Compile Data Set for Download or QSAR
Report error Found 57 Enz. Inhib. hit(s) with all data for entry = 50028054
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255778(3-(1-(2,3-dichlorobenzyl)-3a-methyl-2-oxo-2,3,3a,4...)
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at human EP3 receptor expressed in CHO-K1 cells assessed as reversal of inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255343(3-(1-(3,4-difluorobenzyl)-3a-methyl-2-oxo-2,3,3a,4...)
Affinity DataIC50: 1.80nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255780(3-(1-(3-chlorobenzyl)-3a-methyl-2-oxo-2,3,3a,4,5,6...)
Affinity DataIC50: 2.20nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255779(3-(1-(2,4-dichlorobenzyl)-3a-methyl-2-oxo-2,3,3a,4...)
Affinity DataIC50: 2.30nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255125(N-(3,4-difluorophenylsulfonyl)-3-(1-(4-fluorobenzy...)
Affinity DataIC50: 2.5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255286(N-(3,5-dichlorophenylsulfonyl)-3-(1-(3,4-difluorob...)
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at human EP3 receptor expressed in CHO-K1 cells assessed as reversal of inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255944(3-(1-(2,3-dichlorobenzyl)-3a-methyl-2-oxo-2,3,3a,4...)
Affinity DataIC50: 3.40nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255123(3-(1-(2,4-dichlorobenzyl)-3a-methyl-2-oxo-2,3,3a,4...)
Affinity DataIC50: 3.40nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255944(3-(1-(2,3-dichlorobenzyl)-3a-methyl-2-oxo-2,3,3a,4...)
Affinity DataIC50: 3.5nMAssay Description:Antagonist activity at human EP3 receptor expressed in CHO-K1 cells assessed as reversal of inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255839(N-(4,5-dichlorothiophen-2-ylsulfonyl)-3-(1-(3,4-di...)
Affinity DataIC50: 3.5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255283(3-(1-(3,4-difluorobenzyl)-3a-methyl-2-oxo-2,3,3a,4...)
Affinity DataIC50: 3.5nMAssay Description:Antagonist activity at human EP3 receptor expressed in CHO-K1 cells assessed as reversal of inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255169(3-(1-(2,4-dichlorobenzyl)-3a-methyl-2-oxo-2,3,3a,4...)
Affinity DataIC50: 3.70nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255889(3-(1-(2,3-dichlorobenzyl)-3a-methyl-2-oxo-2,3,3a,4...)
Affinity DataIC50: 3.80nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255840(N-(4,5-dichlorothiophen-2-ylsulfonyl)-3-(1-(4-fluo...)
Affinity DataIC50: 3.80nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255126(3-(1-(2,3-dichlorobenzyl)-3a-methyl-2-oxo-2,3,3a,4...)
Affinity DataIC50: 4.30nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255778(3-(1-(2,3-dichlorobenzyl)-3a-methyl-2-oxo-2,3,3a,4...)
Affinity DataIC50: 4.40nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255126(3-(1-(2,3-dichlorobenzyl)-3a-methyl-2-oxo-2,3,3a,4...)
Affinity DataIC50: 4.5nMAssay Description:Antagonist activity at human EP3 receptor expressed in CHO-K1 cells assessed as reversal of inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255839(N-(4,5-dichlorothiophen-2-ylsulfonyl)-3-(1-(3,4-di...)
Affinity DataIC50: 5.20nMAssay Description:Antagonist activity at human EP3 receptor expressed in CHO-K1 cells assessed as reversal of inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255286(N-(3,5-dichlorophenylsulfonyl)-3-(1-(3,4-difluorob...)
Affinity DataIC50: 5.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255942(N-(3,5-difluorophenylsulfonyl)-3-(1-(3-methoxybenz...)
Affinity DataIC50: 5.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255284(3-(1-(3-methoxybenzyl)-3a-methyl-2-oxo-2,3,3a,4,5,...)
Affinity DataIC50: 5.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255841(N-(4,5-dichlorothiophen-2-ylsulfonyl)-3-(1-(3-meth...)
Affinity DataIC50: 5.80nMAssay Description:Antagonist activity at human EP3 receptor expressed in CHO-K1 cells assessed as reversal of inhibition of forskolin-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255841(N-(4,5-dichlorothiophen-2-ylsulfonyl)-3-(1-(3-meth...)
Affinity DataIC50: 6.40nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255723(N-(4,5-dichlorothiophen-2-ylsulfonyl)-3-(3a-methyl...)
Affinity DataIC50: 6.80nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255283(3-(1-(3,4-difluorobenzyl)-3a-methyl-2-oxo-2,3,3a,4...)
Affinity DataIC50: 7.70nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255888(3-(1-(3,4-difluorobenzyl)-3a-methyl-2-oxo-2,3,3a,4...)
Affinity DataIC50: 9.20nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255124(3-(1-(3,4-difluorobenzyl)-3a-methyl-2-oxo-2,3,3a,4...)
Affinity DataIC50: 9.40nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255781(N-(4,5-dichlorothiophen-2-ylsulfonyl)-3-(1-(3-fluo...)
Affinity DataIC50: 9.5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255285(3-(1-(2,4-dichlorobenzyl)-3a-methyl-2-oxo-2,3,3a,4...)
Affinity DataIC50: 9.80nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255402(methyl 1-(2,4-dichlorobenzyl)-2-oxo-7-(3-oxo-3-(2,...)
Affinity DataIC50: 11.2nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255943(N-(3,4-difluorophenylsulfonyl)-3-(1-(3-methoxybenz...)
Affinity DataIC50: 12.9nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255842(N-(5-chlorothiophen-2-ylsulfonyl)-3-(1-(2,4-dichlo...)
Affinity DataIC50: 13.4nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255887(3-(1-(2,4-dichlorobenzyl)-3a-methyl-2-oxo-2,3,3a,4...)
Affinity DataIC50: 15.2nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255401(methyl 1-(2,4-dichlorobenzyl)-7-(3-(3,4-difluoroph...)
Affinity DataIC50: 20.6nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255345(methyl 7-(3-(4,5-dichlorothiophene-2-sulfonamido)-...)
Affinity DataIC50: 29.9nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255886(3-(1-(2,4-dichlorobenzyl)-3a-methyl-2-oxo-2,3,3a,4...)
Affinity DataIC50: 57.2nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255941(N-(3,5-difluorophenylsulfonyl)-3-(1-(4-fluorobenzy...)
Affinity DataIC50: 84.1nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255344(3-((3aR,7S,7aR)-1-(3,4-difluorobenzyl)-3a-methyl-2...)
Affinity DataIC50: 557nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255943(N-(3,4-difluorophenylsulfonyl)-3-(1-(3-methoxybenz...)
Affinity DataIC50: 1.40E+3nMAssay Description:Binding affinity to human EP1 receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255124(3-(1-(3,4-difluorobenzyl)-3a-methyl-2-oxo-2,3,3a,4...)
Affinity DataIC50: 2.30E+3nMAssay Description:Binding affinity to human EP2 receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin F2-alpha receptor(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255283(3-(1-(3,4-difluorobenzyl)-3a-methyl-2-oxo-2,3,3a,4...)
Affinity DataIC50: 3.80E+3nMAssay Description:Binding affinity to human FP receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin F2-alpha receptor(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255941(N-(3,5-difluorophenylsulfonyl)-3-(1-(4-fluorobenzy...)
Affinity DataIC50: 4.20E+3nMAssay Description:Binding affinity to human FP receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin F2-alpha receptor(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255841(N-(4,5-dichlorothiophen-2-ylsulfonyl)-3-(1-(3-meth...)
Affinity DataIC50: 6.10E+3nMAssay Description:Binding affinity to human FP receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255283(3-(1-(3,4-difluorobenzyl)-3a-methyl-2-oxo-2,3,3a,4...)
Affinity DataIC50: 6.20E+3nMAssay Description:Binding affinity to human EP4 receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin F2-alpha receptor(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255943(N-(3,4-difluorophenylsulfonyl)-3-(1-(3-methoxybenz...)
Affinity DataIC50: 6.40E+3nMAssay Description:Binding affinity to human FP receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255723(N-(4,5-dichlorothiophen-2-ylsulfonyl)-3-(3a-methyl...)
Affinity DataIC50: 6.90E+3nMAssay Description:Binding affinity to human EP1 receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin F2-alpha receptor(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255126(3-(1-(2,3-dichlorobenzyl)-3a-methyl-2-oxo-2,3,3a,4...)
Affinity DataIC50: 7.40E+3nMAssay Description:Binding affinity to human FP receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255943(N-(3,4-difluorophenylsulfonyl)-3-(1-(3-methoxybenz...)
Affinity DataIC50: 7.50E+3nMAssay Description:Binding affinity to human EP4 receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin F2-alpha receptor(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255169(3-(1-(2,4-dichlorobenzyl)-3a-methyl-2-oxo-2,3,3a,4...)
Affinity DataIC50: 7.60E+3nMAssay Description:Binding affinity to human FP receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255124(3-(1-(3,4-difluorobenzyl)-3a-methyl-2-oxo-2,3,3a,4...)
Affinity DataIC50: 7.70E+3nMAssay Description:Binding affinity to human EP4 receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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