTP ternary complexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50479681(CHEMBL478258)
Affinity DataKi:  8nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase-DNA binary complexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50479681(CHEMBL478258)
Affinity DataKi:  9nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase-DNA-dNTP ternary complexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50479681(CHEMBL478258)
Affinity DataKi:  10nMAssay Description:Inhibition of wild type HIV1 free reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50479680(CHEMBL459082)
Affinity DataKi:  30nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase-DNA binary complexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM2483(Sustiva | DMP-266 | (4S)-6-chloro-4-(2-cyclopropyl...)
Affinity DataKi:  30nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase-DNA binary complexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM2483(Sustiva | DMP-266 | (4S)-6-chloro-4-(2-cyclopropyl...)
Affinity DataKi:  30nMAssay Description:Inhibition of wild type HIV1 free reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50479681(CHEMBL478258)
Affinity DataKi:  30nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase K103N mutant-DNA-dNTP ternary complex expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50479681(CHEMBL478258)
Affinity DataKi:  40nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase K103N mutant-DNA binary complex expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50479680(CHEMBL459082)
Affinity DataKi:  40nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase-DNA-dNTP ternary complexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50479680(CHEMBL459082)
Affinity DataKi:  40nMAssay Description:Inhibition of wild type HIV1 free reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50479681(CHEMBL478258)
Affinity DataKi:  65nMAssay Description:Inhibition of HIV1 recombinant free reverse transcriptase K103N mutant expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM2483(Sustiva | DMP-266 | (4S)-6-chloro-4-(2-cyclopropyl...)
Affinity DataKi:  200nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase K103N mutant-DNA-dNTP ternary complex expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50479680(CHEMBL459082)
Affinity DataKi:  300nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase K103N mutant-DNA-dNTP ternary complex expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM1434(BI-RG-587 | 2-cyclopropyl-7-methyl-2,4,9,15-tetraa...)
Affinity DataKi:  400nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase-DNA-dNTP ternary complexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50479680(CHEMBL459082)
Affinity DataKi:  400nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase K103N mutant-DNA binary complex expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM1434(BI-RG-587 | 2-cyclopropyl-7-methyl-2,4,9,15-tetraa...)
Affinity DataKi:  400nMAssay Description:Inhibition of wild type HIV1 free reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM1434(BI-RG-587 | 2-cyclopropyl-7-methyl-2,4,9,15-tetraa...)
Affinity DataKi:  500nMAssay Description:Inhibition of wild type HIV1 reverse transcriptase-DNA binary complexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50479680(CHEMBL459082)
Affinity DataKi:  600nMAssay Description:Inhibition of HIV1 recombinant free reverse transcriptase K103N mutant expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM2483(Sustiva | DMP-266 | (4S)-6-chloro-4-(2-cyclopropyl...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of HIV1 recombinant free reverse transcriptase K103N mutant expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM2483(Sustiva | DMP-266 | (4S)-6-chloro-4-(2-cyclopropyl...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase K103N mutant-DNA binary complex expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM1434(BI-RG-587 | 2-cyclopropyl-7-methyl-2,4,9,15-tetraa...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase K103N mutant-DNA binary complex expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM1434(BI-RG-587 | 2-cyclopropyl-7-methyl-2,4,9,15-tetraa...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of HIV1 recombinant free reverse transcriptase K103N mutant expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
University of Siena

Curated by ChEMBL
LigandPNGBDBM1434(BI-RG-587 | 2-cyclopropyl-7-methyl-2,4,9,15-tetraa...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase K103N mutant-DNA-dNTP ternary complex expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed