Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50028100
TargetTranscription factor p65(Human)
Columbia University

Curated by ChEMBL
LigandPNGBDBM50135482(1-(5-Methoxy-2-thiophen-2-yl-quinazolin-4-ylamino)...)
Affinity DataEC50:  380nMAssay Description:Potentiation of TNF-alpha-induced NF-kappaB p65 nuclear translocation in HUVEC cells by immunostainingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTranscription factor p65(Human)
Columbia University

Curated by ChEMBL
LigandPNGBDBM50277067(1-(8-chloro-5-methoxy-2-(thiophen-2-yl)quinazolin-...)
Affinity DataEC50:  310nMAssay Description:Potentiation of TNF-alpha-induced NF-kappaB p65 nuclear translocation in HUVEC cells by immunostainingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTranscription factor p65(Human)
Columbia University

Curated by ChEMBL
LigandPNGBDBM50135483(1-(6-methoxy-2-(thiophen-2-yl)quinazolin-4-ylamino...)
Affinity DataEC50:  4.20E+4nMAssay Description:Potentiation of TNF-alpha-induced NF-kappaB p65 nuclear translocation in HUVEC cells by immunostainingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTranscription factor p65(Human)
Columbia University

Curated by ChEMBL
LigandPNGBDBM50277067(1-(8-chloro-5-methoxy-2-(thiophen-2-yl)quinazolin-...)
Affinity DataEC50:  2.40E+3nMAssay Description:Induction of NF-kappaB p65 nuclear translocation in HUVEC cells by immunostainingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTranscription factor p65(Human)
Columbia University

Curated by ChEMBL
LigandPNGBDBM50135482(1-(5-Methoxy-2-thiophen-2-yl-quinazolin-4-ylamino)...)
Affinity DataEC50:  1.60E+3nMAssay Description:Induction of NF-kappaB p65 nuclear translocation in HUVEC cells by immunostainingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTranscription factor p65(Human)
Columbia University

Curated by ChEMBL
LigandPNGBDBM50135483(1-(6-methoxy-2-(thiophen-2-yl)quinazolin-4-ylamino...)
Affinity DataEC50:  9.80E+3nMAssay Description:Induction of NF-kappaB p65 nuclear translocation in HUVEC cells by immunostainingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed