Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50028077
TargetCannabinoid receptor 1(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50255203((4-amino-1-(4-chlorobenzyl)-2-methyl-5-phenyl-1H-p...)
Affinity DataEC50:  4.90E+3nMAssay Description:Antagonist activity at CB1 receptor in rat cerebellar membrane assessed as inhibition of WIN-55212-2-induced [35S]GTPgammaS binding by liquid scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM21278(SR141716 | 5-(4-chlorophenyl)-1-(2,4-dichloropheny...)
Affinity DataIC50: 5.20nMAssay Description:Displacement of [3H]WIN-55212-2 from CB1 receptor in rat cerebellar membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50255199(1-(4-Chloro-benzyl)-2-methyl-5-phenyl-1H-pyrrole-3...)
Affinity DataIC50: 11nMAssay Description:Displacement of [3H]WIN-55212-2 from human CB2 receptor expressed in CHO-K1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50255203((4-amino-1-(4-chlorobenzyl)-2-methyl-5-phenyl-1H-p...)
Affinity DataIC50: 41nMAssay Description:Displacement of [3H]WIN-55212-2 from human CB2 receptor expressed in CHO-K1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50255199(1-(4-Chloro-benzyl)-2-methyl-5-phenyl-1H-pyrrole-3...)
Affinity DataIC50: 70nMAssay Description:Displacement of [3H]WIN-55212-2 from CB1 receptor in rat cerebellar membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50255200(4-Bromo-1-(4-chloro-benzyl)-2-methyl-5-phenyl-1H-p...)
Affinity DataIC50: 123nMAssay Description:Displacement of [3H]WIN-55212-2 from human CB2 receptor expressed in CHO-K1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50255203((4-amino-1-(4-chlorobenzyl)-2-methyl-5-phenyl-1H-p...)
Affinity DataIC50: 313nMAssay Description:Displacement of [3H]WIN-55212-2 from CB1 receptor in rat cerebellar membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50255157(1-(4-chlorobenzyl)-2-methyl-5-phenyl-1H-pyrrole-3-...)
Affinity DataIC50: 420nMAssay Description:Displacement of [3H]WIN-55212-2 from human CB2 receptor expressed in CHO-K1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50255202((1-(4-chlorobenzyl)-2-methyl-5-phenyl-1H-pyrrol-3-...)
Affinity DataIC50: 498nMAssay Description:Displacement of [3H]WIN-55212-2 from human CB2 receptor expressed in CHO-K1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50255200(4-Bromo-1-(4-chloro-benzyl)-2-methyl-5-phenyl-1H-p...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]WIN-55212-2 from CB1 receptor in rat cerebellar membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50255157(1-(4-chlorobenzyl)-2-methyl-5-phenyl-1H-pyrrole-3-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]WIN-55212-2 from CB1 receptor in rat cerebellar membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50255201((4-amino-2-methyl-5-phenyl-1H-pyrrol-3-yl)(phenyl)...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]WIN-55212-2 from human CB2 receptor expressed in CHO-K1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM21278(SR141716 | 5-(4-chlorophenyl)-1-(2,4-dichloropheny...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]WIN-55212-2 from human CB2 receptor expressed in CHO-K1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50255156(1-(4-chlorobenzyl)-2-methyl-5-phenyl-1H-pyrrole-3-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]WIN-55212-2 from CB1 receptor in rat cerebellar membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50255201((4-amino-2-methyl-5-phenyl-1H-pyrrol-3-yl)(phenyl)...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]WIN-55212-2 from CB1 receptor in rat cerebellar membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50255202((1-(4-chlorobenzyl)-2-methyl-5-phenyl-1H-pyrrol-3-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]WIN-55212-2 from CB1 receptor in rat cerebellar membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50255156(1-(4-chlorobenzyl)-2-methyl-5-phenyl-1H-pyrrole-3-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]WIN-55212-2 from human CB2 receptor expressed in CHO-K1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM21278(SR141716 | 5-(4-chlorophenyl)-1-(2,4-dichloropheny...)
Affinity DataKi:  1.98nMAssay Description:Displacement of [3H]WIN-55212-2 from CB1 receptor in rat cerebellar membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed