Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50028085
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255219((+/-)-benzyl3-(4-(methylthio)benzamido)-4-( 2-(3-(...)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at CCR2 in human monocytes assessed as inhibition of MCP1-induced calcium influx by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255171((+/-)-2-amino-N-(2-(5-(isopropylamino)-2-(4-(methy...)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at CCR2 in human monocytes assessed as inhibition of MCP1-induced calcium influx by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255219((+/-)-benzyl3-(4-(methylthio)benzamido)-4-( 2-(3-(...)
Affinity DataIC50: 2.40nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255738((+/-)-N-(2-(4-(dimethylamino)-2-(4-(methylthio)ben...)
Affinity DataIC50: 2.40nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255221((+/-)-N-(2-(2-((1H-indol-5-yl)methylamino)-4-(dime...)
Affinity DataIC50: 3.10nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255171((+/-)-2-amino-N-(2-(5-(isopropylamino)-2-(4-(methy...)
Affinity DataIC50: 3.80nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255737((+/-)-2-amino-N-(2-(4-amino-2-(4-(methylthio)benza...)
Affinity DataIC50: 4.80nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255219((+/-)-benzyl3-(4-(methylthio)benzamido)-4-( 2-(3-(...)
Affinity DataIC50: 5.10nMAssay Description:Antagonist activity at CCR2 in human PBMCs assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255739((+/-)-N-(2-(4-(dimethylamino)-2-(4-methylbenzylami...)
Affinity DataIC50: 5.5nMAssay Description:Antagonist activity at CCR2 in human monocytes assessed as inhibition of MCP1-induced calcium influx by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255737((+/-)-2-amino-N-(2-(4-amino-2-(4-(methylthio)benza...)
Affinity DataIC50: 6nMAssay Description:Antagonist activity at CCR2 in human monocytes assessed as inhibition of MCP1-induced calcium influx by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255738((+/-)-N-(2-(4-(dimethylamino)-2-(4-(methylthio)ben...)
Affinity DataIC50: 6nMAssay Description:Antagonist activity at CCR2 in human monocytes assessed as inhibition of MCP1-induced calcium influx by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255219((+/-)-benzyl3-(4-(methylthio)benzamido)-4-( 2-(3-(...)
Affinity DataIC50: 7nMAssay Description:Inhibition of CCR3 at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255799((+/-)-N-(2-(2-(4-chlorobenzylamino)-4-(dimethylami...)
Affinity DataIC50: 7nMAssay Description:Antagonist activity at CCR2 in human monocytes assessed as inhibition of MCP1-induced calcium influx by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255175((+/-)-N-(2-(2-(4-acetamidobenzylamino)-4-(dimethyl...)
Affinity DataIC50: 7.70nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255798((+/-)-N-(2-(4-(dimethylamino)-2-(4-methoxybenzylam...)
Affinity DataIC50: 8nMAssay Description:Antagonist activity at CCR2 in human monocytes assessed as inhibition of MCP1-induced calcium influx by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255221((+/-)-N-(2-(2-((1H-indol-5-yl)methylamino)-4-(dime...)
Affinity DataIC50: 8nMAssay Description:Antagonist activity at CCR2 in human monocytes assessed as inhibition of MCP1-induced calcium influx by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255739((+/-)-N-(2-(4-(dimethylamino)-2-(4-methylbenzylami...)
Affinity DataIC50: 9.90nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255798((+/-)-N-(2-(4-(dimethylamino)-2-(4-methoxybenzylam...)
Affinity DataIC50: 12.5nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255739((+/-)-N-(2-(4-(dimethylamino)-2-(4-methylbenzylami...)
Affinity DataIC50: 12.6nMAssay Description:Antagonist activity at CCR2 in human PBMCs assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255737((+/-)-2-amino-N-(2-(4-amino-2-(4-(methylthio)benza...)
Affinity DataIC50: 13.5nMAssay Description:Antagonist activity at CCR2 in human PBMCs assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255799((+/-)-N-(2-(2-(4-chlorobenzylamino)-4-(dimethylami...)
Affinity DataIC50: 16nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255797((+/-)-N-(2-(4-(dimethylamino)-2-(4-isopropylbenzyl...)
Affinity DataIC50: 16.5nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255175((+/-)-N-(2-(2-(4-acetamidobenzylamino)-4-(dimethyl...)
Affinity DataIC50: 17.4nMAssay Description:Antagonist activity at CCR2 in human PBMCs assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255797((+/-)-N-(2-(4-(dimethylamino)-2-(4-isopropylbenzyl...)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at CCR2 in human monocytes assessed as inhibition of MCP1-induced calcium influx by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255735((+/-)-2-amino-N-(2-(4-(4-(methylthio)benzamido)pip...)
Affinity DataIC50: 19.7nMAssay Description:Inhibition of CCR3 at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255738((+/-)-N-(2-(4-(dimethylamino)-2-(4-(methylthio)ben...)
Affinity DataIC50: 22.5nMAssay Description:Antagonist activity at CCR2 in human PBMCs assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255221((+/-)-N-(2-(2-((1H-indol-5-yl)methylamino)-4-(dime...)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at CCR2 in human PBMCs assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255174((+/-)-N-(2-(4-(dimethylamino)-2-(3-(trifluoromethy...)
Affinity DataIC50: 27nMAssay Description:Antagonist activity at CCR2 in human monocytes assessed as inhibition of MCP1-induced calcium influx by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255171((+/-)-2-amino-N-(2-(5-(isopropylamino)-2-(4-(methy...)
Affinity DataIC50: 27.2nMAssay Description:Inhibition of CCR3 at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255735((+/-)-2-amino-N-(2-(4-(4-(methylthio)benzamido)pip...)
Affinity DataIC50: 28nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255174((+/-)-N-(2-(4-(dimethylamino)-2-(3-(trifluoromethy...)
Affinity DataIC50: 32.5nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255798((+/-)-N-(2-(4-(dimethylamino)-2-(4-methoxybenzylam...)
Affinity DataIC50: 41.4nMAssay Description:Antagonist activity at CCR2 in human PBMCs assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255800((+/-)-N-(2-(2-(3,4-dichlorobenzylamino)-4-(dimethy...)
Affinity DataIC50: 61.5nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255735((+/-)-2-amino-N-(2-(4-(4-(methylthio)benzamido)pip...)
Affinity DataIC50: 75nMAssay Description:Antagonist activity at CCR2 in human monocytes assessed as inhibition of MCP1-induced calcium influx by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255735((+/-)-2-amino-N-(2-(4-(4-(methylthio)benzamido)pip...)
Affinity DataIC50: 109nMAssay Description:Antagonist activity at CCR2 in human PBMCs assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255170((+/-)-2-amino-N-(2-(2-(4-(methylthio)benzamido)-5-...)
Affinity DataIC50: 112nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255218((+/-)-N-(2-(5-(isopropylamino)-2-(4-(methylthio)be...)
Affinity DataIC50: 136nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255734((+/-)-2-amino-N-(2-(2-(4-(methylthio)benzamido)cyc...)
Affinity DataIC50: 155nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255217((+/-)-2-amino-N-(2-(5-amino 2-(4-(methylthio)benza...)
Affinity DataIC50: 168nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255220((+/-)-N-(2-(4-amino-2-(4-(methylthio)benzamido)cyc...)
Affinity DataIC50: 228nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255736((+/-)-[2-({[5-Benzyloxycarbonylamino-2-(4-methylsu...)
Affinity DataIC50: 600nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255172((+/-)-benzyl4-(4-(methylthio)benzamido)-3-(2-(3-(t...)
Affinity DataIC50: 1.61E+3nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed